Mechanisms of plasma membrane protein degradation: recycling proteins are degraded more rapidly than those confined to the cell surface.

PLAQUE FORMATION AND ISOLATION OF PURE LINES WITH POLIOMYELITIS VIRUSES

1954 • 3,832 citations

Receptor-Mediated Endocytosis: Concepts Emerging from the LDL Receptor System

1985 • 1,585 citations

NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor.

1990 • 944 citations

Monensin interrupts the recycling of low density lipoprotein receptors in human fibroblasts

1981 • 593 citations

Characterization of the early endosome and putative endocytic carrier vesicles in vivo and with an assay of vesicle fusion in vitro.

1989 • 588 citations

Transferrin receptor internalization sequence YXRF implicates a tight turn as the structural recognition motif for endocytosis

1990 • 508 citations

Low temperature selectively inhibits fusion between pinocytic vesicles and lysosomes during heterophagy of 125I-asialofetuin by the perfused rat liver.

1980 • 451 citations

Kinetics of internalization and recycling of the asialoglycoprotein receptor in a hepatoma cell line.

1982 • 357 citations

Integral and peripheral protein composition of the apical and basolateral membrane domains in MDCK cells

1989 • 231 citations

ATP is required for receptor-mediated endocytosis in intact cells.

1990 • 206 citations

Temperature dependence of endocytosis mediated by the asialoglycoprotein receptor in isolated rat hepatocytes. Evidence for two potentially rate-limiting steps.

1981 • 187 citations

Biosynthesis and turnover of the mannose 6-phosphate receptor in cultured Chinese hamster ovary cells.

1983 • 169 citations

[54] High resolution one- and two-dimensional electrophoretic analysis of mitochondrial membrane polypeptides

1979 • 122 citations

Cation-dependent mannose 6-phosphate receptor contains two internalization signals in its cytoplasmic domain.

1990 • 121 citations

Intracellular pools of transferrin receptors result from constitutive internalization of unoccupied receptors.

1986 • 94 citations

A new method for detecting endocytosed proteins.

1988 • 79 citations

Turnover of plasma membrane glycoproteins and glycolipids of hepatoma tissue culture cells.

1978 • 78 citations

Mechanisms of membrane protein turnover

1990 • 73 citations

Turnover of plasma membrane proteins in rat hepatoma cells and primary cultures of rat hepatocytes.

1985 • 63 citations

Unusual forms of low density lipoprotein receptors in hamster cell mutants with defects in the receptor structural gene.

1986 • 58 citations

[3H]biotin-labeled proteins in cultured human skin fibroblasts from patients with pyruvate carboxylase deficiency.

1983 • 56 citations

Effects of temperature, pH elevators, and energy production inhibitors on horseradish peroxidase transport through endocytic vesicles

1987 • 44 citations

A one-step technique for the subcellular fractionation of total cell homogenates

1986 • 28 citations

Metabolic behavior of cell surface biotinylated proteins

1989 • 27 citations

Dissection of membrane protein degradation mechanisms by reversible inhibitors.

1988 • 20 citations

Novel feature of metabolism of low density lipoprotein receptor in a mouse macrophage-like cell line, J774.1.

1988 • 18 citations

Low-density-lipoprotein receptors in human fibroblasts are not degraded in lysosomes

1989 • 14 citations

Compartmentation and turnover of the low density lipoprotein receptor in skin fibroblasts.

1990 • 13 citations

Turnover and compartmentation of gp70p15 E in ψ2 cells

1989 • 4 citations