A Cluster of Basic Residues in the Carboxyl-terminal Tail of the Short Metabotropic Glutamate Receptor 1 Variants Impairs Their Coupling to Phospholipase C
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References (48)
PHARMACOLOGY AND FUNCTIONS OF METABOTROPIC GLUTAMATE RECEPTORS
1997 • 3,070 citations
Cloning and characterization of an extracellular Ca2+-sensing receptor from bovine parathyroid
1993 • 2,625 citations
The metabotropic glutamate receptors: Structure and functions
1995 • 2,269 citations
A mutation-induced activated state of the beta 2-adrenergic receptor. Extending the ternary complex model.
1993 • 1,213 citations
Sequence and expression of a metabotropic glutamate receptor
1991 • 1,200 citations
Differential signal transduction by five splice variants of the PACAP receptor
1993 • 1,185 citations
Homer: a protein that selectively binds metabotropic glutamate receptors
1997 • 1,058 citations
Expression cloning of GABAB receptors uncovers similarity to metabotropic glutamate receptors
1997 • 1,020 citations
A family of metabotropic glutamate receptors
1992 • 873 citations
Molecular characterization of a novel metabotropic glutamate receptor mGluR5 coupled to inositol phosphate/Ca2+ signal transduction.
1992 • 814 citations
Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1
1994 • 730 citations
Metabotropic glutamate receptors: Synaptic transmission, modulation, and plasticity
1994 • 713 citations
The ligand-binding domain in metabotropic glutamate receptors is related to bacterial periplasmic binding proteins
1993 • 695 citations
Constitutive activation of the alpha 1B-adrenergic receptor by all amino acid substitutions at a single site. Evidence for a region which constrains receptor activation.
1992 • 587 citations
Cloning, Expression, and Gene Structure of a G Protein-Coupled Glutamate Receptor from Rat Brain
1991 • 524 citations
The two-state model of receptor activation
1995 • 492 citations
Control of calcium oscillations by phosphorylation of metabotropic glutamate receptors
1996 • 289 citations
Molecular, functional, and pharmacological characterization of the metabotropic glutamate receptor type 5 splice variants: comparison with mGluR1
1995 • 275 citations
Differential activation of intracellular effector by two isoforms of human neurokinin-1 receptor.
1992 • 242 citations
Constitutively active mutants of the alpha 2-adrenergic receptor
1993 • 234 citations
Alternative splicing generates metabotropic glutamate receptors inducing different patterns of calcium release in Xenopus oocytes.
1992 • 226 citations
Subcellular patterns of calcium release determined by G protein-specific residues of muscarinic receptors
1991 • 207 citations
Domains involved in the specificity of G protein activation in phospholipase C-coupled metabotropic glutamate receptors.
1994 • 197 citations
Distinct sequence elements control the specificity of G protein activation by muscarinic acetylcholine receptor subtypes.
1990 • 192 citations
Get receptive to metabotropic glutamate receptors
1995 • 157 citations
Mutation of Asn111 in the Third Transmembrane Domain of the AT1A Angiotensin II Receptor Induces Its Constitutive Activation
1997 • 155 citations
The Second Intracellular Loop of Metabotropic Glutamate Receptor 1 Cooperates with the Other Intracellular Domains to Control Coupling to G-proteins
1996 • 155 citations
Role of the large extracellular domain of metabotropic glutamate receptors in agonist selectivity determination.
1993 • 141 citations
Changes in the carboxyl-terminal domain of metabotropic glutamate receptor 1 by alternative splicing generate receptors with differing agonist-independent activity.
1996 • 139 citations
Light-induced binding of guanosinetriphosphatase to bovine photoreceptor membranes: effect of limited proteolysis of the membranes
1981 • 136 citations
Identification of the Amino Acid Subsets Accounting for the Ligand Binding Specificity of a Glutamate Receptor
1996 • 120 citations
Coupling of metabotropic glutamate receptors 2 and 4 to G alpha 15, G alpha 16, and chimeric G alpha q/i proteins: characterization of new antagonists.
1996 • 105 citations
A Variant of Metabotropic Glutamate Receptor Subtype 5: An Evolutionally Conserved Insertion with No Termination Codon
1993 • 103 citations
A Comparison of Two Alternatively Spliced Forms of a Metabotropic Glutamate Receptor Coupled to Phosphoinositide Turnover
1993 • 101 citations
Characterization of two alternatively spliced forms of a metabotropic glutamate receptor in the central nervous system of the rat
1994 • 69 citations
Charged amino acids required for signal transduction by the m3 muscarinic acetylcholine receptor.
1993 • 67 citations
The C‐Terminal Domain of the mGluR1 Metabotropic Glutamate Receptor Affects Sensitivity to Agonists
1996 • 67 citations
Truncation of the extended carboxyl-terminal domain increases the expression and regulatory activity of the avian beta-adrenergic receptor
1991 • 64 citations
Depalmitylation with hydroxylamine alters the functional properties of rhodopsin.
1991 • 61 citations
A C‐terminally truncated human parathyroid hormone receptor is functional and activates multiple G proteins
1994 • 58 citations
Effects of Carboxy-Terminal Truncation on the Stability and G Protein-Coupling Activity of Bovine Rhodopsin
1994 • 56 citations
HmGlu1d, a novel splice variant of the human type I metabotropic glutamate receptor
1996 • 53 citations
Truncation of the Thyrotropin-releasing Hormone Receptor Carboxyl Tail Causes Constitutive Activity and Leads to Impaired Responsiveness in Xenopus Oocytes and AtT20 Cells
1995 • 43 citations
The rat mGlu1d receptor splice variant shares functional properties with the other short isoforms of mGlu1 receptor
1997 • 31 citations
Activation of rod outer segment phosphodiesterase by enzymatically altered rhodopsin: A regulatory role for the carboxyl terminus of rhodopsin
1984 • 29 citations
Carboxyl domain of glutamate receptor directs its coupling to metabolic pathways
1993 • 22 citations
Is the heterologous expression of metabotropic glutamate receptors (mGluRs) an appropriate method to study the mGluR function? Experience with human embryonic kidney 293 cells transfected with mGluR1
1994 • 15 citations
Alfred Benzon Symposium 39: Structure and Function of 7TM Receptors
1997 • 3 citations