Post-translational regulation of neuronal acetylcholine receptors stably expressed in a mouse fibroblast cell line

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics

1988 • 1,699 citations

Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma cells.

1990 • 1,507 citations

The Diversity of Neuronal Nicotinic Acetylcholine Receptors

1993 • 1,040 citations

A subtype of nicotinic cholinergic receptor in rat brain is composed of alpha 4 and beta 2 subunits and is up-regulated by chronic nicotine treatment.

1992 • 858 citations

Evidence that Tobacco Smoking Increases the Density of (−)‐[³H]Nicotine Binding Sites in Human Brain

1988 • 554 citations

Nicotine binding and nicotinic receptor subunit RNA after chronic nicotine treatment

1992 • 540 citations

Pentameric structure and subunit stoichiometry of a neuronal nicotinic acetylcholine receptor

1991 • 463 citations

Regulation of neurotransmitter receptor desensitization by protein phosphorylation

1990 • 439 citations

Phosphorylation of the nicotinic acetylcholine receptor regulates its rate of desensitization

1986 • 414 citations

Nicotine-induced increase in neuronal nicotinic receptors results from a decrease in the rate of receptor turnover.

1994 • 381 citations

Neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes have a pentameric quaternary structure

1991 • 313 citations

Neurons assemble acetylcholine receptors with as many as three kinds of subunits while maintaining subunit segregation among receptor subtypes

1993 • 303 citations

Purification and characterization of a nicotinic acetylcholine receptor from rat brain.

1987 • 300 citations

Neurons Can Maintain Multiple Classes of Nicotinic Acetylcholine Receptors Distinguished by Different Subunit Compositions

1995 • 293 citations

In Vivo Regulation of [³H]Acetylcholine Recognition Sites in Brain by Nicotinic Cholinergic Drugs

1985 • 283 citations

Smooth muscle myosin phosphatase inhibition and force enhancement by black sponge toxin

1987 • 280 citations

Characterization of bovine and human neuronal nicotinic acetylcholine receptors using monoclonal antibodies

1988 • 241 citations

The α5 gene product assembles with multiple acetylcholine receptor subunits to form distinctive receptor subtypes in brain

1992 • 205 citations

Structural and pharmacological characterization of the major brain nicotinic acetylcholine receptor subtype stably expressed in mouse fibroblasts.

1991 • 196 citations

Structurally different neuronal nicotinic acetylcholine receptor subtypes purified and characterized using monoclonal antibodies

1987 • 137 citations

cDNA clones coding for the structural subunit of a chicken brain nicotinic acetylcholine receptor

1988 • 131 citations

Cyclic AMP regulates the proportion of functional acetylcholine receptors on chicken ciliary ganglion neurons.

1987 • 131 citations

Evidence for the regulation of exocytic transport by protein phosphorylation.

1992 • 126 citations

Coexpression of multiple acetylcholine receptor genes in neurons: quantification of transcripts during development.

1993 • 124 citations

Activators of protein kinase C enhance acetylcholine receptor desensitization in sympathetic ganglion neurons.

1987 • 116 citations

Coexpression of multiple acetylcholine receptor genes in neurons: quantification of transcripts during development

1993 • 113 citations

Okadaic acid induces golgi apparatus fragmentation and arrest of intracellular transport

1991 • 113 citations

Expression of nicotinic acetylcholine receptor subtypes in brain and retina

1991 • 110 citations

Expression and regulation of neuronal acetylcholine receptor mRNA in chick ciliary ganglia

1988 • 101 citations

The tumour promoter okadaic acid inhibits reticulocyte-lysate protein synthesis by increasing the net phosphorylation of elongation factor 2

1989 • 94 citations

Characterization of a component in chick ciliary ganglia that cross- reacts with monoclonal antibodies to muscle and electric organ acetylcholine receptor

1985 • 88 citations

Changes in the number, function, and regulation of nicotinic acetylcholine receptors during neuronal development

1989 • 87 citations

Innervation and target tissue interactions differentially regulate acetylcholine receptor subunit mRNA levels in developing neurons in situ

1995 • 84 citations

Expression of neuronal acetylcholine receptor genes in vertebrate skeletal muscle during development

1995 • 84 citations

Neuronal acetylcholine receptors: fate of surface and internal pools in cell culture

1987 • 79 citations

Acetylcholine receptor assembly is stimulated by phosphorylation of its γ subunit

1991 • 75 citations

Efficiency of acetylcholine receptor subunit assembly and its regulation by cAMP.

1991 • 74 citations

Transcriptional and post-transcriptional regulation of c-fos expression by the tumor promoter okadaic acid.

1991 • 65 citations

Cyclic AMP-dependent phosphorylation of a neuronal acetylcholine receptor alpha-type subunit

1990 • 59 citations

Compartmentalized transcription of acetylcholine receptor genes during motor endplate epigenesis.

1991 • 55 citations

cAMP stimulation of acetylcholine receptor expression is mediated through posttranslational mechanisms.

1991 • 46 citations