Cellular immune therapy for refractory cancers: novel therapeutic strategies

Nonmyeloablative Stem Cell Transplantation and Cell Therapy as an Alternative to Conventional Bone Marrow Transplantation With Lethal Cytoreduction for the Treatment of Malignant and Nonmalignant Hematologic Diseases

1998 • 1,984 citations

Nonmyeloablative Stem Cell Transplantation and Cell Therapy as an Alternative to Conventional Bone Marrow Transplantation With Lethal Cytoreduction for the Treatment of Malignant and Nonmalignant Hematologic Diseases

1998 • 1,765 citations

Donor leukocyte transfusions for treatment of recurrent chronic myelogenous leukemia in marrow transplant patients

1990 • 1,544 citations

Prevention of Graft Versus Host Disease by Inactivation of Host Antigen-Presenting Cells

1999 • 1,218 citations

Placental Blood as a Source of Hematopoietic Stem Cells for Transplantation into Unrelated Recipients

1996 • 1,053 citations

Outcomes after Transplantation of Cord Blood or Bone Marrow from Unrelated Donors in Adults with Leukemia

2004 • 1,042 citations

Regression of Metastatic Renal-Cell Carcinoma after Nonmyeloablative Allogeneic Peripheral-Blood Stem-Cell Transplantation

2000 • 1,029 citations

Processing and cryopreservation of placental/umbilical cord blood for unrelated bone marrow reconstitution.

1995 • 823 citations

In vivo CAMPATH-1H prevents graft-versus-host disease following nonmyeloablative stem cell transplantation

2000 • 525 citations

Melphalan and purine analog–containing preparative regimens: reduced-intensity conditioning for patients with hematologic malignancies undergoing allogeneic progenitor cell transplantation

2001 • 512 citations

Induction of Graft-versus-Host Disease as Immunotherapy for Relapsed Chronic Myeloid Leukemia

1994 • 510 citations

Rapid and complete donor chimerism in adult recipients of unrelated donor umbilical cord blood transplantation after reduced-intensity conditioning

2003 • 416 citations

Mixed lymphohaemopoietic chimerism and graft-ver suslymphoma effects after non-myeloablative therapy and HLA-mismatched bone-marrow transplantation

1999 • 405 citations

Nonablative versus reduced-intensity conditioning regimens in the treatment of acute myeloid leukemia and high-risk myelodysplastic syndrome: dose is relevant for long-term disease control after allogeneic hematopoietic stem cell transplantation

2004 • 375 citations

Nonablative allogeneic hematopoietic transplantation as adoptive immunotherapy for indolent lymphoma: low incidence of toxicity, acute graft-versus-host disease, and treatment-related mortality

2001 • 373 citations

Long-term engraftment of normal and post-5-fluorouracil murine marrow into normal nonmyeloablated mice [see comments]

1993 • 316 citations

Prospective Trial of Chemotherapy and Donor Leukocyte Infusions for Relapse of Advanced Myeloid Malignancies After Allogeneic Stem-Cell Transplantation

2002 • 265 citations

Intentional induction of mixed chimerism and achievement of antitumor responses after nonmyeloablative conditioning therapy and HLA-matched donor bone marrow transplantation for refractory hematologic malignancies

2000 • 259 citations

Fusion Cell Vaccination of Patients with Metastatic Breast and Renal Cancer Induces Immunological and Clinical Responses

2004 • 239 citations

Bigger is better: maternal and neonatal predictors of hematopoietic potential of umbilical cord blood units

2001 • 231 citations

Nonmyeloablative conditioning followed by hematopoietic cell allografting and donor lymphocyte infusions for patients with metastatic renal and breast cancer

2002 • 207 citations

Outcomes After Transplantation of Cord Blood or Bone Marrow From Unrelated Donors in Adults With Leukemia

2005 • 169 citations

Prospective Trial of Chemotherapy and Donor Leukocyte Infusions for Relapse of Advanced Myeloid Malignancies After Allogeneic Stem-Cell Transplantation

2002 • 165 citations

Cells Capable of Bone Production Engraft from Whole Bone Marrow Transplants in Nonablated Mice

1999 • 157 citations

Allogeneic hematopoietic stem cell transplantation from family members other than HLA-identical siblings over the last decade (1991-2000)

