Nonstereoselective aspects of propranolol pharmacodynamics

Approaches to Sudden Death from Coronary Heart Disease

1971 • 1,258 citations

The biological properties of the optical isomers of propranolol and their effects on cardiac arrhythmias

1968 • 562 citations

Animal models for the study of anti-anxiety agents: A review

1985 • 457 citations

THE EFFECTS ON CARDIAC MUSCLE OF β‐RECEPTOR ANTAGONISTS IN RELATION TO THEIR ACTIVITY AS LOCAL ANAESTHETICS

1965 • 248 citations

Effect of propranolol on platelet function

1977 • 233 citations

Reversal of Abnormal Platelet Aggregability and Change in Exercise Tolerance in Patients with Angina Pectoris Following Oral Propranolol

1974 • 183 citations

Some effects of propranolol on the central nervous system

1965 • 159 citations

Effects of Cyclic AMP, Sympathomimetic Amines, and Adrenergic Receptor Antagonists on Renin Secretion

1971 • 132 citations

Brain concentration of propranolol in relation to hypotensive effect in the rabbit with observations on brain propranolol levels in man.

1975 • 132 citations

ANTI-PLATELET ACTIVITY OF BETA-ADRENERGIC ANTAGONISTS: INHIBITION OF THROMBOXANE SYNTHESIS AND PLATELET AGGREGATION IN PATIENTS RECEIVING LONG-TERM PROPRANOLOL TREATMENT

1981 • 119 citations

THE EFFECTS OF PRONETHALOL AND ITS DEXTRO ISOMER UPON EXPERIMENTAL CARDIAC ARRHYTHMIAS.

1965 • 118 citations

EFFECT OF ADRENERGIC β-BLOCKADE ON PARKINSONIAN TREMOR

1965 • 105 citations

Central Hypotensive Activity of dl- and d-Propranolol

1970 • 103 citations

ANTIARRHYTHMIC EFFECTS OF BETA ADRENERGIC BLOCKING AGENTS*

1967 • 93 citations

Studies on the uptake and binding of propranolol by rat tissues.

1977 • 92 citations

Propranolol and experimental myocardial infarction: substrate effects.

1976 • 74 citations

Inotropie and Chronotropic Effects of a Series of -Adrenergic Blocking Drugs: Some Structure-Activity Relationships.

1966 • 72 citations

THE PERIPHERAL VASCULAR EFFECTS OF PROPRANOLOL AND RELATED COMPOUNDS

1967 • 68 citations

D-PROPRANOLOL AND ANXIETY

1971 • 66 citations

D-propranolol and DL-propranolol both decrease conversion of L-thyroxine to L-triiodothyronine.

1980 • 65 citations

β-Adrenergic receptors in human platelets

1969 • 62 citations

Effect of propranolol upon the hemoglobin-oxygen dissociation curve.

1972 • 61 citations

Propranolol‐induced airway hyperreactivity in guinea‐pigs

1983 • 60 citations

Steric aspects of adrenergic drugs. 8. Optical isomers of beta adrenergic receptor antagonists.

1968 • 52 citations

INVESTIGATION OF THE MECHANISM OF PROPRANOLOL‐INDUCED BRONCHOCONSTRICTION

1979 • 52 citations

ROLE OF CENTRAL β‐ADRENOCEPTORS IN THE CONTROL OF PENTYLENETETRAZOL‐INDUCED CONVULSIONS IN RATS

1982 • 47 citations

Inhibition by Propranolol of 3,5,3′-Triiodothyronine Formation from Thyroxine in Isolated Rat Renal Tubules: An Effect Independent ofβ-Adrenergic Blockade

1980 • 46 citations

Effect of dl- and d-propranolol on ocular tension in rabbits and patients

1970 • 45 citations

Effects of beta receptor stimulation and blockade on A-V nodal and bundle branch conduction in the canine heart

1973 • 42 citations

Effects of propranolol therapy on platelet release and prostaglandin generation in patients with coronary heart disease.

1982 • 39 citations

Continous, simultaneous, and instant display of aqueous humor dynamics with a micro-spectrophotometer and a sensitive drop counter

1981 • 38 citations

Central hypotensive effect of propranolol in the rabbit.

