Acute inflammatory response in the mouse: exacerbation by immunoneutralization of lipocortin 1

Immunoregulatory Feedback Between Interleukin-1 and Glucocorticoid Hormones

1986 • 1,521 citations

Interleukin-1 Stimulates the Secretion of Hypothalamic Corticotropin-Releasing Factor

1987 • 1,512 citations

The production of cytokines by polymorphonuclear neutrophils

1995 • 918 citations

Endogenous glucocorticoids regulate an inducible cyclooxygenase enzyme.

1992 • 471 citations

Lipocortin-1: cellular mechanisms and clinical relevance

1994 • 383 citations

Statistics: Theory and Methods

1991 • 278 citations

Modulation of IL-1-induced neutrophil migration by dexamethasone and lipocortin 1.

1993 • 223 citations

Human recombinant lipocortin 1 has acute local anti-inflammatory properties in the rat paw edema test.

1989 • 204 citations

Anti-inflammatory lipocortin 1 production by peripheral blood leucocytes in response to hydrocortisone

1990 • 186 citations

Lipocortin-1 fragments inhibit neutrophil accumulation and neutrophil-dependent edema in the mouse. A qualitative comparison with an anti-CD11b monoclonal antibody.

1993 • 167 citations

Presence of autoantibody for phospholipase inhibitory protein, lipomodulin, in patients with rheumatic diseases.

1981 • 157 citations

A comparative study of the cellular, exudative and histological responses to carrageenan, dextran and zymosan in the mouse.

1991 • 154 citations

Amino acid sequence analysis of the annexin super‐gene family of proteins

1991 • 152 citations

Lipocortin 1 mediates dexamethasone-induced growth arrest of the A549 lung adenocarcinoma cell line.

1992 • 140 citations

Lipocortin 1 mediates the inhibition by dexamethasone of the induction by endotoxin of nitric oxide synthase in the rat.

1995 • 139 citations

Lipocortin-1 is an endogenous inhibitor of ischemic damage in the rat brain.

1991 • 134 citations

Leukocyte transmigration, but not rolling or adhesion, is selectively inhibited by dexamethasone in the hamster post-capillary venule. Involvement of endogenous lipocortin 1.

1995 • 131 citations

In vivo glucocorticoids regulate cyclooxygenase-2 but not cyclooxygenase-1 in peritoneal macrophages.

1994 • 125 citations

Inhibition of O2- generation by dexamethasone is mimicked by lipocortin I in alveolar macrophages.

1989 • 108 citations

Lipocortin 1 Mediates an Early Inhibitory Action of Glucocorticoids on the Secretion of ACTH by the Rat Anterior Pituitary Gland in vitro

1993 • 100 citations

Role of lipocortin I in the glucocorticoid induction of the terminal differentiation of a human squamous carcinoma

1990 • 99 citations

A possible role of airway epithelium in modulating hyperresponsiveness

1988 • 92 citations

Lipocortin I (p35) is abundant in a restricted number of differentiated cell types in adult organs

1989 • 87 citations

A comparison of the acute inflammatory response in adrenalectomised and sham‐operated rats

1986 • 78 citations

Sarcomere dynamics during isotonic velocity transients in single frog muscle fibers

1990 • 78 citations

Antipyretic actions of human recombinant lipocortin‐1

1991 • 71 citations

Autoantibodies to recombinant lipocortin-1 in rheumatoid arthritis and systemic lupus erythematosus.

1989 • 64 citations

Dexamethasone‐induced translocation of lipocortin (annexin) 1 to the cell membrane of U‐937 cells

1994 • 62 citations

Lipocortin 1 fragment modifies pyrogenic actions of cytokines in rats

1990 • 60 citations

Studies on the structural properties of lipocortin-1 and the regulation of its synthesis by steroids.

1990 • 58 citations

Selective inhibition of neutrophil function by a peptide derived from lipocortin 1 N-terminus

1995 • 56 citations

Early Biochemical Events in Leukocyte Activation

1989 • 53 citations

Evidence that endogenous interleukin-1 is involved in leukocyte migration in acute experimental inflammation in rats and mice

1992 • 52 citations

Lipocortin-derived peptides

1994 • 49 citations

The local anti‐inflammatory action of dexamethasone in the rat carrageenin oedema model is reversed by an antiserum to lipocortin 1

1993 • 48 citations

Interaction between neutrophil-derived elastase and reactive oxygen species in cartilage degradation

1993 • 45 citations

Serum corticosterone, interleukin‐1 and tumour necrosis factor in rat experimental endotoxaemia: comparison between Lewis and Wistar strains

1993 • 44 citations

Immunoneutralization of Lipocortin 1 Reverses the Acute Inhibitory Effects of Dexamethasone on the Hypothalamo-Pituitary-Adrenocortical Responses to Cytokines in the Rat in vitro and in vivo

1995 • 43 citations

Effect of rolipram in a murine model of acute inflammation: comparison with the corticoid dexamethasone

1995 • 40 citations

Statistics: Theory and Methods.

1990 • 34 citations

Effects of Lipocortin 1 and Dexamethasone on the Secretion of Corticotrophin‐Releasing Factors in the Rat: in vitro and in vivo Studies

1993 • 33 citations

Circulating group II phospholipase A2 activity and antilipocortin antibodies in systemic lupus erythematosus. Correlative study with disease activity.

1994 • 33 citations

The effect of adrenalectomy on interleukin‐1 release in vitro and in vivo

1989 • 30 citations

Antibodies to Human Recombinant Lipocortin-L in Inflammatory Bowel Disease

1993 • 22 citations

Impaired febrile responses of aging mice are mediated by endogenous lipocortin-1 (annexin-1)

1993 • 21 citations

Endogenous corticosteroids mediate the neutrophilia caused by platelet-activating factor in the mouse

1995 • 16 citations

Anti-inflammatory effect of prostanoids in mouse and rat skin: evidence for a role of EP3-receptors.

1994 • 16 citations

Lack of involvement of lipocortin 1 in dexamethasone suppression of IL‐1 release

1992 • 4 citations

Deleted Work

1955 • 0 citations