Cellular model of proximal tubule NaCl and NaHCO3 absorption

Modifier role of internal H+ in activating the Na+–H+ exchanger in renal microvillus membrane vesicles

1982 • 681 citations

Sodium/proton antiport in brush-border-membrane vesicles isolated from rat small intestine and kidney

1976 • 665 citations

Intracellular pH regulation in the renal proximal tubule of the salamander. Basolateral HCO3- transport.

1983 • 549 citations

Localization of a proton-pumping ATPase in rat kidney.

1988 • 343 citations

Rheogenic sodium-bicarbonate cotransport in the peritubular cell membrane of rat renal proximal tubule

1985 • 288 citations

Sodium and potassium ion pump in kidney tubules.

1980 • 285 citations

Homocellular regulatory mechanisms in sodium-transporting epithelia: avoidance of extinction by “flush-through”

1981 • 273 citations

Mechanism of basolateral membrane H+/OH-/HCO-3 transport in the rat proximal convoluted tubule. A sodium-coupled electrogenic process.

1985 • 266 citations

Carbon dioxide causes exocytosis of vesicles containing H+ pumps in isolated perfused proximal and collecting tubules.

1985 • 247 citations

Insulin stimulates volume absorption in the rabbit proximal convoluted tubule.

1987 • 246 citations

Na+/HCO3-co-transport in basolateral membrane vesicles isolated from rabbit renal cortex.

1986 • 237 citations

Angiotensin II stimulates both Na(+)-H+ exchange and Na+/HCO3- cotransport in the rabbit proximal tubule.

1990 • 229 citations

Structure, function and regulation of Na,K-ATPase in the kidney

1986 • 193 citations

Role of the Na+/H+ antiporter in rat proximal tubule bicarbonate absorption.

1987 • 176 citations

Stoichiometry of Na+-HCO-3 cotransport in basolateral membrane vesicles isolated from rabbit renal cortex.

1987 • 174 citations

Chronic metabolic acidosis causes an adaptation in the apical membrane Na/H antiporter and basolateral membrane Na(HCO3)3 symporter in the rat proximal convoluted tubule.

1988 • 143 citations

Chloride/formate exchange with formic acid recycling: a mechanism of active chloride transport across epithelial membranes.

1985 • 130 citations

Chloride transport across the basolateral cell membrane of theNecturus proximal tubule: Dependence on bicarbonate and sodium

1983 • 129 citations

Parallel adaptation of the rabbit renal cortical sodium/proton antiporter and sodium/bicarbonate cotransporter in metabolic acidosis and alkalosis.

1987 • 127 citations

Bicarbonate transport by isolated perfused rabbit proximal convoluted tubules

1977 • 119 citations

Angiotensin II stimulation of Na(+)-H+ exchange in proximal tubule cells

1990 • 119 citations

An ATP-driven proton pump in brush-border membranes from rat renal cortex

1982 • 115 citations

Bicarbonate and fluid absorption by renal proximal straight tubules

1977 • 109 citations

Chloride Uptake by Brush Border Membrane Vesicles Isolated from Rabbit Renal Cortex

1981 • 107 citations

Apical Na+/H+ antiporter and glycolysis-dependent H+-ATPase regulate intracellular pH in the rabbit S3 proximal tubule.

1987 • 105 citations

Adaptation of Na+-H+ exchange in renal microvillus membrane vesicles. Role of dietary protein and uninephrectomy.

1984 • 104 citations

Ionic mechanism of Na+-HCO3− cotransport in rabbit renal basolateral membrane vesicles

1989 • 100 citations

Cell pH in the rat proximal convoluted tubule. Regulation by luminal and peritubular pH and sodium concentration.

1986 • 94 citations

Basolateral membrane Cl/HCO3 exchange in the rat proximal convoluted tubule. Na-dependent and -independent modes.

1987 • 93 citations

Control mechanisms of bicarbonate transport across the rat proximal convoluted tubule

1982 • 92 citations

Na+/H+ antiporter of brush border vesicles: studies with acridine orange uptake

1982 • 92 citations

Active transport potentials, membrane diffusion potentials and streaming potentials across rat kidney proximal tubule

1974 • 91 citations

Electrogenic sodium/bicarbonate cotransport in rabbit renal cortical basolateral membrane vesicles.

1986 • 88 citations

Relationship between sodium and bicarbonate transport in the rat proximal convoluted tubule

1981 • 78 citations

Electrophysiology of basolateral bicarbonate transport in the rabbit proximal tubule

1986 • 78 citations

Intrinsic differences in various segments of the proximal convoluted tubule.

1976 • 75 citations

Presence of Bicarbonate Stimulated ATPase in the Brush Border Microvillus Membranes of the Proximal Tubule

1974 • 74 citations

HCO3- transport in basolateral membrane vesicles isolated from rat renal cortex.

