Reaction products from N-methyl-N-nitrosourea and deoxyribonucleic acid containing thymidine residues. Synthesis and identification of a new methylation product, O4-methyl-thymidine

Genetical Implications of the Structure of Deoxyribonucleic Acid

2017 • 1,338 citations

Possible Relevance of O–6 Alkylation of Deoxyguanosine to the Mutagenicity and Carcinogenicity of Nitrosamines and Nitrosamides

1969 • 949 citations

Methylation of ribonucleic acid by the carcinogens dimethyl sulphate, N-methyl-N-nitrosourea and N-methyl-N′-nitro-N-nitrosoguanidine. Comparisons of chemical analyses at the nucleoside and base levels

1972 • 185 citations

Identification of the altered bases in mutated single-stranded DNA

1964 • 176 citations

Alkylation of Phosphates and Stability of Phosphate Triesters in DNA

1972 • 136 citations

Cytotoxicity of alkylating agents towards sensitive and resistant strains of Escherichia coli in relation to extent and mode of alkylation of cellular macromolecules and repair of alkylation lesions in deoxyribonucleic acids

1968 • 116 citations

Inactivation and mutation of coliphage T2 by N-methyl- and N-ethyl-N-nitrosourea

1969 • 109 citations

Ionization of DNA bases or base analogues as a possible explanation of mutagenesis, with special reference to 5-bromodeoxyuridine

1962 • 89 citations

Reaction of alkylating mutagens and carcinogens with nucleic acids: detection and estimation of a small extent of methylation at O-6 of guanine in DNA by methyl methanesulphonate in vitro

1972 • 77 citations

The alkylation of 2′-deoxyguanosine and of thymidine with diazoalkanes. Some observations on O-alkylation

1973 • 73 citations

Nucleic acid related compounds. 1. Methylation and transformation of 4-methoxy-2-pyrimidinone 1-β-D-ribofuranoside into 2'-O-methyl nucleoside components of ribonucleic acid, their analogs, and derivatives

1971 • 41 citations

Analysis of DNA for the formation of 3-methylthymine after administration of dimethylnitrosamine

1972 • 9 citations