Minireview: Culture of Airway Epithelial Cells: Research Techniques

Birth Defects: Original Article Series.

1971 • 1,225 citations

D-valine as a selective agent for normal human and rodent epithelial cells in culture

1975 • 392 citations

Bombesin and the C-terminal tetradecapeptide of gastrin-releasing peptide are growth factors for normal human bronchial epithelial cells

1984 • 354 citations

Ciliary activity of cultured rabbit tracheal epithelium: beat pattern and metachrony

1981 • 331 citations

Clonal growth of normal adult human bronchial epithelial cells in a serum-free medium

1982 • 278 citations

Cystic fibrosis decreases the apical membrane chloride permeability of monolayers cultured from cells of tracheal epithelium.

1985 • 201 citations

Clonal growth of epithelial cells from normal adult human bronchus.

1981 • 198 citations

Transformation of Human Bronchial Epithelial Cells Transfected by Harvey ras Oncogene

1985 • 198 citations

Light and Electron Microscopic Studies

1977 • 193 citations

Continuous multiplication of rabbit tracheal epithelial cells in a defined, hormone-supplemented medium

1982 • 183 citations

Growth and differentiation of human nasal epithelial cells in culture. Serum-free, hormone-supplemented medium and proteoglycan synthesis.

1985 • 169 citations

Detection, isolation, and analysis of a released Bordetella pertussis product toxic to cultured tracheal cells

1982 • 155 citations

Electrical properties of dog tracheal epithelial cells grown in monolayer culture

1984 • 150 citations

Repopulation of denuded tracheal grafts with normal, preneoplastic, and neoplastic epithelial cell populations.

1978 • 128 citations

Culture of human nasal epithelial cells on collagen matrix supports. A comparison of bioelectric properties of normal and cystic fibrosis epithelia.

1985 • 109 citations

Growth and Differentiation of Hamster Tracheal Epithelial Cells in Culture

1984 • 106 citations

Induction of squamous differentiation of normal human bronchial epithelial cells by small amounts of serum

1984 • 101 citations

Biochemical characterization of mucous glycoproteins synthesized and secreted by hamster tracheal epithelial cells in primary culture.

1985 • 94 citations

Isolation and identification of clara cells from rabbit lung

1980 • 89 citations

Asbestos-Induced Epithelial Changes in Organ Cultures of Hamster Trachea: Inhibition by Retinyl Methyl Ether

1980 • 86 citations

An acellular human amnionic membrane model for in vitro culture of type ii pneumocytes: The role of the basement membrane in cell morphology and function

1984 • 85 citations

Hydration Kinetics of Exocytosed Mucins in Cultured Secretory Cells of the Rabbit Trachea: A New Model

1984 • 84 citations

Electrical properties of monolayers cultured from cells of human tracheal mucosa

1985 • 73 citations

Morphological and Cytochemical Effects of Marijuana Cigarette Smoke on Epithelioid Cells of Lung Explants from Mice

1971 • 68 citations

PERSISTENCE OF ABNORMAL CHLORIDE ION PERMEABILITY IN CYSTIC FIBROSIS NASAL EPITHELIAL CELLS IN HETEROLOGOUS CULTURE

1985 • 65 citations

Binding of (3H)benzo(a)pyrene to DNA in cultured human bronchus.

1976 • 64 citations

Ion transport by primary cultures of canine tracheal epithelium: Methodology, morphology, and electrophysiology

1985 • 61 citations

Quantitation of cell proliferation, colony formation, and carcinogen induced cytotoxicity of rat tracheal epithelial cells grown in culture on 3T3 feeder layers

1983 • 53 citations

Chapter 2 Identification and Culture of Human Bronchial Epithelial Cells

1980 • 51 citations

Differentiated function in cultured epithelia derived from thick ascending limbs

1982 • 50 citations

Glycoprotein Secretion by Tracheal Explants Cultured from Rats Exposed to Ozone^1–2

1977 • 50 citations

Acute effects of 12-Otetradecanoylphorbol-13-acetate, teleocidin B, or 2,3,7,8-tetrachlorodibenzo-p-dioxin on cultured normal human bronchial epithelial cells

1984 • 50 citations

Chloride uptake into cultured airway epithelial cells from cystic fibrosis patients and normal individuals.

