X-ray structure of human relaxin at 1.5 A. Comparison to insulin and implications for receptor binding determinants.

The protein data bank: A computer-based archival file for macromolecular structures

1977 • 8,627 citations

Crystallographic R Factor Refinement by Molecular Dynamics

1987 • 1,982 citations

Evaluation of single-crystal X-ray diffraction data from a position-sensitive detector

1988 • 1,516 citations

Resolution of phase ambiguity in macromolecular crystallography

1985 • 1,040 citations

Stereochemically restrained refinement of macromolecular structures

1985 • 614 citations

Monomeric insulins obtained by protein engineering and their medical implications

1988 • 493 citations

Structure of Ribonuclease H Phased at 2 Å Resolution by MAD Analysis of the Selenomethionyl Protein

1990 • 475 citations

Crystal orientation and X-ray pattern prediction routines for area-detector diffractometer systems in macromolecular crystallography

1987 • 396 citations

Receptor-binding region of insulin

1976 • 389 citations

Relaxin modulates synthesis and secretion of procollagenase and collagen by human dermal fibroblasts.

1990 • 320 citations

Extension of molecular replacement: a new search strategy based on Patterson correlation refinement

1990 • 315 citations

Structure of insulin in 4-zinc insulin

1976 • 250 citations

Structure of a genomic clone encoding biologically active human relaxin

1983 • 227 citations

Relaxin gene expression in human ovaries and the predicted structure of a human preprorelaxin by analysis of cDNA clones.

1984 • 198 citations

Cyclic AMP response to recombinant human relaxin by cultured human endometrial cells—A specific and high throughput in vitro bioassay

1990 • 94 citations

The Conformation, Flexibility, and Dynamics of Polypeptide Hormones

1982 • 90 citations

Relaxin in the Male1

1989 • 74 citations

Preparation of biologically active 32P-labeled human relaxin. Displaceable binding to rat uterus, cervix, and brain.

1990 • 70 citations

Relaxin and its structural relationship to insulin

1978 • 68 citations

Structural characterization by mass spectrometry of native and recombinant human relaxin

1990 • 67 citations

Prothoracicotropic hormone has an insulin-like tertiary structure

1987 • 65 citations

On the receptor binding site of relaxins

1988 • 56 citations

Relaxin extracted from protozoa (Tetrahymena pyriformis). Molecular and immunologic properties.

1983 • 54 citations

Isolation, Purification, and the sequence of relaxin from spiny dogfish (Squalus acanthias)

1986 • 46 citations

Cetacean Relaxin

1989 • 42 citations

On the primary and tertiary structure of relaxin from the sand tiger shark (Odontaspis taurus)

1981 • 42 citations

Use of site-directed mutagenesis to obtain isomorphous heavy-atom derivatives for protein crystallography: cysteine-containing mutants of phage T4 lysozyme

1987 • 36 citations

Characterization of chemically synthesized human relaxin by high-performance liquid chromatography

1990 • 32 citations

ON THE THREE‐DIMENSIONAL STRUCTURE OF RELAXIN

1982 • 23 citations