Properties and Kinetic Analysis of UDP-glucose Dehydrogenase from Group A Streptococci

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

The kinetics of enzyme-catalyzed reactions with two or more substrates or products☆I. Nomenclature and rate equations

1963 • 2,095 citations

The kinetics of enzyme-catalyzed reactions with two or more substrates or products

1963 • 1,885 citations

The kinetics of enzyme-catalyzed reactions with two or more substrates or products

1963 • 836 citations

Developments in Biological Standardization

1993 • 617 citations

The kinetics of enzyme-catalyzed reactions with two or more substrates or products☆III. Prediction of initial velocity and inhibition patterns by inspection

1963 • 516 citations

ENZYMATIC FORMATION OF URIDINE DIPHOSPHOGLUCURONIC ACID

1957 • 351 citations

The Role of Bacterial Polysaccharide Capsules as Virulence Factors

1990 • 284 citations

Characterization of the cassette containing genes for type 3 capsular polysaccharide biosynthesis in Streptococcus pneumoniae.

1995 • 152 citations

Investigation of the Active Site Cysteine Residue of Rat Liver Mitochondrial Aldehyde Dehydrogenase by Site-Directed Mutagenesis

1995 • 149 citations

Hyaluronic Acid Synthesis Operon (has) Expression in Group A Streptococci

1995 • 134 citations

Interruption of capsule production in Streptococcus pneumonia serotype 3 by insertion of transposon Tn916

1990 • 134 citations

Molecular Characterization of hasC from an Operon Required for Hyaluronic Acid Synthesis in Group A Streptococci DEMONSTRATION OF UDP-GLUCOSE PYROPHOSPHORYLASE ACTIVITY

1995 • 131 citations

Virulence, Immunity, and Vaccine Related to Streptococcus pneumoniae

1991 • 119 citations

Effects on virulence of mutations in a locus essential for hyaluronic acid capsule expression in group A streptococci

1994 • 117 citations

The Biologic Significance of Bacterial Encapsulation

1990 • 112 citations

Molecular characterization of hasB from an operon required for hyaluronic acid synthesis in group A streptococci. Demonstration of UDP-glucose dehydrogenase activity.

1993 • 98 citations

Molecular characterization of cap3A, a gene from the operon required for the synthesis of the capsule of Streptococcus pneumoniae type 3: sequencing of mutations responsible for the unencapsulated phenotype and localization of the capsular cluster on the pneumococcal chromosome

1994 • 88 citations

Region 2 of the Escherichia coli K5 capsule gene cluster encoding proteins for the biosynthesis of the K5 polysaccharide

1995 • 80 citations

Haloacetol phosphates. Potential active-site reagents for aldolase, triose phosphate isomerase, and glycerophosphate dehydrogenase. I. Preparation and properties

1970 • 71 citations

UDP‐glucose dehydrogenase from bovine liver: Primary structure and relationship to other dehydrogenases

1994 • 60 citations

Mechanism of action of uridine diphosphoglucose dehydrogenase. Evidence for a second reversible dehydrogenation step involving an essential thiol group.

1975 • 55 citations

The Mechanism of Action of Uridine Diphosphoglucose Dehydrogenase

1971 • 50 citations

Factors that influence the translocation of the N-carboxybiotin moiety between the two sub-sites of pyruvate carboxylase

1981 • 47 citations

Mechanism of action of uridine diphoglucose dehydrogenase. Evidence for an essential lysine residue at the active site.

1977 • 47 citations

Partial purification and properties of UDPG dehydrogenase from Escherichia coli

1973 • 40 citations

A study of the subunit structure and the thiol reactivity of bovine liver uridine diphosphate glucose dehydrogenase

1972 • 39 citations

Mechanisms of action of histidinol dehydrogenase and UDP-Glc dehydrogenase. Evidence that the half-reactions proceed on separate subunits.

1979 • 38 citations

Udpglucose dehydrogenase Kinetics and their mechanistic implications

1977 • 36 citations

Expression and characterization of UDPGlc dehydrogenase (KfiD), which is encoded in the type-specific region 2 of the Escherichia coli K5 capsule genes

1995 • 36 citations

Demonstration of UDP-glucose dehydrogenase activity in cell extracts of Escherichia coli expressing the pneumococcal cap3A gene required for the synthesis of type 3 capsular polysaccharide

1996 • 35 citations

UDP-Glucose dehydrogenase from escherichia coli

1976 • 32 citations

10 Mechanism of NAD-Dependent Enzymes

1992 • 30 citations

Resonance energy transfer between catalytic sites of bovine liver uridine diphosphoglucose dehydrogenase

1980 • 29 citations

Amino acid sequence of the tryptic peptide containing the catalytic-site thiol group of bovine liver uridine diphosphate glucose dehydrogenase

1981 • 28 citations

Induced versus pre-existing asymmetry models for the half-of-the-sites reactivity effect in bovine liver uridine diphosphoglucose dehydrogenase

1980 • 27 citations

Involvement of cysteine 289 in the catalytic activity of an NADP+-specific fatty aldehyde dehydrogenase from Vibrio harveyi

1995 • 27 citations

Steady-state investigations of the mechanism of histidinol dehydrogenase

1979 • 26 citations

Conserved cysteine residues of histidinol dehydrogenase are not involved in catalysis. Novel chemistry required for enzymatic aldehyde oxidation

1993 • 24 citations

A new chemical mechanism catalyzed by a mutated aldehyde dehydrogenase

1992 • 24 citations

Overexpression, one-step purification and characterization of UDP-glucose dehydrogenase and UDP-N-acetylglucosamine pyrophosphorylase

1996 • 20 citations

Patterns of Product Inhibition of a Bifunctional Dehydrogenase; <scp>l</scp>‐Histidinol : NAD⁺ Oxidoreductase

1981 • 20 citations

Half-of-the-sites reactivity of bovine liver uridine diphosphoglucose dehydrogenase toward iodoacetate and iodoacetamide

1976 • 19 citations

Cysteine residue (cysteine-116) in the histidinol binding site of histidinol dehydrogenase

1986 • 19 citations

Steady-State Kinetics of Cabbage Histidinol Dehydrogenase

1994 • 17 citations

Half-sites oxidation of bovine liver uridine diphosphate glucose dehydrogenase

1978 • 17 citations

Reaction of uridine diphosphate galactose 4-epimerase with a suicide inactivator

1990 • 16 citations

Studies on the mechanism of action of UDP-D-glucose dehydrogenase from beef liver. II

1972 • 13 citations

p-(Bromoacetamido)phenyl uridyl pyrophosphate: an active-site-directed irreversible inhibitor for uridine diphosphate galactose 4-epimerase

1979 • 7 citations

Site-Directed Mutagenesis Shows That the Conserved Cysteine Residues of Histidinol Dehydrogenase Are Not Essential for Catalysis

1993 • 6 citations