1985 • 48 citations

Differences in the attachment of Mycoplasma pneumoniae cells and membranes to tracheal epithelium

1977 • 47 citations

Relationship of ornithine decarboxylase activity and cAMP metabolism to proliferation of normal human bronchial epithelial cells

1985 • 42 citations

Secretory activity of the human bronchial mucous glands in vitro

1972 • 42 citations

High frequency of carcinogen-induced early, preneoplastic changes in rat tracheal epithelial cells in culture.

1983 • 40 citations

Biological actions of nitroarenes in short-term tests on Salmonella, cultured mammalian cells and cultured human tracheal tissues: possible basis for regulatory control.

1983 • 40 citations

Long-Term Maintenance of Differentiated Respiratory Epithelium in Organ Culture I. Medium Composition

1975 • 39 citations

Comparison of the noise of different electron detection systems using a scintillator‐photomultiplier combination

1981 • 38 citations

The Effect of Vitamin A on Cellular Differentiation and Mucous Glycoprotein Synthesis in Long-Term Rat Tracheal Organ Cultures

1979 • 36 citations

Establishment of epithelial cell lines following exposure of cultured tracheal epithelium to 12-O-tetradecanoyl-phorbol-13-acetate.

1978 • 36 citations

Morphological changes in rat tracheal cells during the adaptive and early growth phase in primary cell culture

1985 • 36 citations

Neoplastic transformation of primary tracheal epithelial cell cultures

1983 • 35 citations

Cell attachment, growth characteristics and surface morphology of human upper‐respiratory tract epithelium cultured on extracellular matrix

1983 • 34 citations

Putrescine stimulates growth of human bronchial epithelial cells in primary culture

1980 • 33 citations

Respiratory tract epithelium in primary culture: concurrent growth and differentiation during establishment

1978 • 33 citations

Intracellular levels of adenosine triphosphate in hamster trachea organ cultures exposed toMycoplasma pneumoniae cells or membranes

1977 • 32 citations

Oxygen toxicity in fetal organ culture. II. The developing lung.

1974 • 31 citations

Growth inhibition and transformation of a human fetal tracheal epithelial cell line by long-term exposure to diethylnitrosamine

1985 • 31 citations

Morphology and quantitation of ciliated outgrowths from cultured rabbit tracheal explants.

1983 • 30 citations

Human respiratory tract secretions. 1. Mucous glycoproteins secreted by cultured nasal polyp epithelium from subjects with allergic rhinitis and with cystic fibrosis.

1974 • 30 citations

Regulation of Differentiation of Tracheal Epithelial Cells by Retinoids

1985 • 29 citations

Attachment of Mycoplasma pneumoniae to hamster tracheal organ cultures, tracheal outgrowth monolayers, human erythrocytes, and WiDr human tissue culture cells

1982 • 28 citations

Cellular Basis for Susceptibility to Mouse Cytomegalovirus: Evidence from Tracheal Organ Culture

1979 • 28 citations

Ciliated respiratory epithelial monolayers: new model for Mycoplasma pneumoniae infection

1978 • 27 citations

Differentiation of Normal and Cultured Preneoplastic Tracheal Epithelial Cells in Rats: Importance of Epithelial Mesenchymal Interactions<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1980 • 27 citations

Relationship of epithelial growth to mitotic rate in mouse embryonic lung developing in vitro

1968 • 26 citations

Submersion culture of the intact fetal lung

1983 • 25 citations

Pyruvate regulation of growth and differentiation in primary cultures of rat tracheal epithelial cells

1984 • 24 citations

Glycoprotein secretion by cultured hamster trachea epithelial cells: A model system for in vitro studies of mucus synthesis

1980 • 24 citations

Enhancement of Carcinogenesis in Cultured Respiratory Tract Epithelium by 12‐O‐Tetradecanoylphorbol‐13‐Acetate

1980 • 24 citations

Cilia Formation in Cultures of Human Lung Cancer Cells Treated With Dimethyl Sulfoxide

1976 • 23 citations

Synthesis of mucin glycoproteins by epithelial cells isolated from swine trachea by specific proteolysis

1984 • 22 citations

Prevention and reversal by a retinoid of 3,4-benzpyrene- and cigarette smoke condensate-induced hyperplasia and metaplasia of rodent respiratory epithelia in organ culture.

