COMORBIDITY IN RHEUMATOID ARTHRITIS

Randomized Trial of Estrogen Plus Progestin for Secondary Prevention of Coronary Heart Disease in Postmenopausal Women

1998 • 6,250 citations

Inflammation, Aspirin, and the Risk of Cardiovascular Disease in Apparently Healthy Men

1997 • 5,442 citations

The Effect of Celecoxib, a Cyclooxygenase-2 Inhibitor, in Familial Adenomatous Polyposis

2000 • 2,505 citations

Infliximab (chimeric anti-tumour necrosis factor α monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: a randomised phase III trial

1999 • 2,358 citations

A Comparison of Etanercept and Methotrexate in Patients with Early Rheumatoid Arthritis

2000 • 1,757 citations

Aspirin Use and Reduced Risk of Fatal Colon Cancer

1991 • 1,695 citations

The worldwide problem of osteoporosis: Insights afforded by epidemiology

1995 • 1,390 citations

The mortality of rheumatoid arthritis

1994 • 1,323 citations

Risk for Serious Gastrointestinal Complications Related to Use of Nonsteroidal Anti-inflammatory Drugs

1991 • 1,260 citations

Alendronate for the Prevention and Treatment of Glucocorticoid-Induced Osteoporosis

1998 • 1,256 citations

Postmenopausal Hormone Therapy and Mortality

1997 • 1,184 citations

Aspirin and the Risk of Colorectal Cancer in Women

1995 • 1,116 citations

Glucocorticoid-Induced Osteoporosis: Pathogenesis and Management

1990 • 1,088 citations

Misoprostol Reduces Serious Gastrointestinal Complications in Patients with Rheumatoid Arthritis Receiving Nonsteroidal Anti-Inflammatory Drugs

1995 • 1,071 citations

Anti-inflammatory and Upper Gastrointestinal Effects of Celecoxib in Rheumatoid Arthritis

1999 • 812 citations

Risk of Infectious Complications in Patients Taking Glucocorticosteroids

1989 • 809 citations

Aspirin Use and the Risk for Colorectal Cancer and Adenoma in Male Health Professionals

1994 • 804 citations

A Comparison of Omeprazole with Ranitidine for Ulcers Associated with Nonsteroidal Antiinflammatory Drugs

1998 • 777 citations

Aspirin Use and Lung, Colon, and Breast Cancer Incidence in a Prospective Study

1994 • 746 citations

Adverse Upper Gastrointestinal Effects of Rofecoxib Compared With NSAIDs

1999 • 706 citations

The pathology of posttransplant lymphoproliferative disorders occurring in the setting of cyclosporine A-prednisone immunosuppression.

1988 • 695 citations

The clinical consequences of vertebral compression fracture

1992 • 653 citations

Treatment of Rheumatoid Arthritis with Methotrexate Alone, Sulfasalazine and Hydroxychloroquine, or a Combination of All Three Medications

1996 • 647 citations

Risk factors for coronary artery disease in patients with systemic lupus erythematosus

1992 • 625 citations

Corticosteroid Use and Peptic Ulcer Disease: Role of Nonsteroidal Anti-inflammatory Drugs

1991 • 606 citations

Incidence of Cancer Among Patients With Rheumatoid Arthritis

1993 • 596 citations

Efficacy and Safety of Daily Risedronate in the Treatment of Corticosteroid-Induced Osteoporosis in Men and Women: A Randomized Trial

2000 • 589 citations

C-Reactive Protein Frequently Colocalizes With the Terminal Complement Complex in the Intima of Early Atherosclerotic Lesions of Human Coronary Arteries

1998 • 561 citations

Combination Therapy with Cyclosporine and Methotrexate in Severe Rheumatoid Arthritis

1995 • 530 citations

Consumption of NSAIDs and the Development of Congestive Heart Failure in Elderly Patients

2000 • 518 citations

Lymphoid Neoplasia Associated with the Acquired Immunodeficiency Syndrome (AIDS)

1988 • 518 citations

CORRELATION OF PLASMA INTERLEUKIN 1 LEVELS WITH DISEASE ACTIVITY IN RHEUMATOID ARTHRITIS

1988 • 490 citations

Survival, prognosis, and causes of death in rheumatoid arthritis

1986 • 444 citations

Excess risk of lymphomas, leukemia and myeloma in patients with rheumatoid arthritis

1978 • 434 citations

Association of Adrenocorticosteroid Therapy and Peptic-Ulcer Disease

1983 • 429 citations

Comorbidity and Its Impact on Disability

1989 • 428 citations

Extent of inflammation predicts cardiovascular disease and overall mortality in seropositive rheumatoid arthritis. A retrospective cohort study from disease onset.

