Animal Models of BCR/ABL-Induced Leukemias

Induction of Chronic Myelogenous Leukemia in Mice by the P210 ^bcr/abl Gene of the Philadelphia Chromosome

1990 • 2,207 citations

Acute leukaemia in bcr/abl transgenic mice

1990 • 701 citations

Induction of a chronic myelogenous leukemia-like syndrome in mice with v-abl and BCR/ABL.

1990 • 535 citations

bcr-abl, the hallmark of chronic myeloid leukaemia in man, induces multiple haemopoietic neoplasms in mice.

1990 • 371 citations

A bcr-v-abl oncogene induces lymphomas in transgenic mice.

1989 • 125 citations

Blast crisis in a murine model of chronic myelogenous leukemia.

1991 • 119 citations

Differences in oncogenic potency but not target cell specificity distinguish the two forms of the BCR/ABL oncogene.

1991 • 89 citations

Implicating the bcr/abl Gene in the Pathogenesis of Philadelphia Chromosome-Positive Human Leukemia

1991 • 88 citations

Hematologic disease induced in BALB/c mice by a bcr-abl retrovirus is influenced by the infection conditions.

1992 • 63 citations

v-abl causes hematopoietic disease distinct from that caused by bcr-abl.

1991 • 46 citations

Leukemia initiated by hemopoietic stem cells expressing the v-abl oncogene.

1991 • 21 citations