1987 • 73 citations

Metabolic acidosis and parathyroidectomy increase Na+-H+ exchange in brush border vesicles

1983 • 72 citations

Effect of formate on volume reabsorption in the rabbit proximal tubule.

1987 • 72 citations

Effect of luminal bicarbonate concentration on proximal acidification in the rat

1982 • 71 citations

Effects of Anion-Transport Inhibitors on NaCl Reabsorption in the Rat Superficial Proximal Convoluted Tubule

1979 • 71 citations

Increased Vmax for Na+/H+ antiporter activity in proximal tubule brush border vesicles from rabbits with metabolic acidosis

1984 • 68 citations

Effects of extracellular fluid volume and plasma bicarbonate concentration on proximal acidification in the rat.

1983 • 67 citations

KCl co-transport across the basolateral membrane of rabbit renal proximal straight tubules.

1988 • 65 citations

Active and passive components of chloride transport in the rat proximal convoluted tubule.

1985 • 63 citations

Interaction of chloride and bicarbonate transport across the basolateral membrane of rabbit proximal straight tubule. Evidence for sodium coupled chloride/bicarbonate exchange.

1988 • 59 citations

Effect of inhibitors and diuretics on electrical potential differences in rat kidney proximal tubule

1975 • 56 citations

Effects of CO2 and acetazolamide on bicarbonate and fluid transport in rabbit proximal tubules

1981 • 51 citations

Transport of H+ against electrochemical gradients in turtle urinary bladder

1977 • 51 citations

Influence of peritubular protein on solute absorption in the rabbit proximal tubule. A specific effect on NaCl transport.

1981 • 49 citations

Absence of Cl-OH exchange and NaCl cotransport in rabbit renal microvillus membrane vesicles

1984 • 48 citations

Apical membrane chloride/base exchange in the rat proximal convoluted tubule.

1987 • 47 citations

Renal brush-border chloride transport mechanisms characterized using a fluorescent indicator

1988 • 45 citations

Chronic hypercapnia stimulates proximal bicarbonate reabsorption in the rat.

1984 • 45 citations

Relation of ATPases in rat renal brush-border membranes to ATP-driven H+ secretion

1989 • 45 citations

Na-HCO3 cotransport and Na-H antiporter in chronic respiratory acidosis and alkalosis

1989 • 44 citations

Mechanisms of adaptation to chronic respiratory acidosis in the rabbit proximal tubule.

1989 • 43 citations

Kinetic transport model for cellular regulation of pH and solute concentration in the renal proximal tubule

1987 • 37 citations

Mechanism of coupling between Cl− and OH− transport in renal brush-border membranes

1986 • 37 citations

K-Cl transport systems in rabbit renal basolateral membrane vesicles

1987 • 36 citations

Intracellular pH regulation in the S3 segment of the rabbit proximal tubule in HCO3- -free solutions.

1988 • 35 citations

Early enhancement of fluid transport in rabbit proximal straight tubules after loss of contralateral renal excretory function.

1983 • 35 citations

Chronic hypercapnia enhances Vmax of Na-H antiporter of renal brush-border membranes

1987 • 34 citations

Evidence for coupled sodium/hydrogen exchange in the rat superficial proximal convoluted tubule

1982 • 34 citations

Contributions of cellular leak pathways to net NaHCO3 and NaCl absorption.

1989 • 30 citations

Evidence for electroneutral chloride transport in rabbit renal cortical brush border membrane vesicles

1984 • 29 citations

Basolateral membrane Na(+)-independent Cl-/HCO3- exchange in the inner stripe of the rabbit outer medullary collecting tubule.

1990 • 29 citations

Mechanism of bicarbonate exit across basolateral membrane of the rabbit proximal convoluted tubule

1984 • 23 citations

Effect of luminal chloride on cell pH in rabbit proximal tubule

1988 • 21 citations

Uninephrectomy and dietary protein affect fluid absorption in rabbit proximal straight tubules

1987 • 17 citations

Sodium-bicarbonate cotransport occurs in rat kidney cortical membranes but not in rat small intestinal basolateral membranes

1987 • 17 citations

Electrical effects of acidification in the rabbit proximal convoluted tubule

1981 • 11 citations

A micropuncture study of HCO3 reabsorption by the hypertrophied proximal tubule.

1978 • 8 citations

Activation of Cl−/OH− exchange by parachloromercuribenzoic acid in rabbit renal brush-border membranes

1989 • 7 citations

Hyperfiltration increases apical membrane ap sodium hydrogen antiporter and basolateral membrane b1 sodium bicarbonate symporter activities in the rat proximal convoluted tubule pct

1989 • 2 citations