1999 • 413 citations

Mortality in rheumatoid arthritis

1995 • 407 citations

Low-Dose Prednisone Induces Rapid Reversible Axial Bone Loss in Patients with Rheumatoid Arthritis

1993 • 404 citations

Antifracture Efficacy of Antiresorptive Agents Are Related to Changes in Bone Density

2000 • 404 citations

THE EPIDEMIOLOGY OF RHEUMATOID ARTHRITIS IN ROCHESTER MINNESOTA: A STUDY OF INCIDENCE, PREVALENCE, AND MORTALITY1

1980 • 400 citations

New Developments in the Pathogenesis and Treatment of Steroid-Induced Osteoporosis

1999 • 390 citations

Rheumatoid arthritis and cancer risk

1996 • 385 citations

The longterm outcomes of rheumatoid arthritis: Work disability: a prospective 18 year study of 823 patients.

1998 • 384 citations

Randomised controlled trial of Helicobacter pylori eradication in patients on non-steroidal anti-inflammatory drugs: HELP NSAIDs study

1998 • 375 citations

Testosterone Therapy in Glucocorticoid-Treated Men

1996 • 373 citations

Length of Life and Cause of Death in Rheumatoid Arthritis

1953 • 364 citations

Risk of Hospitalization for Upper Gastrointestinal Tract Bleeding Associated With Ketorolac, Other Nonsteroidal Anti-inflammatory Drugs, Calcium Antagonists, and Other Antihypertensive Drugs

1998 • 343 citations

The Effects of Hormone Replacement Therapy and Raloxifene on C-Reactive Protein and Homocysteine in Healthy Postmenopausal Women: A Randomized, Controlled Trial1

2000 • 334 citations

Taking mortality in rheumatoid arthritis seriously--predictive markers, socioeconomic status and comorbidity.

1986 • 328 citations

Longterm mortality outcome in patients with rheumatoid arthritis: early presenters continue to do well.

1998 • 327 citations

Effects of cyclophosphamide on the development of malignancy and on long‐term survival of patients with rheumatoid arthritis a 20‐year followup study

1995 • 309 citations

Longterm drug therapy for rheumatoid arthritis in seven rheumatology private practices: II. Second line drugs and prednisone.

1992 • 292 citations

Cigarette smoking and rheumatoid arthritis severity

1997 • 291 citations

Larger increases in bone mineral density during alendronate therapy are associated with a lower risk of new vertebral fractures in women with postmenopausal osteoporosis

1999 • 287 citations

The diagnosis and treatment of posttransplant lymphoproliferative disorders

1988 • 277 citations

Lymphoproliferative cancer and other malignancy in patients with rheumatoid arthritis treated with azathioprine: a 20 year follow up study.

1988 • 274 citations

Malignancy following treatment of rheumatoid arthritis with cyclophosphamide

1987 • 271 citations

Monoreactive high affinity and polyreactive low affinity rheumatoid factors are produced by CD5+ B cells from patients with rheumatoid arthritis.

1988 • 257 citations

Lipid profiles in untreated patients with rheumatoid arthritis.

1999 • 252 citations

Rheumatoid arthritis lung disease. Determinants of radiographic and physiologic abnormalities

1996 • 238 citations

CRP-mediated activation of complement in vivo: assessment by measuring circulating complement-C-reactive protein complexes.

1996 • 233 citations

Use of short‐term efficacy/toxicity tradeoffs to select second‐line drugs in rheumatoid arthritis. A metaanalysis of published clinical trials

1992 • 232 citations

Effect of hormone replacement therapy on bone mass in rheumatoid arthritis patients treated with and without steroids

1994 • 228 citations

Comorbidity: arthritis

2019 • 219 citations

Survival and cause of death in rheumatoid arthritis: a 25-year prospective followup.

