Pharmacokinetics of Adenoviral Vector-Mediated Gene Delivery to Vascular Smooth Muscle Cells: Modulation by Poloxamer 407 and Implications for Cardiovascular Gene Therapy

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Mathematical Theory of the Kinetics of the Coagulation of Colloidal Solutions

1917 • 2,816 citations

Integrins αvβ3 and αvβ5 promote adenovirus internalization but not virus attachment

1993 • 2,182 citations

In vivo transfer of the human cystic fibrosis transmembrane conductance regulator gene to the airway epithelium

1992 • 953 citations

Antisense c-myb oligonucleotides inhibit intimal arterial smooth muscle cell accumulation in vivo

1992 • 749 citations

Adenovirus-Mediated Transfer of a Recombinant α1-Antitrypsin Gene to the Lung Epithelium in Vivo

1991 • 743 citations

A model system for in vivo gene transfer into the central nervous system using an adenoviral vector

1993 • 588 citations

Methods for Studying Mononuclear Phagocytes

1981 • 576 citations

Site-Specific Gene Expression in Vivo by Direct Gene Transfer into the Arterial Wall

1990 • 573 citations

Recombinant Gene Expression in Vivo Within Endothelial Cells of the Arterial Wall

1989 • 445 citations

Role of diffusion in ligand binding to macromolecules and cell-bound receptors

1982 • 412 citations

Improved Methods of Retroviral Vector Transduction and Production for Gene Therapy

1994 • 382 citations

Adenovirus mediated expression of therapeutic plasma levels of human factor IX in mice

1993 • 345 citations

Virus-Receptor Interaction in an Adenovirus System

1968 • 343 citations

Implantation of Vascular Grafts Lined with Genetically Modified Endothelial Cells

1989 • 342 citations

Seeding of intravascular stents with genetically engineered endothelial cells.

1989 • 328 citations

Evaluation of the Transfer and Expression in Mice of an Enzyme-Encoding Gene Using a Human Adenovirus Vector

1990 • 325 citations

Direct gene transfer of human CFTR into human bronchial epithelia of xenografts with E1–deleted adenoviruses

1993 • 303 citations

Image reconstruction reveals the complex molecular organization of adenovirus

1991 • 284 citations

Effect of controlled adventitial heparin delivery on smooth muscle cell proliferation following endothelial injury.

1990 • 256 citations

Human adenovirus-host cell interactions: comparative study with members of subgroups B and C

1990 • 248 citations

Safety and efficacy of repetitive adenovirus–mediated transfer of CFTR cDNA to airway epithelia of primates and cotton rats

1994 • 216 citations

In vivo adenoviral vector-mediated gene transfer into balloon-injured rat carotid arteries.

1993 • 210 citations

Long–term correction of mouse dystrophic degeneration by adenovirus–mediated transfer of a minidystrophin gene

1993 • 201 citations

Diversity of airway epithelial cell targets for in vivo recombinant adenovirus-mediated gene transfer.

1993 • 199 citations

The Plaque Assay of Animal Viruses

1962 • 188 citations

Adenovirus-mediated gene transfer for cystic fibrosis: quantitative evaluation of repeated in vivo vector administration to the lung.

1994 • 188 citations

Adenoviral-mediated gene transfer to rabbit synovium in vivo.

1993 • 186 citations

Adenovirus-mediated transfer of a recombinant human alpha 1-antitrypsin cDNA to human endothelial cells.

1992 • 180 citations

In VivoEvaluation of the Safety of Adenovirus-Mediated Transfer of the Human Cystic Fibrosis Transmembrane Conductance Regulator cDNA to the Lung

1994 • 177 citations

The polyoxyethylene/polyoxypropylene block co‐polymer Poloxamer‐407 selectively redirects intravenously injected microspheres to sinusoidal endothelial cells of rabbit bone marrow

1992 • 172 citations

Sustained delivery of interleukin-2 from a poloxamer 407 gel matrix following intraperitoneal injection in mice.

1992 • 163 citations

Low level in vivo gene transfer into the arterial wall through a perforated balloon catheter.

1992 • 159 citations

Anatomic barriers influence the distribution of in vivo gene transfer into the arterial wall. Modeling with microscopic tracer particles and verification with a recombinant adenoviral vector.

1994 • 154 citations

An approach for treating the hepatobiliary disease of cystic fibrosis by somatic gene transfer.

1993 • 146 citations

Direct in vivo gene transfer into the coronary and peripheral vasculatures of the intact dog.

1991 • 144 citations

Biological Activity of Urease Formulated in Poloxamer 407 after Intraperitoneal Injection in the Rat

1992 • 134 citations

Percutaneous arterial gene transfer in a rabbit model. Efficiency in normal and balloon-dilated atherosclerotic arteries.

1992 • 125 citations

Syringe loading introduces macromolecules into living mammalian cell cytosol

1992 • 121 citations

Virus particle adsorption I. Theory of adsorption and experiments on the attachment of particles to non-biological surfaces

1959 • 117 citations

General analysis of receptor-mediated viral attachment to cell surfaces

1990 • 112 citations

Adenoviral vectors for gene transfer

1993 • 99 citations

Sterie stabilization of microspheres with grafted polyethylene oxide reduces phagocytosis by rat Kupffer cells in vitro

1991 • 93 citations

Saturable binding sites for vesicular stomatitis virus on the surface of Vero cells

1982 • 89 citations

Virus particle adsorption

1960 • 84 citations

Evaluation of the Efficacy and Safety ofIn Vitro, Adenovirus-Mediated Transfer of the Human Cystic Fibrosis Transmembrane Conductance Regulator cDNA

1994 • 80 citations

Host-cell interaction of animal viruses

1958 • 70 citations

Changes in intracellular free calcium concentration during long exposures to simulated ischemia in isolated mammalian ventricular muscle.

1992 • 67 citations

Equilibrium and kinetic analysis of Autographa californica nuclear polyhedrosis virus attachment to different insect cell lines

1992 • 65 citations

Influence of the surface properties of low contact angle surfactants on the body distribution of¹⁴C-poly(methyl methacrylate) nanoparticles

1992 • 59 citations

Virus particle adsorption

1960 • 55 citations

Virus receptor interaction in the adenovirus system. II. Capping and cooperative binding of virions on HeLa cells

1983 • 53 citations

On the two-step nature of bacteriophage adsorption

1952 • 53 citations

Human cytomegalovirus binding to fibroblasts is receptor mediated

1989 • 48 citations

Effects of thiol protease inhibitors on cell cycle and proliferation of vascular smooth muscle cells in culture.

1993 • 40 citations

Encounter efficiency of coliphage-bacterium interaction

1960 • 39 citations

Expression and modulation of virus receptors on lymphoid and myeloid cells: Relationship to infectivity

1982 • 35 citations

Biodegradable microspheres containing a colchicine analogue inhibit DNA synthesis in vascular smooth muscle cells.

1994 • 27 citations

Pluronic micelles as a tool for low-molecular compound vector delivery into a cell: effect of Staphylococcus aureus enterotoxin B on cell loading with micelle incorporated fluorescent dye.

1992 • 25 citations

Developmental failure of chimeric embryos expressing high levels of H-2Dd transplantation antigens.

1992 • 23 citations

Giant pseudopolyposis in granulomatous colitis

1979 • 12 citations

X-ray photoelectron spectroscopy analysis of the surface chemical structure of some biodegradable poly (orthoesters)

1991 • 8 citations

Human enteric adenovirus type 41 binding to HEp-2 cells is specific

1991 • 7 citations

Phage-cell binding in external electric fields and in viscous media

1960 • 3 citations