Back to search

Increased Anxiety‐Like Behavior and Ethanol Self‐Administration in Dependent Rats: Reversal via Corticotropin‐Releasing Factor‐2 Receptor Activation

Data up to Jan 2025

Published2004
Citations132
References69

Total Citations Per Year

Abstract

References (69)

Lifetime and 12-Month Prevalence of DSM-III-R Psychiatric Disorders in the United States

1994 • 12,456 citations

A stereotaxic atlas of the rat brain

1967 • 4,710 citations

Characterization of a 41-Residue Ovine Hypothalamic Peptide that Stimulates Secretion of Corticotropin and β-Endorphin

1982 • 3,896 citations

Guide for the care and use of laboratory animals

1997 • 3,181 citations

A stereotaxic atlas of the rat brain

1980 • 2,782 citations

Neurogenetic Adaptive Mechanisms in Alcoholism

1987 • 2,300 citations

Lifetime Co-occurrence of DSM-III-R Alcohol Abuse and Dependence With Other Psychiatric Disorders in the National Comorbidity Survey

1997 • 2,048 citations

Urocortin, a mammalian neuropeptide related to fish urotensin I and to corticotropin-releasing factor

1995 • 1,469 citations

Physiological and behavioral responses to corticotropin-releasing factor administration: is CRF a mediator of anxiety or stress responses?

1990 • 1,362 citations

Distribution of mRNAs encoding CRF receptors in brain and pituitary of rat and mouse

2000 • 1,029 citations

Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1

1998 • 919 citations

Localization of novel corticotropin-releasing factor receptor (CRF2) mRNA expression to specific subcortical nuclei in rat brain: comparison with CRF1 receptor mRNA expression

1995 • 917 citations

Corticotropin Releasing Factor Receptor 1–Deficient Mice Display Decreased Anxiety, Impaired Stress Response, and Aberrant Neuroendocrine Development

1998 • 883 citations

Urocortin II: A member of the corticotropin-releasing factor (CRF) neuropeptide family that is selectively bound by type 2 CRF receptors

2001 • 877 citations

Mice deficient for corticotropin-releasing hormone receptor-2 display anxiety-like behaviour and are hypersensitive to stress

2000 • 836 citations

Cloning and characterization of a functionally distinct corticotropin-releasing factor receptor subtype from rat brain.

1995 • 836 citations

Ethopharmacological analysis of rat behavior on the elevated plus-maze

1994 • 823 citations

Alcoholism: Allostasis and Beyond

2003 • 738 citations

Initiation of Ethanol Reinforcement using a Sucrose‐Substitution Procedure in Food‐ and Water‐Sated Rats

1986 • 668 citations

Increase of extracellular corticotropin-releasing factor-like immunoreactivity levels in the amygdala of awake rats during restraint stress and ethanol withdrawal as measured by microdialysis

1995 • 568 citations

Appetite-Suppressing Effects of Urocortin, a CRF-Related Neuropeptide

1996 • 561 citations

Intraventricular corticotropin-releasing factor enhances behavioral effects of novelty

1982 • 536 citations

Deletion of Crhr2 reveals an anxiolytic role for corticotropin-releasing hormone receptor-2

2000 • 490 citations

Kindling as a Model for Alcohol Withdrawal Syndromes

1978 • 470 citations

Changes in depression among abstinent alcoholics.

1988 • 420 citations

Microinjection of a corticotropin-releasing factor antagonist into the central nucleus of the amygdala reverses anxiogenic-like effects of ethanol withdrawal

1993 • 411 citations

Modulation of Learning and Anxiety by Corticotropin-Releasing Factor (CRF) and Stress: Differential Roles of CRF Receptors 1 and 2

1999 • 405 citations

Alcohol dependence and anxiety disorders: what is the relationship?

1994 • 394 citations

Increased Ethanol Self‐Administration and Anxiety‐Like Behavior During Acute Ethanol Withdrawal and Protracted Abstinence: Regulation by Corticotropin‐Releasing Factor

2002 • 386 citations

Chemical and Biological Characterization of Corticotropin Releasing Factor

1983 • 375 citations

CRF antagonist reverses the “anxiogenic” response to ethanol withdrawal in the rat

1991 • 357 citations

Urocortin Expression in Rat Brain: Evidence Against a Pervasive Relationship of Urocortin-Containing Projections With Targets Bearing Type 2 CRF Receptors

1999 • 354 citations

Excessive Ethanol Drinking Following a History of Dependence Animal Model of Allostasis

2000 • 348 citations

Intra‐amygdala Muscimol Decreases Operant Ethanol Self‐administration in Dependent Rats

1996 • 346 citations

Corticotropin-Releasing Factor*

1982 • 326 citations

The role of corticotrophin-releasing factor in stress-induced relapse to alcohol-seeking behavior in rats

2000 • 314 citations

Repeated Episodes of Ethanol Withdrawal Potentiate the Severity of Subsequent Withdrawal Seizures: An Animal Model of Alcohol Withdrawal “Kindling”

1993 • 284 citations

Urocortin III-Immunoreactive Projections in Rat Brain: Partial Overlap with Sites of Type 2 Corticotrophin-Releasing Factor Receptor Expression

2002 • 240 citations

The Impact of the Nonpeptide Corticotropin-Releasing Hormone Antagonist Antalarmin on Behavioral and Endocrine Responses to Stress**This research was supported by NIMH Grant MH-50479 and the Undergraduate Research Opportunities Program at the University of Colorado at Boulder.