1984 • 217 citations

Mortality and survival in rheumatoid arthritis: a 25 year prospective study of 100 patients.

1990 • 212 citations

Work disability in rheumatoid arthritis 10 years after the diagnosis.

1999 • 211 citations

The effect of smoking on clinical, laboratory, and radiographic status in rheumatoid arthritis.

2000 • 210 citations

The costs of rheumatoid arthritis: an international long-term view

2000 • 210 citations

Influence of sulphasalazine, methotrexate, and the combination of both on plasma homocysteine concentrations in patients with rheumatoid arthritis

1999 • 207 citations

Rheumatoid cachexia: depletion of lean body mass in rheumatoid arthritis. Possible association with tumor necrosis factor.

1992 • 200 citations

Abnormally elevated frequency of Epstein-Barr virus-infected B cells in the blood of patients with rheumatoid arthritis.

1984 • 194 citations

The effect of rheumatoid arthritis and steroid therapy on bone density in postmenopausal women

1993 • 193 citations

Osteoporosis in rheumatoid arthritis: safety of low dose corticosteroids.

1986 • 189 citations

Is atherosclerosis a complication of long-term corticosteroid treatment?

1986 • 179 citations

Immunohistologic characterization of synovial membrane lymphocytes in rheumatoid arthritis

1984 • 179 citations

Risk factors for disability among U.S. adults with arthritis

1991 • 178 citations

Cancer morbidity in rheumatoid arthritis.

1984 • 161 citations

Mortality in rheumatoid arthritis: have we made an impact in 4 decades?

1999 • 160 citations

Unresolved Issues in the Role of Cyclooxygenase-2 in Normal Physiologic Processes and Disease

2000 • 159 citations

Rheumatoid arthritis and the risk of malignancy

1997 • 157 citations

MAJOR UNDESIRABLE SIDE-EFFECTS RESULTING FROM PREDNISOLONE AND PREDNISONE

1955 • 154 citations

Predictors of fractures in early rheumatoid arthritis.

1991 • 150 citations

Homocyst(e)ine: an important risk factor for atherosclerotic vascular disease

1997 • 149 citations

The occurrence of malignancies in patients with rheumatoid arthritis treated with cyclophosphamide: a controlled retrospective follow-up.

1983 • 148 citations

Corticosteroid-induced osteoporosis

1993 • 148 citations

Is Methotrexate Therapy for Psoriasis Carcinogenic?

1975 • 146 citations

Toxicity profiles of disease modifying antirheumatic drugs in rheumatoid arthritis.

1991 • 144 citations

Local infectious complications following large joint replacement in rheumatoid arthritis patients treated with methotrexate versus those not treated with methotrexate

1991 • 142 citations

HLA-B27 related arthritis and bowel inflammation. Part 2 Ileocolonoscopy and bowel histology in patients with HLA-B27 related arthritis

2001 • 141 citations

The Effects of Hormone Replacement Therapy and Raloxifene on C-Reactive Protein and Homocysteine in Healthy Postmenopausal Women: A Randomized, Controlled Trial

2000 • 141 citations

Effect of disease modifying agents on the lipid profiles of patients with rheumatoid arthritis

1997 • 139 citations

Cardiovascular Mortality in Patients with Rheumatoid Arthritis

1989 • 136 citations

Cyclical edidronate reverses bone loss of the spine and proximal femur in patients with established corticosteroid-induced osteoporosis

1995 • 135 citations

NSAIDs and Increased Blood Pressure

1997 • 125 citations

Increased Mortality Among Persons with Rheumatoid Arthritis, But Where RA Does Not Appear on Death Certificate:Eleven-Year Follow-Up of an Epidemiological Study

1981 • 115 citations

Processes in atherogenesis: complement activation

1997 • 115 citations

Antifracture Efficacy of Antiresorptive Agents Are Related to Changes in Bone Density

2000 • 113 citations

Dyslipoproteinemia in the course of active rheumatoid arthritis

1992 • 112 citations

Infections during low-dose methotrexate treatmentin rheumatoid arthritis

1995 • 111 citations

Impaired regulation of Epstein-Barr virus-induced lymphocyte proliferation in rheumatoid arthritis is due to a T cell defect.

