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A mechanism for regulation of the adhesion-associated protein tyrosine kinase pp125FAK

Data up to Jan 2025

Published1996
Citations488
References24

Total Citations Per Year

Abstract

References (24)

Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1995 • 4,387 citations

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

1995 • 1,810 citations

pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions.

1992 • 1,456 citations

Protein tyrosine kinase PYK2 involved in Ca2+-induced regulation of ion channel and MAP kinase functions

1995 • 1,367 citations

Autophosphorylation of the Focal Adhesion Kinase, ppl25FAK, Directs SH2-Dependent Binding of pp60src

1994 • 1,168 citations

Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src.

1994 • 844 citations

Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin.

1992 • 811 citations

Inducibility and negative autoregulation of CREM: An alternative promoter directs the expression of ICER, an early response repressor

1993 • 592 citations

pp125FAK-Dependent Tyrosine Phosphorylation of Paxillin Creates a High-Affinity Binding Site for Crk

1995 • 534 citations

Focal adhesion kinase and associated proteins

1994 • 525 citations

Monoclonal antibodies to individual tyrosine-phosphorylated protein substrates of oncogene-encoded tyrosine kinases.

1990 • 480 citations

Identification of sequences required for the efficient localization of the focal adhesion kinase, pp125FAK, to cellular focal adhesions.

1993 • 408 citations

Cloning and Characterization of Cell Adhesion Kinase β, a Novel Protein-tyrosine Kinase of the Focal Adhesion Kinase Subfamily

1995 • 385 citations

Identification and Characterization of a Novel Related Adhesion Focal Tyrosine Kinase (RAFTK) from Megakaryocytes and Brain

1995 • 365 citations

Autonomous Expression of a Noncatalytic Domain of the Focal Adhesion-Associated Protein Tyrosine Kinase pp125FAK

1993 • 282 citations

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1995 • 273 citations

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1993 • 189 citations

A kinase-related protein stabilizes unphosphorylated smooth muscle myosin minifilaments in the presence of ATP

1993 • 120 citations

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1991 • 116 citations

Calspermin Gene Transcription Is Regulated by Two Cyclic AMP Response Elements Contained in an Alternative Promoter in the Calmodulin Kinase IV Gene

1995 • 116 citations

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1993 • 99 citations

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1992 • 48 citations

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1994 • 47 citations

Developmentally regulated expression of two novel platelet-derived growth factor alpha-receptor transcripts in human teratocarcinoma cells.

1994 • 32 citations

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A mechanism for regulation of the adhesion-associated protein tyrosine kinase pp125FAK (1996) – Nature | Metascience Observatory Explorer