Overview: apoptotic signaling pathways in the immune system

Cell Death: The Significance of Apoptosis

1980 • 7,281 citations

The Inflammasome

2002 • 5,445 citations

Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death

2001 • 3,867 citations

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β

2000 • 3,241 citations

Bid, Bax, and Lipids Cooperate to Form Supramolecular Openings in the Outer Mitochondrial Membrane

2002 • 1,443 citations

A Unified Model for Apical Caspase Activation

2003 • 946 citations

Requirement for Caspase-2 in Stress-Induced Apoptosis Before Mitochondrial Permeabilization

2002 • 727 citations

Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins

2002 • 699 citations

Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome

2002 • 564 citations

Human caspase 12 has acquired deleterious mutations

2002 • 348 citations

Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi

2002 • 311 citations

The procaspase-8 isoform, procaspase-8L, recruited to the BAP31 complex at the endoplasmic reticulum

2002 • 123 citations

The Apoptotic Protease-Activating Factor 1-Mediated Pathway of Apoptosis Is Dispensable for Negative Selection of Thymocytes

2002 • 48 citations