1982 • 22 citations

Effects of retinoic acid on cell proliferation and cell differentiation in a rat tracheal epithelial cell line

1982 • 21 citations

Metabolism, DNA binding, and cytotoxicity of aflatoxin B1 in tracheal explants from Syrian hamster

1984 • 21 citations

A comparison between the activation of benzo[a]pyrene in organ cultures and microsomes from the tracheal epithelium of rats and hamsters

1983 • 21 citations

Chapter 1 Methods of Organ Culture for Human Bronchus

1980 • 21 citations

Reestablishment of a mucociliary epithelium in tracheal organ cultures exposed to retinyl acetate: a biochemical and morphometric study.

1980 • 20 citations

[3H]Benzo(a)pyrene metabolism in tracheal epithelial microsomes and tracheal organ cultures.

1978 • 19 citations

Effect of squamous metaplasia on infection of hamster trachea organ cultures with Mycoplasma pneumoniae

1977 • 19 citations

Incorporation of labeled glucosamine into glycoproteins by organ cultures of hamster trachea: Adverse effects of hepes buffer

1975 • 19 citations

Chapter 4 Explant Culture of Human Peripheral Lung

1980 • 19 citations

Preparation and long-term cultivation of porcine tracheal and lung organ cultures by alternate exposure to gaseous and liquid medium phases

1978 • 18 citations

Mucus secretion by the epithelium of the bronchioles of cigarette smokers

1981 • 18 citations

Increased DNA content as an early marker of transformation in carcinogen-exposed rat tracheal cell cultures

1983 • 18 citations

Scanning electron microscopical investigations on the respiratory epithelium of the Syrian golden hamster. I. Postnatal differentiation.

1980 • 17 citations

Cytopathogenicity of Mycoplasma hyopneumoniae in porcine tracheal ring and lung explant organ cultures alone and in combination with monolayer cultures of fetal lung fibroblasts

1978 • 17 citations

Comparative Sensitivities of Oviduct and Tracheal Organ Cultures and Chicken Embryo Kidney Cell Cultures to Infectious Bronchitis Virus

1983 • 17 citations

Preparation of large numbers of uniform tracheal organ cultures for long term studies

1976 • 17 citations

Studies of oxygen toxicity in cultured human neonatal respiratory epithelium

1979 • 16 citations

Exfoliation of respiratory epithelium in hamster tracheal organ cultures infected with Mycoplasma pneumoniae

1980 • 16 citations

The effect of 12-O-tetradecanoylphorbol-13-acetate and other tumor promoters on the colony formation of rat tracheal epithelial cells in culture

1984 • 15 citations

Murine Cytomegalovirus Infection of Epithelial Cells in Mouse Tracheal Ring Organ Culture

1977 • 15 citations

Growth Requirements of Ferret Tracheal Epithelial Cells in Primary Culture

1985 • 15 citations

Selection of carcinogen-altered rat tracheal epithelial cells preexposed to 7,12-dimethylbenz[a]anthracene by their loss of a need for pyruvate to survive in culture

1984 • 14 citations

Electron microscopy of equine respiratory viruses in organ cultures of equine fetal respiratory tract epithelium.

1984 • 14 citations

Enhanced induction of the anchorage-independent phenotype in initiated rat tracheal epithelial cell cultures by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate.

1984 • 13 citations

Studies with some influenza B viruses in cell cultures, hamsters and hamster tracheal organ cultures

1981 • 12 citations

Identification of early carcinogen-induced changes in nutritional and substrate requirements in cultured tracheal epithelial cells

1982 • 12 citations

Changes in stem cell populations of rat tracheal epithelial cell cultures at an early stage in neoplastic progression.

1985 • 12 citations

Interaction of asbestos with metaplastic squamous epithelium developing in organ cultures of hamster trachea.

