The effect of Escherichia coli heat-stable enterotoxin on protein kinase activity

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

The Protein Kinase Family: Conserved Features and Deduced Phylogeny of the Catalytic Domains

1988 • 5,115 citations

Inositol trisphosphate and diacylglycerol as second messengers

1984 • 3,535 citations

Ultrasensitive Stain for Proteins in Polyacrylamide Gels Shows Regional Variation in Cerebrospinal Fluid Proteins

1981 • 2,972 citations

Molecular Weight Determination of Protein-Dodecyl Sulfate Complexes by Gel Electrophoresis in a Discontinuous Buffer System

1971 • 2,019 citations

Fluorometric assay of proteins in the nanogram range

1973 • 1,640 citations

Physiology of the Gastrointestinal Tract.

1982 • 1,635 citations

Intestinal Epithelial Cell Surface Membrane Glycoprotein Synthesis

1973 • 1,111 citations

Test for Escherichia coli Enterotoxin Using Infant Mice: Application in a Study of Diarrhea in Children in Honolulu

1972 • 900 citations

Heat-stable enterotoxin of Escherichia coli: in vitro effects on guanylate cyclase activity, cyclic GMP concentration, and ion transport in small intestine.

1978 • 563 citations

Decrease in cytosolic calcium/phospholipid-dependent protein kinase activity following phorbol ester treatment of EL4 thymoma cells.

1982 • 417 citations

A role of calcium-activated phospholipid-dependent protein kinase in human platelet activation. Comparison of thrombin and collagen actions.

1983 • 368 citations

Role of cyclic GMP in the action of heat-stable enterotoxin of Escherichia coli

1978 • 363 citations

Alfred P. Sloan Jr. prize. Studies and prospectives of the protein kinase C family for cellular regulation

1989 • 298 citations

Activation of Intestinal Guanylate Cyclase by Heat-Stable Enterotoxin of Escherichia coli: Studies of Tissue Specificity, Potential Receptors, and Intermediates

1980 • 216 citations

Protein kinase C catalyzes phosphorylation of guanylate cyclase in vitro.

1985 • 140 citations

Mode of action of heat-stable Escherichia coli enterotoxin Tissue and subcellular specificities and role of cyclic GMP

1980 • 119 citations

Characterization of the receptor for heat-stable enterotoxin from Escherichia coli in rat intestine.

1986 • 101 citations

In Vitro Antisecretory Effects of Trifluoperazine and Other Neuroleptics in Rabbit and Human Small Intestine

1980 • 87 citations

Phorbol ester stimulation of active anion secretion in intestine

1985 • 81 citations

[13] Assay of cyclic nucleotides by radioimmunoassay methods

1974 • 70 citations

Nerve and Muscle: Membranes, Cells, and Systems

1980 • 58 citations

Activation of protein kinase C by a tumor‐promoting phorbol ester in pancreatic islets

1984 • 57 citations

CONTROL OF APICAL SODIUM PERMEABILITY IN THE TOAD URINARY BLADDER BY ALDOSTERONE

1981 • 56 citations

Effect of Escherichia coli Heat-Stable Enterotoxin on Cyclic GMP Levels in Mouse Intestine

1978 • 54 citations

The mechanism of action of Escherichia coli heat-stable toxin

1984 • 48 citations

Characterization of the mechanism of action of Escherichia coli heat-stable enterotoxin

1984 • 47 citations

Guanylate cyclase assay methods.

1979 • 47 citations

Evidence for protein kinase C as a regulator of intestinal electrolyte transport

1985 • 47 citations

The Effect of Calcium and Prostaglandin Inhibitors on the Intestinal Fluid Response to Heat-Stable Enterotoxin of Escherichia coli

1982 • 46 citations

Inhibition of the secretory activity of Escherichia coli heat-stable enterotoxin by indomethacin

1978 • 45 citations

Solubilization and partial characterization of the intestinal receptor for Escherichia coli heat-stable enterotoxin

1984 • 38 citations

Effect of chlorpromazine on the secretory activity of Escherichia coli heat-stable enterotoxin

1979 • 36 citations

Mechanisms by which Cyclic Nucleotides and Other Intracellular Mediators Regulate Secretion

1985 • 34 citations

Lanthanum chloride inhibition of the secretory response to Escherichia coli heat-stable enterotoxin

1982 • 26 citations

Biomembranes and cell function

1983 • 24 citations

Hormonal regulation of epithelial transport of ions and water.

1981 • 20 citations

Effect of chemical and pharmacological agents on the secretory activity induced by Escherichia coli heat-stable enterotoxin

1981 • 17 citations

Microbial Toxins and Diarrhoeal Disease

1985 • 11 citations

Nerve and Muscle. Membranes, Cells and Systems

1981 • 9 citations

A possible role for calcium in cyclic nucleotide mediated fluid secretion

1981 • 4 citations

Effect of lodoxamide on the secretory response induced by Escherichia coli and Vibrio cholerae enterotoxins in infant mice

1984 • 4 citations

METABOLISM AND INTRACELLULAR DISTRIBUTION OF A FLUORESCENT ANALOGUE OF PHOSPHATIDIC ACID IN CULTURED FIBROBLASTS*

1983 • 4 citations