Comment on "PDK1 Nucleates T Cell Receptor-Induced Signaling Complex for NF-κB Activation"
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Abstract
References (10)
Regulation of the ABC kinases by phosphorylation: protein kinase C as a paradigm
2003 • 791 citations
Protein Kinase C θ Affects Ca2+ Mobilization and NFAT Activation in Primary Mouse T Cells
2003 • 320 citations
PDK1 Nucleates T Cell Receptor-Induced Signaling Complex for NF-κB Activation
2005 • 249 citations
Emerging and diverse roles of protein kinase C in immune cell signalling
2003 • 248 citations
Protein Kinase C θ Is Critical for the Development of In Vivo T Helper (Th)2 Cell But Not Th1 Cell Responses
2004 • 202 citations
Catalytic Domain Crystal Structure of Protein Kinase C-θ (PKCθ)
2004 • 135 citations
The PKC gene module: molecular biosystematics to resolve its T cell functions
2003 • 134 citations
Phosphorylation of the protein kinase C-theta activation loop and hydrophobic motif regulates its kinase activity, but only activation loop phosphorylation is critical to in vivo nuclear-factor-κB induction
2002 • 123 citations
Site-directed mutagenesis reveals a novel catalytic mechanism of Mycobacterium tuberculosis alkylhydroperoxidase C
2002 • 62 citations
Critical role of novel Thr-219 autophosphorylation for the cellular function of PKCθ in T lymphocytes
2005 • 52 citations