Heterogeneous synthetic phenotype of cloned scleroderma fibroblasts may be due to aberrant regulation in the synthesis of connective tissues

Use of a mixture of proteinase-free collagenases for the specific assay of radioactive collagen in the presence of other proteins

1971 • 1,396 citations

Limiting dilution assays for the determination of immunocompetent cell frequencies. I. Data analysis.

1981 • 1,281 citations

Increased Collagen Synthesis by Scleroderma Skin Fibroblasts In Vitro A POSSIBLE DEFECT IN THE REGULATION OR ACTIVATION OF THE SCLERODERMA FIBROBLAST

1974 • 545 citations

Skin thickness and collagen content in progressive systemic sclerosis and localized scleroderma

1979 • 331 citations

CONNECTIVE TISSUE SYNTHESIS BY SCLERODERMA SKIN FIBROBLASTS IN CELL CULTURE

1972 • 201 citations

Heterogeneity of Normal Human Diploid Fibroblasts: Isolation and Characterization of One Phenotype

1984 • 175 citations

Fibroblast selection in scleroderma

1982 • 168 citations

Increased collagen accumulation in dermal fibroblast cultures from patients with progressive systemic sclerosis (scleroderma).

1978 • 154 citations

Glycosaminoglycans in Scleroderma and Scleredema

1972 • 114 citations

Fibroblast prostaglandin E2 synthesis. Persistence of an abnormal phenotype after short-term exposure to mononuclear cell products.

1983 • 106 citations

Classification and Nomenclature of Progressive Systemic Sclerosis (Scleroderma)

1979 • 102 citations

Clonal heterogeneity in the fibroblast response to mononuclear cell derived mediators

1984 • 76 citations

Progressive systemic sclerosis (PSS, scleroderma) dermal fibroblasts synthesize increased amounts of glycosaminoglycan.

1983 • 71 citations

Procollagen gene expression by scleroderma fibroblasts in culture. inhibition of collagen production and reduction of proα(i) and proα1(III) collagen messenger RNA steady‐state levels by retinoids

1987 • 69 citations

Soluble mediators from mononuclear cells increase the synthesis of glycosaminoglycan by dermal fibroblast cultures derived from normal subjects and progressive systemic sclerosis patients

1985 • 58 citations

Replication and phenotypic expression of control and scleroderma human fibroblasts: responses to growth factors.

1982 • 53 citations

Activation of type I collagen genes in cultured scleroderma fibroblasts

1985 • 40 citations

Products of activated mononuclear cells modulate accumulation of collagen by normal dermal and scleroderma fibroblasts in culture.

1984 • 35 citations

Persistence of scleroderma‐like phenotype in normal fibroblasts after prolonged exposure to soluble mediators from mononuclear cells

1986 • 33 citations

Connective tissue in scleroderma. A biochemical study on the correlation of fractionated glycosaminoglycans and collagen in human skin

1971 • 28 citations

Collagenase Production by Cloned Populations of Rabbit Synovial Fibroblasts

1981 • 26 citations