Involvement of phospholipase A2 activation in tumour cell killing by tumour necrosis factor.

An endotoxin-induced serum factor that causes necrosis of tumors.

1975 • 4,522 citations

ARACHIDONIC ACID METABOLISM

1986 • 1,802 citations

Recombinant Human Tumor Necrosis Factor-α: Effects on Proliferation of Normal and Transformed Cells in Vitro

1985 • 1,596 citations

Cachectin: More Than a Tumor Necrosis Factor

1987 • 1,457 citations

Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts.

1985 • 1,240 citations

Comparison of in vitro cell cytotoxic assays for tumor necrosis factor

1984 • 752 citations

Fibroblast growth enhancing activity of tumor necrosis factor and its relationship to other polypeptide growth factors.

1986 • 674 citations

Amplification of specific DNA sequences correlates with multi-drug resistance in Chinese hamster cells

1984 • 340 citations

Renal cytochrome P450-related arachidonate metabolite inhibits (Na+ + K+)ATPase

1985 • 314 citations

Liver microsomal cytochrome P-450 and the oxidative metabolism of arachidonic acid.

1981 • 295 citations

Polypetide mediator network

1987 • 200 citations

Recombinant tumor necrosis factor and intepleukin-1 both stimulate human synovial cell arachidonic acid release and phospholipid metabolism

1987 • 110 citations

Antifolate-resistant Chinese Hamster Cells. mRNA directed overproduction of multiple dihydrofolate reductases from a series of independently derived sublines containing amplified dihydrofolate reductase genes.

1982 • 38 citations

Conversion of arachidonic acid to two novel products by a cytochrome P450-dependent mixed-function oxidase in polymorphonuclear leukocytes

1984 • 28 citations