Establishment of apoptosis‐inducing monoclonal antibody 2D1 and 2D1‐resistant variants of human T cell lines

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

1990 • 3,817 citations

The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

1991 • 2,815 citations

Social controls on cell survival and cell death

1992 • 2,641 citations

Monoclonal Antibody-Mediated Tumor Regression by Induction of Apoptosis

1989 • 1,739 citations

A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor.

1989 • 1,436 citations

bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes

1991 • 1,223 citations

Induction of bcl-2 expression by epstein-barr virus latent membrane protein 1 protects infected B cells from programmed cell death

1991 • 1,195 citations

Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures

1989 • 1,159 citations

Tumor necrosis factor can induce both apoptic and necrotic forms of cell lysis.

1988 • 889 citations

Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/nerve growth factor receptor superfamily. Sequence identity with the Fas antigen.

1992 • 857 citations

Cooperative interaction between c-myc and bcl-2 proto-oncogenes

1992 • 766 citations

Expression of the bcl-2 oncogene protein is not specific for the 14;18 chromosomal translocation.

1990 • 622 citations

Programmed Cell Death in the Immune System

1991 • 575 citations

DNA fragmentation and cell death is selectively triggered in activated human lymphocytes by Fas antigen engagement

1992 • 392 citations

T cell receptor/CD3-signaling induces death by apoptosis in human T cell receptor gamma delta + T cells.

1991 • 167 citations

TAPA-1, the target of an antiproliferative antibody, is associated on the cell surface with the Leu-13 antigen.

1990 • 149 citations

Apoptosis: mode of cell death induced in T cell leukemia lines by dexamethasone and other agents

1991 • 115 citations

Expression of the APO-1 antigen in Burkitt lymphoma cell lines correlates with a shift towards a lymphoblastoid phenotype

1992 • 97 citations

Dna fragmentation and cell death mediated by t cell antigen receptor/cd3 complex on a leukemia t cell line^*

1989 • 70 citations

Prevalence of antigen receptor variants in human T cell lines and tumors.

1989 • 53 citations

In vitro proliferation and the cytotoxic specificity of a cryopreserved cytotoxic T cell clone reacting against human autologous tumor cells

1992 • 18 citations