The Pretreatment Effect of Chemical Skin Penetration Enhancers in Transdermal Drug Delivery Using Iontophoresis

Epidermal Lipids, Barrier Function, and Desquamation

1983 • 1,296 citations

Mass transport Phenomena and Models: Theoretical Concepts

1974 • 516 citations

Presence of Intact Intercellular Lipid Lamellae in the Upper Layers of the Stratum Corneum

1987 • 363 citations

Role of Stratum Corneum Lipid Fluidity in Transdermal Drug Flux

1987 • 326 citations

Evidence that oleic acid exists in a separate phase within stratum corneum lipids.

1991 • 314 citations

Mechanism of oleic acid-induced skin penetration enhancement in vivo in humans

1995 • 306 citations

Mechanism of Percutaneous Absorption. IV. Penetration of Nonelectrolytes (Alcohols) from Aqueous Solutions and from Pure Liquids

1973 • 280 citations

Oleic acid: its effects on stratum corneum in relation to (trans)dermal drug delivery.

1990 • 221 citations

Characterization of the Pore Transport Properties and Tissue Alteration of Excised Human Skin during Iontophoresis

1988 • 164 citations

Structure/effect studies of fatty acid isomers as skin penetration enhancers and skin irritants.

1989 • 158 citations

Pathways of ionic flow through human skin in vivo

1984 • 142 citations

Sites of Iontophoretic Current Flow Into the Skin: Identification and Characterization with the Vibrating Probe Electrode

1991 • 136 citations

Transdermal Iontophoretic Drug Delivery: Mechanistic Analysis and Application to Polypeptide Delivery

1989 • 125 citations

Control of Blood Glucose Levels in Alloxan-diabetic Rabbits by Iontophoresis of Insulin

1986 • 113 citations

Iontophoresis of Polypeptides: Effect of Ethanol Pretreatment of Human Skin

1990 • 79 citations

Oleic acid concentration and effect in human stratum corneum: non-invasive determination by attenuated total reflectance infrared spectroscopy in vivo

1990 • 74 citations

Relevance of Hairless Mouse as an Experimental Model of Percutaneous Penetration in Man

1998 • 73 citations

Enhancement of the in vitro skin permeability of azidothymidine (AZT) via iontophoresis and chemical enhancer.

1990 • 66 citations

Effect of Penetration Enhancers and Iontophoresis on the Ultrastructure and Cholecystokinin-8 Permeability through Porcine Skin

1997 • 65 citations

Interaction between penetration enhancers and iontophoresis: effect on human skin impedance in vivo

1997 • 55 citations

Iontophoresis Itself on Hairless Mouse Skin Induces the Loss of the Epidermal Calcium Gradient Without Skin Barrier Impairment

1998 • 51 citations

The effect of iontophoresis on skin barrier integrity: non-invasive evaluation by impedance spectroscopy and transepidermal water loss.

1996 • 44 citations

Action of Skin Permeation Enhancers Azone, Oleic Acid and Decylmethyl Sulphoxide: Permeation and Dsc Studies

1986 • 33 citations

Visualization of Iontophoretic Transport Paths in Cultured and Animal Skin Models

1996 • 33 citations

The changes of stratum corneum interstices and calcium distribution of follicular epithelium of experimentally induced comedones (EIC) by oleic acid*

1997 • 30 citations

Vehicle effect on topical drug delivery. IV. Effect of N-methylpyrrolidone and polar lipids on percutaneous drug transport

1988 • 27 citations

Effects of Oleic Acid/Propylene Glycol on Rat Abdominal Stratum Corneum: Lipid Extraction and Appearance of Propylene Glycol in the Dermis Measured by Fourier Transform Infrared/Attenuated Total Reflectance(FT-IR/ATR) Spectroscopy.

1993 • 25 citations

Behavior of Propylene Glycol (PG) in Dermis after Treatment of Rat Intact Skin Surface with Fatty Acids, Fatty Amines or Azone Dissolved in PG.

1995 • 19 citations

The Effect of Saline Iontophoresis on Skin Integrity in Human Volunteers I. Methodology and Reproducibility

1996 • 19 citations

Deleted Work

1955 • 0 citations