1999 • 238 citations

Stress, Corticotropin‐releasing Factor, and Drug Addiction

1999 • 226 citations

Reduced anxiety-like and cognitive performance in mice lacking the corticotropin-releasing factor receptor 11Published on the World Wide Web on 27 November 1998.1

1999 • 224 citations

Characterization of the behavioral profile of the non-peptide CRF receptor antagonist CP-154,526 in anxiety models in rodents

1998 • 205 citations

Neurobiology of corticotropin releasing factor (CRF) receptors and CRF-binding protein: implications for the treatment of CNS disorders.

1996 • 187 citations

High-priority communication I Antagonism of corticotropin-releasing factor attenuates the enhanced responsiveness to stress observed during protracted ethanol abstinence

2003 • 185 citations

Time-dependent quantifiable withdrawal from ethanol in the rat: Effect of method of dependence induction

1996 • 168 citations

Effects of antalarmin, a CRF type 1 receptor antagonist, on anxiety-like behavior and motor activation in the rat

2002 • 154 citations

Comorbidity in Generalized Anxiety Disorder

2001 • 142 citations

Anti-Stress Action of a Corticotropin-Releasing Factor Antagonist on Behavioral Reactivity to Stressors of Varying Type and Intensity

1994 • 142 citations

Locomotor suppressive and anxiolytic-like effects of urocortin 3, a highly selective type 2 corticotropin-releasing factor agonist

2003 • 141 citations

Human urocortin II: mild locomotor suppressive and delayed anxiolytic-like effects of a novel corticotropin-releasing factor related peptide

2002 • 141 citations

Alcohol withdrawal symptoms and drinking behavior.

1977 • 140 citations

Corticotropin releasing factor, stress and behavior

1994 • 139 citations

Lateral and medial septal lesions reduce anxiety in the plus-maze and probe-burying tests

1996 • 136 citations

Repeated ethanol withdrawal experience increases the severity and duration of subsequent withdrawal seizures in mice

1997 • 126 citations

Positive relationship between the number of prior ethanol withdrawal episodes and the severity of subsequent withdrawal seizures

1994 • 111 citations

The Edinger-Westphal–Lateral Septum Urocortin Pathway and Its Relationship to Alcohol Consumption

2003 • 106 citations

The role of the lateral septum in anxiolysis

1993 • 102 citations

Operant Self-Administration of Sweetened Versus Unsweetened Ethanol: Effects on Blood Alcohol Levels

1999 • 98 citations

Chronic Daily Ethanol and Withdrawal: 2. Behavioral Changes During Prolonged Abstinence

2001 • 95 citations

Effects of Chronic Ethanol Exposure on Oral Self‐Administration of Ethanol or Saccharin by Wistar Rats

1996 • 90 citations

The Fawn-Hooded (FH/Wjd) rat: a genetic animal model of comorbid depression and alcoholism

2002 • 87 citations

Human Urocortin II, a Selective Agonist for the Type 2 Corticotropin-Releasing Factor Receptor, Decreases Feeding and Drinking in the Rat

2003 • 84 citations

Altered Amygdalar CRF Release and Increased Anxiety‐Like Behavior in Sardinian Alcohol‐Preferring Rats: A Microdialysis and Behavioral Study

2000 • 83 citations

The CRF1 receptor antagonist antalarmin reduces volitional ethanol consumption in isolation-reared fawn-hooded rats

2003 • 72 citations

Exacerbation of Ethanol Withdrawal Seizures in Mice With a History of Multiple Withdrawal Experience

1997 • 66 citations

Alcohol increases the expression of type 1, but not type 2α corticotropin-releasing factor (CRF) receptor messenger ribonucleic acid in the rat hypothalamus

1997 • 64 citations

Chronic ethanol exposure potentiates the locomotor-activating effects of corticotropin-releasing factor (CRF) in rats

1987 • 39 citations

Posterodorsal amygdala lesions reduce feeding stimulated by 8-OH-DPAT

2000 • 25 citations

Alcohol Withdrawal Symptoms: Phenomenology and Implications

1973 • 15 citations

Cited By (0)

Loading...