Oxidative and nitrosative stress in ammonia neurotoxicity

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1992 • 692 citations

Peripheral-Type Benzodiazepine/Diazepam Binding Inhibitor Receptor: Biological Role in Steroidogenic Cell Function*

1993 • 404 citations

Advances in cellular neurobiology, 2

1982 • 376 citations

Ammonia‐induced production of free radicals in primary cultures of rat astrocytes

2001 • 298 citations

Hepatic Encephalopathy: An Update of Pathophysiologic Mechanisms

1999 • 296 citations

Ammonia induces MK‐801‐sensitive nitration and phosphorylation of protein tyrosine residues in rat astrocytes

2002 • 283 citations

Inhibition of brain glutamine accumulation prevents cerebral edema in hyperammonemic rats

1991 • 260 citations

Superoxide Production and Antioxidant Enzymes in Ammonia Intoxication in Rats

1997 • 215 citations

Inhibition of glutamine synthetase reduces ammonia-induced astrocyte swelling in rat

1996 • 209 citations

Sodium benzoate in the treatment of acute hepatic encephalopathy: A double-blind randomized trial

1992 • 180 citations

Cerebral blood flow and the development of ammonia-induced brain edema in rats after portacaval anastomosis

1999 • 178 citations

Ammonia induces the mitochondrial permeability transition in primary cultures of rat astrocytes

2001 • 173 citations

Blocking NMDA receptors prevents the oxidative stress induced by acute ammonia intoxication

1999 • 159 citations

Morphologic Effects of Ammonia on Primary Astrocyte Cultures. I. Light Microscopic Studies

1985 • 158 citations

The hydroxyl radical scavengers dimethylsulfoxide and dimethylthiourea protect rats against thioacetamide-induced fulminant hepatic failure

1999 • 141 citations

The Astrocyte in Liver Disease

1981 • 140 citations

Cerebral energy metabolism in hepatic encephalopathy and hyperammonemia.

2001 • 135 citations

Effect of Reducing Brain Glutamine Synthesis on Metabolic Symptoms of Hepatic Encephalopathy

1993 • 108 citations

Molecular and functional properties of mitochondrial benzodiazepine receptors

1995 • 99 citations

Induction of the mitochondrial permeability transition in cultured astrocytes by glutamine

2003 • 89 citations

Nitroarginine, an inhibitor of nitric oxide synthetase, attenuates ammonia toxicity and ammonia-induced alterations in brain metabolism

1995 • 86 citations

Morphologic Effects of Ammonia on Primary Astrocyte Cultures. II. Electron Microscopic Studies

1985 • 85 citations

Increased neuronal nitric oxide synthase expression in brain following portacaval anastomosis

1997 • 80 citations

Effects on free radical generation by ligands of the peripheral benzodiazepine receptor in cultured neural cells

2002 • 79 citations

The Peripheral Benzodiazepine Receptor and Neurosteroids in Hepatic Encephalopathy

1997 • 78 citations

Increased Nitric Oxide Synthase Activities and <scp>l</scp>‐[³H]Arginine Uptake in Brain Following Portacaval Anastomosis

1995 • 77 citations

GeneChip® analysis shows altered mRNA expression of transcripts of neurotransmitter and signal transduction pathways in the cerebral cortex of portacaval shunted rats

2002 • 77 citations

Induction of permeability transition and swelling of rat brain mitochondria by glutamine.

2000 • 53 citations

Pathophysiology of brain edema in fulminant hepatic failure, revisited.

2001 • 52 citations

The “peripheral-type” benzodiazepine (omega 3) receptor in hyperammonemic disorders

2002 • 52 citations

Astrocytes and Ammonia in Hepatic Encephalopathy

2002 • 22 citations

Effect of Antioxidants on Ammonia Induced Cns-Renal Pathobiology in Sheep

1994 • 22 citations

Astrocytes in the aging brain

2002 • 12 citations

Role of oxidative stress in the ammonia‐induced mitochondrial permeability transition in cultured astrocytes

2002 • 4 citations