1973 • 38 citations

Inhibitory Action of Adrenergic Blocking Agents on Reuptake and Net Uptake of Noradrenaline in Nerve Granules

1968 • 37 citations

Inhibitory effect of propranolol on the vasoconstrictor response to sympathetic nerve stimulation

1970 • 36 citations

Comparative studies on central factors contributing to the hypotensive action of propranolol, alprenolol, and their enantiomers

1974 • 35 citations

Influence of propranolol isomers and atenolol on myocardial cyclic AMP, high energy phosphates and vulnerability to fibrillation after coronary artery ligation in the isolated rat heart

1981 • 32 citations

Enhancement of Electrical Stability of Acutely Ischemic Myocardium by Edrophonium

1974 • 29 citations

THE EFFECTS OF (+)‐ AND (–)‐PROPRANOLOL ON ³H‐TRANSMITTER EFFLUX IN GUINEA‐PIG ATRIA AND THE PRESYNAPTIC β‐ADRENOCEPTOR HYPOTHESIS

1980 • 28 citations

The anticonvulsant effects of propranolol and β-adrenergic blockade

1979 • 27 citations

The effect of the dextro isomer of propranolol on sinus rate and cardiac arrhythmias

1968 • 26 citations

CHARACTERIZATION OF RECEPTORS MEDIATING 5‐HYDROXYTRYPTAMINE‐ AND CATECHOLAMINE‐INDUCED PLATELET AGGREGATION, ASSESSED BY THE ACTIONS OF α‐ AND β‐BLOCKERS, BUTYROPHENONES, 5‐HT ANTAGONISTS AND CHLORPROMAZINE

1978 • 26 citations

Effect of Different β‐Adrenergic Receptor Blocking Agents on Hexobarbital Induced Narcosis in Mice

1969 • 25 citations

Propranolol and beta‐adrenergic receptor blocking drugs in the treatment of hypertension.

1982 • 24 citations

The effect of β‐adrenoceptor blocking agents, with differing ancillary properties, on the arrhythmias resulting from acute coronary artery ligation in anaesthetized rats

1983 • 22 citations

Influence of beta‐adrenoceptor blocking agents on lymphocyte function in vitro.

1982 • 17 citations

Studies on the inhibition by propranolol of some human erythrocyte membrane enzymes and plasma cholinesterase

1982 • 16 citations

Contractile actions of racemic and d-propranolol on isolated canine mesenteric and coronary arteries.

1982 • 15 citations

Adrenergic modulation of gastric stress pathology in rats: a cholinergic link

1987 • 15 citations

Effects of (±)‐propranolol, (±)‐, (+)‐, and (–)‐alprenolol on unanaesthetized dogs with ventricular arrhythmias resulting from coronary artery ligation

1970 • 10 citations

COMPARATIVE STUDIES OF (−)‐, (±), (+)‐PROPRANOLOL, ATENOLOL, GUANETHIDINE, BRETYLIUM AND TETRACAINE ON ADRENERGIC TRANSMISSION

1981 • 9 citations

Is the hypotensive effect obtained by application of drugs to the ventral surface of the brain stem due to a membrane stabilizing mechanism? A study with beta-blockers

1978 • 9 citations

Antioxytocin activity of propranolol, INPEA and their optical isomers on the isolated rat uterus

1971 • 9 citations

Studies on the effect of physostigmine on experimental cardiac arrhythmias in dogs

1972 • 9 citations

Effects of d- and l-propranolol on the responsiveness of human fibroblasts to choleragen and prostaglandin E1

1981 • 8 citations

Electrocardiographic surface mapping of the heart following myocardial infarction and the influence of beta-blockade.

1976 • 8 citations

Effects of the optical isomers of propranolol on neuromuscular transmission in the rat

1978 • 8 citations

The effect of sympatholytic and sympathomimetic agents on acetylcholinesterase and cholinesterase activity, in vitro

1976 • 8 citations

External cardiac excitation as a cause of ventricular fibrillation during hypothermia and its prevention by acetylcholine.

1960 • 5 citations

Comparative effects of (+)- and (−)-isomers of propranolol and inpea on (+)-tubocurarine- and succinylcholine-induced neuromuscular blockade

1975 • 4 citations