Novel Point Mutation in the Cardiac Transcription Factor CSX/NKX2.5 Associated With Congenital Heart Disease.

Congenital Heart Disease Caused by Mutations in the Transcription Factor NKX2-5

1998 • 1,284 citations

Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5.

1995 • 1,130 citations

Mutations in the cardiac transcription factor NKX2.5 affect diverse cardiac developmental pathways

1999 • 667 citations

The cardiac transcription factors Nkx2-5 and GATA-4 are mutual cofactors

1997 • 660 citations

The cardiac homeobox gene Csx/Nkx2.5 lies genetically upstream of multiple genes essential for heart development

1999 • 552 citations

Csx: a murine homeobox-containing gene specifically expressed in the developing heart.

1993 • 533 citations

Fashioning the vertebrate heart: earliest embryonic decisions

1997 • 490 citations

Molecular Pathways Controlling Heart Development

1996 • 485 citations

Recruitment of the Tinman Homolog Nkx-2.5 by Serum Response Factor Activates Cardiac α-Actin Gene Transcription

1996 • 277 citations

Building the heart piece by piece: modularity of cis-elements regulating Nkx2-5 transcription

1999 • 184 citations

Loss of function and inhibitory effects of human CSX/NKX2.5 homeoprotein mutations associated with congenital heart disease

2000 • 164 citations

Parsing the Heart: Genetic Modules for Organ Assembly

1997 • 163 citations

Identification of the In Vivo Casein Kinase II Phosphorylation Site within the Homeodomain of the Cardiac Tisue-Specifying Homeobox Gene Product Csx/Nkx2.5

1999 • 90 citations

Molecular Cloning and Characterization of Human Cardiac Homeobox Gene CSX1

1996 • 73 citations

Vertebrate homologs oftinman andbagpipe: Roles of the homeobox genes in cardiovascular development

1998 • 73 citations

Functional Analyses of Three Csx/Nkx-2.5 Mutations That Cause Human Congenital Heart Disease

2000 • 59 citations

Familial Atrial Septal Defect and Atrioventricular Conduction Disturbance Associated With a Point Mutation in the Cardiac Homeobox Gene <i>CSX/NKX2-5</i> in a Japanese Patient

1999 • 56 citations

Assignment of Cardiac Homeobox Gene CSX to Human Chromosome 5q34

1995 • 41 citations