Bone morphogenetic protein receptor-II mutation Arg491Trp causes malignant phenotype of familial primary pulmonary hypertension

Bone morphogenetic proteins: multifunctional regulators of vertebrate development.

1996 • 1,959 citations

Controlling TGF-beta signaling.

2000 • 1,806 citations

Primary Pulmonary Hypertension

1997 • 1,748 citations

Controlling TGF-β signaling

2000 • 1,522 citations

Heterozygous germline mutations in BMPR2, encoding a TGF-β receptor, cause familial primary pulmonary hypertension

2000 • 1,445 citations

Familial Primary Pulmonary Hypertension (Gene PPH1) Is Caused by Mutations in the Bone Morphogenetic Protein Receptor–II Gene

2000 • 1,184 citations

Appetite-Suppressant Drugs and the Risk of Primary Pulmonary Hypertension

1996 • 1,131 citations

Specificity, diversity, and regulation in TGF-beta superfamily signaling.

1999 • 788 citations

Sporadic primary pulmonary hypertension is associated with germline mutations of the gene encoding BMPR-II, a receptor member of the TGF-beta family

2000 • 725 citations

Specificity, diversity, and regulation in TGF‐β superfamily signaling

1999 • 644 citations

Human Type II Receptor for Bone Morphogenic Proteins (BMPs): Extension of the Two-Kinase Receptor Model to the BMPs

1995 • 602 citations

Primary Pulmonary Hypertension

1993 • 307 citations

Pulmonary hypertension in patients with human immunodeficiency virus infection. Comparison with primary pulmonary hypertension.

1994 • 239 citations

Disruption of Transforming Growth Factor β Signaling by a Mutation That Prevents Transphosphorylation within the Receptor Complex

1995 • 217 citations

Signaling Activity of Transforming Growth Factor β Type II Receptors Lacking Specific Domains in the Cytoplasmic Region

1993 • 207 citations

Familial primary pulmonary hypertension: clinical patterns.

1984 • 187 citations

Inhibition of rat vascular smooth muscle proliferation in vitro and in vivo by bone morphogenetic protein-2.

1997 • 160 citations

Human Immunodeficiency Virus Infection and Pulmonary Hypertension: Two New Cases and a Review of 86 Reported Cases

1998 • 137 citations

BMP-2 Gene Expression and Effects on Human Vascular Smooth Muscle Cells

1999 • 125 citations

Signaling activity of transforming growth factor beta type II receptors lacking specific domains in the cytoplasmic region.

1993 • 122 citations

Genetics of pulmonary hypertension: from bench to bedside

2002 • 65 citations

XBMPRII, a novel Xenopus type II receptor mediating BMP signaling in embryonic tissues

1998 • 61 citations

Inactive Type II and Type I Receptors for TGFβ Are Dominant Inhibitors of TGFβ-dependent Transcription

1995 • 54 citations

Truncated Type II Receptor for BMP-4 Induces Secondary Axial Structures in Xenopus Embryos

1995 • 45 citations