UvrABC nuclease complex repairs thymine glycol, an oxidative DNA base damage

Experiments in molecular genetics

1972 • 28,260 citations

Studies on transformation of Escherichia coli with plasmids

1983 • 11,179 citations

Normal oxidative damage to mitochondrial and nuclear DNA is extensive.

1988 • 1,709 citations

Rate of depurination of native deoxyribonucleic acid

1972 • 1,488 citations

Methods in Virology

1984 • 987 citations

DNA REPAIR ENZYMES

1988 • 822 citations

Chemical Changes Induced in DNA by Ionizing Radiation

1985 • 570 citations

Radiation-induced DNA Damage and Its Repair

1987 • 405 citations

Thymine glycol and thymidine glycol in human and rat urine: a possible assay for oxidative DNA damage.

1984 • 365 citations

DNA N-glycosylases and UV repair

1980 • 307 citations

Energetic coupling between DNA bending and base pair opening.

1988 • 303 citations

Thymine glycols and urea residues in M13 DNA constitute replicative blocksin vitro

1985 • 258 citations

Ap endonucleases and dna glycosylases that recognize oxidative dna damage

1988 • 254 citations

DNA glycosylase activities for thymine residues damaged by ring saturation, fragmentation, or ring contraction are functions of endonuclease III in Escherichia coli.

1984 • 249 citations

Purification and characterization of Escherichia coli endonuclease III from the cloned nth gene

1989 • 212 citations

Anticarcinogenesis and Radiation Protection

1987 • 210 citations

Characterization of the Escherichia coli x-ray endonuclease, endonuclease III

1983 • 202 citations

Endonuclease III (nth) mutants of Escherichia coli.

1985 • 196 citations

A new mechanism for repairing oxidative damage to DNA: (A)BC excinuclease removes AP sites and thymine glycols from DNA

1989 • 177 citations

Mechanism of action of Escherichia coli endonuclease III

1987 • 162 citations

Mechanisms and consequences of DNA damage processing

1987 • 152 citations

A buoyant method for the determination of the superhelix density of closed circular DNA

1971 • 144 citations

The uvrB gene of Escherichia coli has both lexA-repressed and lexA-independent promoters

1982 • 140 citations

Thymlne glycol lesions terminate chain elongation by DNA polymerase I in vitro

1986 • 133 citations

Amplification and purification of UvrA, UvrB, and UvrC proteins of Escherichia coli.

1985 • 124 citations

A new approach to the study of the base-excision repair pathway using methoxyamine.

1985 • 122 citations

The Radiolysis of Pyrimidines in Aqueous Solutions: An Updating Review

1985 • 114 citations

Oxidative damage in DNA

1988 • 108 citations

Possible role for thymine glycol in the selective inhibition of DNA synthesis on oxidized DNA templates.

1985 • 106 citations

Sequence dependence for bypass of thymine glycols in DNA by DNA polymerase I

1986 • 101 citations

Functional effects of cis-thymine glycol lesions on DNA synthesis in vitro

1987 • 101 citations

Exonuclease III recognizes urea residues in oxidized DNA.

1985 • 99 citations

Phosphodiesterases Involved in DNA Repair

1987 • 95 citations

Repair of O6-Methylguanine by ABC Excinuclease of Escherichia coli in vitro

1989 • 94 citations

Excision repair of thymine glycols, urea residues, and apurinic sites in Escherichia coli

1988 • 77 citations

Identification, physical map location and sequence of theden Vgene from bacteriophage T4

1984 • 73 citations

Repair of N-methyl-N'-nitro-N-nitrosoguanidine-induced DNA damage by ABC excinuclease

1987 • 72 citations

LexA protein inhibits transcription of the E. coli uvrA gene in vitro

1982 • 67 citations

NMR studies of abasic sites in DNA duplexes: deoxyadenosine stacks into the helix opposite acyclic lesions

1989 • 59 citations

Mechanism of action of Escherichia coli exonuclease III

1989 • 52 citations

A procedure for the quantitation of relaxed closed circular DNA in the presence of superhelical DNA: An improved fluorometric assay for nicking-closing enzyme

1979 • 51 citations

Properties of antibodies to thymine glycol, a product of the radiolysis of DNA.

1984 • 44 citations

Mechanism of action of Micrococcus luteus .gamma.-endonuclease

1987 • 43 citations

Synthesis of dihydrothymidine and thymidine glycol 5'-triphosphates and their ability to serve as substrates for Escherichia coli DNA polymerase I

1987 • 42 citations

Stereochemistry of the catalytic and light-induced reduction of thymidine to dihydrothymidine and ureido alcohols

1968 • 39 citations

Biological Effect of Thymine Ring Saturation in Coliphage φX174-DNA

1977 • 39 citations

Role of exonuclease III and endonuclease IV in repair of pyrimidine dimers initiated by bacteriophage T4 pyrimidine dimer-DNA glycosylase

1989 • 38 citations

Recognition of the DNA helix stabilizing anthramycin-N2 guanine adduct by UVRABC nuclease

1988 • 36 citations

Recognition and repair of 2-aminofluorene- and 2-(acetylamino)fluorene-DNA adducts by UVRABC nuclease

1989 • 30 citations

Host- and Phage-Mediated Repair of Radiation Damage in Bacteriophage T4

1972 • 28 citations

The DNA bending by acetylaminofluorene residues and by apurinic sites

1989 • 27 citations

Preparation of a short synthetic apurinic oligonucleotide

1986 • 26 citations

Properties of Antibodies to Thymine Glycol, a Product of the Radiolysis of DNA

1984 • 26 citations

Repair of Damage in Double-stranded ϕX174 (RF) DNA Due to Radiation-induced Water Radicals

1984 • 25 citations

Characterization of antibodies to dihydrothymine, a radiolysis product of DNA

1989 • 20 citations

SOS processing of unique oxidative DNA damages in Escherichia coli

1989 • 20 citations