1981 • 110 citations

The systemic effect of intraarticular administration of corticosteroid on markers of bone formation and bone resorption in patients with rheumatoid arthritis

1996 • 104 citations

The changing face of rheumatoid arthritis therapy: Results of serial surveys

2000 • 100 citations

Effects of low dose corticosteroids on the bone mineral density of patients with rheumatoid arthritis.

1995 • 99 citations

Frequency of Malignant Neoplasms in 248 Long-Term Methotrexate-Treated Psoriatics

1983 • 96 citations

Occurrence of malignant neoplasms in the rochester, minnesota, rheumatoid arthritis cohort

1985 • 95 citations

Should methotrexate be discontinued before elective orthopedic surgery in patients with rheumatoid arthritis?

1991 • 88 citations

Lymphoma in Patients with Rheumatoid Arthritis

1999 • 81 citations

Diastolic function abnormalities in rheumatoid arthritis. Evaluation by echo Doppler transmitral flow and pulmonary venous flow: relation with duration of disease

2000 • 76 citations

The impact of rheumatoid arthritis on the household work performance of women

1991 • 72 citations

CD5+ B cells in autoimmune disease and lymphoid malignancy

1991 • 67 citations

The significance of vascular inflammation in rheumatoid arthritis.

1994 • 64 citations

Effects of supplementation with folic acid and antioxidant vitamins on homocysteine levels and LDL oxidation in coronary patients

2000 • 61 citations

Natural killer (NK) cell activity of peripheral blood, synovial fluid, and synovial tissue lymphocytes from patients with rheumatoid arthritis and juvenile rheumatoid arthritis.

1982 • 60 citations

Rheumatoid arthritis as a risk factor for multiple myeloma: A case-control study

1993 • 57 citations

Testosterone therapy in glucocorticoid-treated men

1996 • 55 citations

Inhibition of neutrophil chemotaxis in methotrexate-treated rheumatoid arthritis patients

1988 • 43 citations

Is methotrexate therapy for psoriasis carcinogenic? A modified retrospective-prospective analysis

1975 • 42 citations

The diagnosis and treatment of post transplant lymphoproliferative disorders

1988 • 38 citations

Persistent bone-sparing effect of interleukin-1 receptor antagonist: A hypothesis on the role of IL-1 in ovariectomy-induced bone loss

1994 • 38 citations

Different defects of T cell regulation of epstein‐barr virus‐induced B cell activation in rheumatoid arthritis

1985 • 34 citations

Helicobacter pylori Infection Increases the Risk of Peptic Ulcers in Chronic Users of Non-steroidal Anti-inflammatory Drugs

1996 • 33 citations

Characterization of recirculating lymphocytes in rheumatoid arthritis patients: selective deficiency of natural killer cells in thoracic duct lymph.

1984 • 33 citations

Long-Term Blood Pressure Changes in Renal Homotransplantation

1978 • 29 citations

The death certificate in rheumatoid arthritis

1967 • 26 citations

Measures of immunologic and inflammatory responses in vitro in rheumatoid patients treated with methotrexate.

1986 • 25 citations

Pneumococcal Vaccine in Rheumatoid Arthritis

1996 • 25 citations

The Risk of Cancer in Rheumatoid Patients in Japan

1995 • 24 citations

Immunosuppressive effects of (2R,5R)-6-heptyne-2,5-diamine an inhibitor of polyamine synthesis: I. Effects on mitogen-induced immunoglobulin production in human cultured lymphocytes.

1988 • 19 citations

Cancer in Transplantation: Prevention and Treatment

1996 • 16 citations

Genetics of HLA associated disease: ankylosing spondylitis.

1983 • 15 citations

Risk of malignancies in patients treated with Sandimmun® for autoimmune diseases

1996 • 7 citations

Long-term blood pressure changes in renal homotransplantation

1978 • 7 citations

Deleted Work

1955 • 0 citations