2003 • 150 citations

Impact of prophylactic donor leukocyte infusions on mixed chimerism, graft-versus-host disease, and antitumor response in patients with advanced hematologic malignancies treated with nonmyeloablative conditioning and allogeneic bone marrow transplantation

2003 • 146 citations

Lymphohematopoietic Engraftment in Minimally Myeloablated Hosts

1998 • 133 citations

Graft-Versus-Tumor Induction With Donor Leukocyte Infusions as Primary Therapy for Patients With Malignancies

1999 • 131 citations

Long-term follow-up of patients who achieved complete remission after donor leukocyte infusions

1999 • 123 citations

Nonmyeloablative haploidentical stem-cell transplantation using anti-CD2 monoclonal antibody (MEDI-507)-based conditioning for refractory hematologic malignancies

2003 • 117 citations

Lymphohematopoietic Engraftment in Minimally Myeloablated Hosts

1998 • 107 citations

Murine marrow cellularity and the concept of stem cell competition: geographic and quantitative determinants in stem cell biology

2004 • 99 citations

Antitumor effect of donor marrow graft rejection induced by recipient leukocyte infusions in mixed chimeras prepared with nonmyeloablative conditioning: critical role for recipient-derived IFN-γ

2003 • 83 citations

Anti‐tumour response despite loss of donor chimaerism in patients treated with non‐myeloablative conditioning and allogeneic stem cell transplantation

2005 • 82 citations

Allogeneic hematopoietic stem cell transplantation in ovarian carcinoma: results of five patients

2002 • 81 citations

Tumour cell/dendritic cell fusions as a vaccination strategy for multiple myeloma

2004 • 78 citations

Melphalan and purine analog–containing preparative regimens: reduced-intensity conditioning for patients with hematologic malignancies undergoing allogeneic progenitor cell transplantation

2001 • 76 citations

Successful allogeneic stem cell transplantation with nonmyeloablative conditioning in patients with relapsed hematologic malignancy following autologous stem cell transplantation

2001 • 66 citations

Nonmyeloablative bone marrow transplantation: infectious complications in 65 recipients of HLA-identical and mismatched transplants

2003 • 61 citations

The probability of finding a suitable related donor for bone marrow transplantation in extended families [see comments]

1996 • 59 citations

Costimulatory approaches to adoptive immunotherapy

1998 • 57 citations

Prior chemotherapy and allograft CD34+ dose impact donor engraftment following nonmyeloablative allogeneic stem cell transplantation in patients with solid tumors

2003 • 54 citations

Potential allogeneic graft-versus-tumor effect in a patient with ovarian cancer

2000 • 52 citations

Allogeneic chimerism with low-dose irradiation, antigen presensitization, and costimulator blockade in H-2 mismatched mice

2001 • 52 citations

Low-dose total body irradiation followed by allogeneic lymphocyte infusion may induce remission in patients with refractory hematologic malignancy

2002 • 49 citations

Allogeneic cell therapy for patients who relapse after autologous stem cell transplantation

2001 • 47 citations

Early host CD8 T-cell recovery and sensitized anti-donor interleukin-2–producing and cytotoxic T-cell responses associated with marrow graft rejection following nonmyeloablative allogeneic bone marrow transplantation

2003 • 45 citations

Racial diversity with high nucleated cell counts and CD34 counts achieved in a national network of cord blood banks

2004 • 44 citations

H2‐mismatched transplantation with repetitive cell infusions and CD40 ligand antibody infusions without myeloablation

2002 • 25 citations

Intensive graft-versus-host disease prophylaxis is required after unrelated-donor nonmyeloablative stem cell transplantation

2005 • 14 citations

Donor leukocyte infusions in acute myelogenous leukemia

2003 • 10 citations

Achievement of sustained remissions despite loss of donor chimerism in patients with chemotherapy-refractory non-Hodgkins lymphoma treated with nonmyeloablative conditioning and allogeneic stem cell transplantation

2001 • 7 citations

Enhancing Graft-vs-Tumor (GVT) Activity of Donor Leukocyte Infusions by Ex-Vivo Expansion and Activation with CD3/CD28 Co-Stimulation.

2004 • 3 citations

Mini-Haploidentical Transplantation for Refractory Acute Myeloid Leukemia.

2004 • 2 citations

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