Antagonism of adenosine A2A receptors underlies the behavioural activating effect of caffeine and is associated with reduced expression of messenger RNA for NGFI-A and NGFI-B in caudate–putamen and nucleus accumbens

D ₁ and D ₂ Dopamine Receptor-regulated Gene Expression of Striatonigral and Striatopallidal Neurons

1990 • 2,873 citations

The regulation and function of c-fos and other immediate early genes in the nervous system

1990 • 2,392 citations

The rat brain in stereotaxic coordinates (2nd edn)

1987 • 1,743 citations

Nomenclature and classification of purinoceptors.

1994 • 1,569 citations

A Nerve Growth Factor-Induced Gene Encodes a Possible Transcriptional Regulatory Factor

1987 • 1,217 citations

Effects of nicotine on the nucleus accumbens and similarity to those of addictive drugs

1996 • 1,083 citations

Intravenous cocaine, morphine, and amphetamine preferentially increase extracellular dopamine in the "shell" as compared with the "core" of the rat nucleus accumbens.

1995 • 857 citations

Adenosine receptors and behavioral actions of methylxanthines.

1981 • 705 citations

Differential expression of immediate early genes in the hippocampus and spinal cord

1990 • 670 citations

Nerve growth factor induces a gene homologous to the glucocorticoid receptor gene

1988 • 661 citations

How does adenosine inhibit transmitter release?

1988 • 649 citations

Molecular cloning of the rat A2 adenosine receptor: selective co-expression with D2 dopamine receptors in rat striatum

1992 • 646 citations

Adenosine, Adenosine Receptors and the Actions of Caffeine *

1995 • 563 citations

Tissue distribution of adenosine receptor mRNAs in the rat

1996 • 560 citations

Striatal Restricted Adenosine A₂ Receptor (RDC8) Is Expressed by Enkephalin but Not by Substance P Neurons: An In Situ Hybridization Histochemistry Study

1991 • 527 citations

Opposite Modulation of Cocaine-Seeking Behavior by D ₁ - and D ₂ -Like Dopamine Receptor Agonists

1996 • 493 citations

Dopamine receptor gene expression by enkephalin neurons in rat forebrain.

1990 • 469 citations

Are methylxanthine effects due to antagonism of endogenous adenosine?

1979 • 419 citations

Autoradiographic localization of adenosine receptors in rat brain using [3H]cyclohexyladenosine

1982 • 417 citations

Binding of the A1-selective adenosine antagonist 8-cyclopentyl-1,3-dipropylxanthine to rat brain membranes

1987 • 376 citations

Adenosine-dopamine interactions in the brain

1992 • 366 citations

Molecular Cloning and Characterization of a Rat A₁-Adenosine Receptor that is Widely Expressed in Brain and Spinal Cord

1991 • 341 citations

Adenosine Inhibition of Mesopontine Cholinergic Neurons: Implications for EEG Arousal

1994 • 338 citations

The distribution of adenosine a1 receptors and 5'-nucleotidase in the brain of some commonly used experimental animals

1987 • 322 citations

Proto-oncogene transcription factors and epilepsy

1991 • 252 citations

Adenosine A2 receptors regulate the gene expression of striatopallidal and striatonigral neurons

1993 • 248 citations

Cloning and expression of an A1 adenosine receptor from rat brain.

1991 • 235 citations

Evidence for functionally important adenosine A2a receptors in the rat hippocampus

1994 • 219 citations

Dynamic regulation of NGFI-A (zif268, egr1) gene expression in the striatum

1992 • 213 citations

Adenosine A2 receptors: Selective localization in the human basal ganglia and alterations with disease

1991 • 198 citations

The non-xanthine heterocyclic compound SCH 58261 is a new potent and selective A2a adenosine receptor antagonist.

1996 • 197 citations

Evidence for high-affinity binding sites for the adenosine A2A receptor agonist [3H] CGS 21680 in the rat hippocampus and cerebral cortex that are different from striatal A2A receptors

1996 • 183 citations

8‐(3‐Chlorostyryl)caffeine (CSC) is a selective A₂‐adenosine antagonist in vitro and in vivo

1993 • 174 citations

Promotion of sleep mediated by the A2a-adenosine receptor and possible involvement of this receptor in the sleep induced by prostaglandin D2 in rats.

1996 • 162 citations

Autoradiographic evidence for G-protein coupled A2-receptors in rat neostriatum using [3H]-CGS 21680 as a ligand

1990 • 154 citations

Blockade of A_2a Adenosine Receptors Positively Modulates Turning Behaviour and c‐Fos Expression Induced by D₁ Agonists in Dopamine‐denervated Rats

1996 • 145 citations

Effect of long term caffeine treatment on A1 and A2 adenosine receptor binding and on mRNA levels in rat brain

1993 • 143 citations

Differences in the regional and cellular localization of c-fos messenger RNA induced by amphetamine, cocaine and caffeine in the rat

1994 • 142 citations

Biphasic changes in locomotor behavior and in expression of mRNA for NGFI-A and NGFI-B in rat striatum following acute caffeine administration

1995 • 129 citations

The cellular localization of adenosine receptors in rat neostriatum

1989 • 123 citations

Photocell measurements of rat motor activity

1991 • 113 citations

On the mechanism by which methylxanthines enhance apomorphine-induced rotation behaviour in the rat

1983 • 106 citations

Behavioral effects of vehicles: DMSO, ethanol, Tween-20, Tween-80, and emulphor-620

1995 • 105 citations

Adenosine A2a receptor mRNA is expressed by enkephalin cells but not by somatostatin cells in rat striatum: a co-expression study

1994 • 105 citations

Adenosine receptor antagonists potentiate dopamine receptor agonist-induced rotational behavior in 6-hydroxydopamine-lesioned rats

1993 • 97 citations

Reinstatement of extinguished cocaine-taking behavior by cocaine and caffeine

1994 • 87 citations

Adenosinergic modulation of caffeine-induced c-fos mRNA expression in mouse brain

1989 • 70 citations

Comparison of the behavioural effects of an adenosine A1/A2-receptor antagonist, CGS 15943A, and an A1-selective antagonist, DPCPX

1991 • 70 citations

Striatal adenosine levels measured ‘in vivo’ by microdialysis in rats with unilateral dopamine denervation

1987 • 67 citations

Increased expression of c-jun, junB, AP-1, and preproenkephalin mRNA in rat striatum following a single injection of caffeine

1995 • 50 citations

Does adenosine receptor blockade mediate caffeine-induced rotational behavior?

1995 • 45 citations

Role of adenosine A2a receptors in the nucleus accumbens

1994 • 41 citations

Effects of selective agonists and antagonists for A1 or A2A adenosine receptors on sleep-waking patterns in rats

1996 • 33 citations

CGS 15943, a nonxanthine adenosine receptor antagonist: Effects on locomotor activity of nontolerant and caffeine-tolerant rats

1991 • 30 citations

Caffeine-induced expression of c-fos mRNA and NGFI-A mRNA in caudate putamen and in nucleus accumbens are differentially affected by the N-methyl-d-aspartate receptor antagonist MK-801

1996 • 27 citations

Stimulation of adenosine A1 receptors prevents the EEG arousal due to dopamine D1 receptor activation in rabbits

1996 • 21 citations

Caffeine‐induced expression of the proto‐oncogene c‐fos in rat striatum is increased aftei dopamine denervation

1993 • 8 citations