STABILIZATION OF DIHYDROFOLATE REDUCTASE BY INHIBITORS IN VIVO AND IN VITRO*

DISC ELECTROPHORESIS – II METHOD AND APPLICATION TO HUMAN SERUM PROTEINS*

1964 • 18,916 citations

A simple efficient liquid scintillator for counting aqueous solutions in a liquid scintillation counter

1960 • 7,610 citations

Functions of Lysosomes

1966 • 2,942 citations

Protein Purification by Affinity Chromatography

1970 • 2,809 citations

Control of Enzyme Levels in Animal Tissues

1970 • 680 citations

Induction of tyrosine alpha-ketoglutarate transaminase by steroid hormones in a newly established tissue culture cell line.

1966 • 484 citations

Crystalline Dihydropteroylglutamic Acid

1960 • 461 citations

Carrier-mediated Transport of the Folic Acid Analogue, Methotrexate, in the L1210 Leukemia Cell

1968 • 384 citations

Turnover of Rat Liver Tyrosine Transaminase: Stabilization after Inhibition of Protein Synthesis

1967 • 287 citations

Effect of substrate decomposition on the spectrophotometric assay of dihydrofolate reductase

1967 • 235 citations

Treatment of leukemia with large doses of methotrexate and folinic acid: clinical-biochemical correlates

1969 • 234 citations

Growth Regulating Substances for Animal Cells in Culture.

1968 • 210 citations

Studies on the Inhibition of Dihydrofolate Reductase by the Folate Antagonists

1964 • 176 citations

Dihydrofolate Reductase from a Resistant Subline of the L1210 Lymphoma

1967 • 109 citations

Thymidine as a synchronizing agent. I. Nucleic acid and protein formation in synchronous HeLa cultures treated with excess thymidine

1969 • 95 citations

THE “INDUCTION” OF DIHYDROFOLIC REDUCTASE ACTIVITY IN LEUKOCYTES AND ERYTHROCYTES OF PATIENTS TREATED WITH AMETHOPTERIN*

1963 • 92 citations

Increase of dihydrofolate reductase activity in cultured mammalian cells after exposure to methotrexate.

1967 • 74 citations

"Induction" of dihydrofolate reductase: purification and properties of the "induced" human erythrocyte and leukocyte enzyme and normal bone marrow enzyme.

1970 • 43 citations

Multiple forms of dihydrofolate reductase

1968 • 37 citations

Studies on folic reductase. 3. The level of enzyme activity and response to methotrexate of transplantable mouse tumors.

1965 • 32 citations

A colorimetric assay system for tetrahydrofolate dehydrogenase

1968 • 22 citations

Dihydrofolate Reductase from the L1210 R Murine Lymphoma

1967 • 14 citations

Variation of Dihydrofolate Reductase Activity During <italic>In Vitro</italic> and <italic>In Vivo</italic> Growth of Sublines of L1210 Lymphoma<xref ref-type="fn" rid="FN2">2</xref>

1971 • 12 citations