Identification of a Novel Growth Factor-like Lipid, 1-O-cis-Alk-1′-enyl-2-lyso-sn-glycero-3-phosphate (Alkenyl-GP) That Is Present in Commercial Sphingolipid Preparations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUES

1957 • 63,238 citations

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 47,127 citations

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 21,307 citations

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

1992 • 4,454 citations

The Role of Polyamines in the Neutralization of Bacteriophage Deoxyribonucleic Acid

1960 • 2,598 citations

Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate

1996 • 1,493 citations

Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens

1993 • 879 citations

Lysophosphatidate-induced cell proliferation: Identification and dissection of signaling pathways mediated by G proteins

1989 • 846 citations

Techniques of Lipidology

1973 • 777 citations

Ventricular zone gene-1 (vzg-1) encodes a lysophosphatidic acid receptor expressed in neurogenic regions of the developing cerebral cortex.

1996 • 727 citations

Sphingolipid metabolism and cell growth regulation

1996 • 709 citations

Methods for methanolysis of sphingolipids and direct determination of long‐chain bases by gas chromatography

1965 • 533 citations

Lysophosphatidic acid: G-protein signalling and cellular responses

1997 • 492 citations

Pertussis toxin-sensitive activation of p21ras by G protein-coupled receptor agonists in fibroblasts.

1993 • 377 citations

Lysophosphatidates bound to serum albumin activate membrane currents in Xenopus oocytes and neurite retraction in PC12 pheochromocytoma cells.

1992 • 355 citations

Lysophospholipids activate ovarian and breast cancer cells

1995 • 289 citations

Lysophosphatidic acid stimulates mitogen-activated protein kinase activation via a G-protein-coupled pathway requiring p21ras and p74raf-1.

1993 • 233 citations

Sphingosine 1-phosphate, a specific endogenous signaling molecule controlling cell motility and tumor cell invasiveness.

1992 • 223 citations

Induction of in Vitro Tumor Cell Invasion of Cellular Monolayers by Lysophosphatidic Acid or Phospholipase D

1993 • 185 citations

Identification of plasmalogen as the major phospholipid constituent of cardiac sarcoplasmic reticulum

1985 • 184 citations

A family of phospholipid autacoids: Occurrence, metabolism and bioactions

1995 • 180 citations

Molecular cloning of a high-affinity receptor for the growth factor-like lipid mediator lysophosphatidic acid from Xenopus oocytes

1996 • 173 citations

A reagent for the non-destructive location of steroids and some other lipophilic materials on silica gel thin-layer chromatograms

1971 • 152 citations

Lysophosphatidic acid possesses dual action in cellproliferation.

1994 • 151 citations

Regulation of Mitogen-activated Protein Kinase Phosphatase-1 Expression by Extracellular Signal-related Kinase-dependent and Ca2+-dependent Signal Pathways in Rat-1 Cells

1997 • 121 citations

Edg-2/Vzg-1 Couples to the Yeast Pheromone Response Pathway Selectively in Response to Lysophosphatidic Acid

1998 • 118 citations

Signaling pathways for sphingosylphosphorylcholine-mediated mitogenesis in Swiss 3T3 fibroblasts.

1993 • 117 citations

Lysophosphatidic acid-induced Ca2+ mobilization in human A431 cells: structure-activity analysis

1995 • 113 citations

A Lysophospholipase D Pathway in the Metabolism of Ether-linked Lipids in Brain Microsomes

1974 • 113 citations

Signalling properties of lysophosphatidic acid

1993 • 112 citations

Sphingosylphosphorylcholine is a remarkably potent mitogen for a variety of cell lines

1991 • 109 citations

Growth factor-like phospholipids generated after corneal injury

1998 • 107 citations

Sphingosylphosphorylcholine Rapidly Induces Tyrosine Phosphorylation of p125 and Paxillin, Rearrangement of the Actin Cytoskeleton and Focal Contact Assembly

1995 • 103 citations

A serum factor that activates the phosphatidylinositol phosphate signaling system in Xenopus oocytes.

1990 • 98 citations

Responses to sphingosine-1-phosphate in X. laevis oocytes: similarities with lysophosphatidic acid signaling

1993 • 94 citations

Alkoxylipids. II. “Neutral plasmalogens” in the liver oil of the ratfish (Hydrolagus colliei)

1966 • 92 citations

Effect of lysophospholipids on signaling in the human Jurkat T cell line

1995 • 88 citations

Sphingosylphosphorylcholine Activation of Mitogen-activated Protein Kinase in Swiss 3T3 Cells Requires Protein Kinase C and a Pertussis Toxin-sensitive G Protein

1995 • 75 citations

Stimulated neutrophils produce an ethanolamine plasmalogen analog of platelet-activating factor.

1987 • 64 citations

Studies of lysophospholipase D of rat liver and other tissues

1977 • 64 citations

Differential regulation of extracellular signal-regulated protein kinase 1 and Jun N-terminal kinase 1 by Ca2+ and protein kinase C in endothelin-stimulated Rat-1 cells

1997 • 49 citations

Specificities of alkaline and acid phosphatases in the dephosphorylation of phospholipids

1970 • 49 citations

Inhibition of Cell Proliferation by a Unique Lysophosphatidic Acid, PHYLPA, Isolated from Physarum polycephalum: Signaling Events of Antiproliferative Action by PHYLPA.

1993 • 41 citations

Prevention of rat neonatal cardiomyocyte apoptosis induced by simulated in vitro ischemia and reperfusion

1997 • 41 citations

Sphingosylphosphocholine, a signaling molecule which accumulates in Niemann-Pick disease type A, stimulates DNA-binding activity of the transcription activator protein AP-1.

1995 • 41 citations

Age differences in the acyl group composition of phosphoglycerides in myelin isolated from the brain of the rhesus monkey

1973 • 31 citations

Lysoplasmalogenase–A Microsomal Enzyme from Rat Brain

1982 • 24 citations

Modulation of cytosolic protein phosphorylation by sphingosylphosphorylcholine

1994 • 15 citations

Plasmalogens: Their metabolism and central role in the production of lipid mediators

1997 • 8 citations

A novel approach to structure proof of glyceryl ether-containing glycerophospholipids. Base-catalyzed methanolysis of platelet-activating factor (AGEPC) at 60 degrees C

1985 • 7 citations