1983 • 11 citations

Carcinogen-Induced Changes in Tracheal Epithelium Cultured in Serum-Free, Chemically Defined Medium 2

1976 • 11 citations

Use of tracheal organ cultures in toxicity testing.

1976 • 10 citations

Long-Term Mouse Cytomegalovirus Infection of Tracheal Organ Culture: Relation to Host Cell Replication

1982 • 10 citations

Detection of chemical carcinogens by assay of unscheduled DNA synthesis in rat tracheal epithelium in short-term organ culture

1981 • 10 citations

In vitro behavior of human fetal lung maintained in organ culture

1976 • 10 citations

Isolation of basal and mucous cell populations from rabbit trachea.

1981 • 10 citations

Maintenance of normal, metaplastic, and dysplastic states of adult human bronchial mucosa in organ culture.

1973 • 10 citations

Effect of Environmental Co₂, O₂ and Ph on the Growth of Respiratory Epithelium in Vitro

1979 • 10 citations

Growth of Bacteroides fragilis Inoculated on Rabbit Tracheal Explant in an Atmospheric Environment

1980 • 9 citations

A continuous-flow method of organ culture

1978 • 8 citations

The use of organ cultures in studies of respiratory tract mucin synthesis and secretion

1972 • 8 citations

Influence of substrate on adult tracheal epithelium in culture

1969 • 7 citations

Organ culture of adult Rat and mouse tracheal epithelium: I. Ultrastructure following various culture periods

1976 • 7 citations

Cell Interactions Between Epithelial and Mesenchymal Components in Primary Sheets of Fetal Rat Lung Cells, and the Effects of 3-Methylcholanthrene Treatment 2

1976 • 6 citations

Behavior of Explants from Human Adult Bronchial Epithelium in vitro.

1958 • 6 citations

A culture method giving substantial yields of normal nasopharyngeal epithelial cells for work with Epstein-Barr virus

1983 • 6 citations

Effect of lymphocytes and broncho-alveolar washing cells on the replication of bovine herpesvirus type 1 in tracheal organ cultures

1982 • 6 citations

Effects of Cigarette Smoke Residue on Rabbit Tracheal Epithelium in Organ Culture

1979 • 6 citations

The assessment of tobacco smoke toxicity in organ culture. II. Ultrastructural studies on the immediate response of foetal rabbit tracheal epithelium to short-term exposures of whole smoke

1975 • 6 citations

Effects of reduced calcium on proliferation and cell viability in tumorigenic and nontumorigenic rat tracheal epithelial cell lines

1984 • 5 citations

Surface-glycoprotein patterns of established human lung cancer cell lines and primary cultures.

1985 • 5 citations

Monoclonal murine antibodies with specificity for tissue culture lines of human squamous-cell carcinoma of the lung.

1983 • 5 citations

Virus Isolation from Tracheal Explant Cultures and Oropharyngeal Swabs in Attempts to Detect Persistent Newcastle Disease Virus Infections in Chickens

1985 • 4 citations

In vivo and in vitro growth of a rat tracheal squamous cell carcinoma.

1981 • 4 citations

Mucus and surfactant synthesis and secretion by cultured hamster respiratory cells.

1980 • 4 citations

In vitro culture of human bronchial epithelium.

1975 • 4 citations

Autoradiographic study of DNA repair in respiratory epithelium in short-term organ culture.

1982 • 3 citations

Isolation, culture, and preliminary characterization of mucin‐producing cells from trachea of the domestic fowl

1982 • 2 citations

Heterogeneity in responses of human and rodent respiratory epithelial cells to tumor promoters in culture.

1985 • 2 citations

Growth and characterization of functional epithelial cells on selective substrates.

1980 • 2 citations

Effect of urethane on Swiss mice lung tissue in organ culture and proliferation of epithelial cells 'in vitro'.

1977 • 1 citations

Effect of temperature on commencement of migration of adult tracheal epithelial cells in culture

1969 • 1 citations

Rat tracheal organ culture supports replication of parainfluenza 1 (6/94) virus and promotes 6/94 virus rescue from latently infected human brain cells

1978 • 1 citations

Deleted Work

1955 • 0 citations