Protein engineering by cDNA recombination in yeasts: shuffling of mammalian cytochrome P-450 functions

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

The double-strand-break repair model for recombination

1983 • 2,468 citations

The Liver: Biology and Pathobiology.

1983 • 1,628 citations

P450 GENES: STRUCTURE, EVOLUTION, AND REGULATION

1987 • 1,559 citations

Yeast transformation: a model system for the study of recombination.

1981 • 1,491 citations

High-resolution crystal structure of cytochrome P450cam

1987 • 1,396 citations

The P450 Gene Superfamily: Recommended Nomenclature

1987 • 812 citations

A GAL10-CYC1 hybrid yeast promoter identifies the GAL4 regulatory region as an upstream site.

1982 • 575 citations

Plasmid construction by homologous recombination in yeast

1987 • 560 citations

Yeast recombination: the association between double-strand gap repair and crossing-over.

1983 • 432 citations

On the membrane topology of vertebrate cytochrome P-450 proteins.

1988 • 362 citations

The Liver: Biology and Pathology

1989 • 348 citations

Efficient synthesis of enzymatically active calf chymosin in Saccharomyces cerevisiae

1983 • 337 citations

Genes for Cytochrome P-450 and Their Regulatio

1986 • 227 citations

The murine Ah locus. Comparison of the complete cytochrome P1-450 and P3-450 cDNA nucleotide and amino acid sequences.

1984 • 199 citations

Determination of the membrane topology of the phenobarbital-inducible rat liver cytochrome P-450 isoenzyme PB-4 using site-specific antibodies.

1987 • 160 citations

Synthesis of functional mouse cytochromes P-450 P1 and chimeric P-450 P3-1 in the yeast Saccharomyces cerevisiae

1988 • 132 citations

cDNA cloning and functional expression in yeast Saccharomyces cerevisiae of β‐naphthoflavone‐induced rabbit liver P‐450 LM4 and LM6

1988 • 101 citations

Fungal recombination.

1985 • 98 citations

Induction of drug-metabolizing enzymes: Mechanisms and consequences

1986 • 95 citations

Secondary structure determination for α‐neurotoxin from Dendroaspis polylepis polylepis based on sequence‐specific ¹H‐nuclear‐magnetic‐resonance assignments

1988 • 86 citations

Expression of P1-450 and P3-450 DNA coding sequences as enzymatically active cytochromes P-450 in mammalian cells.

1987 • 62 citations

Formation of genes coding for hybrid proteins by recombination between related, cloned genes inE. coli

1983 • 59 citations

Expression inSaccharomyces cerevisiaeof Chimeric Cytochrome P450 cDNAs Constructed from cDNAs for Rat Cytochrome P450c and P450d

1987 • 58 citations

Gene Conversion Adjacent to Regions of Double-Strand Break Repair

1988 • 53 citations

Gene conversion adjacent to regions of double-strand break repair.

1988 • 38 citations

Intramolecular recombination between partially homologous sequences in Escherichia coli and Xenopus laevis oocytes.

1987 • 23 citations