Isolation of the microtubule-vesicle motor kinesin from rat liver: Selective inhibition by cholestatic bile acids

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

[10] Assay of inorganic phosphate, total phosphate and phosphatases

1966 • 3,302 citations

Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility

1985 • 1,930 citations

In-gel digestion of proteins for internal sequence analysis after one- or two-dimensional gel electrophoresis

1992 • 1,259 citations

A Multicenter, Controlled Trial of Ursodiol for the Treatment of Primary Biliary Cirrhosis

1991 • 727 citations

Hepatology. A Textbook of Liver Disease

1990 • 638 citations

MAP 1C is a microtubule-activated ATPase which translocates microtubules in vitro and has dynein-like properties.

1987 • 563 citations

Organelle, bead, and microtubule translocations promoted by soluble factors from the squid giant axon

1985 • 346 citations

[28] Isolation of Chlamydomonas flagella and flagellar axonemes

1986 • 338 citations

Kinesin family in murine central nervous system.

1992 • 310 citations

Colchicine inhibition of plasma protein release from rat hepatocytes.

1975 • 300 citations

Influence of Hydroxylation and Conjugation of Bile Salts on Their Membrane-Damaging Properties-Studies on Isolated Hepatocytes and Lipid Membrane Vesicles

1984 • 290 citations

Ursodeoxycholate reduces hepatotoxicity of bile salts in primary human hepatocytes

1990 • 251 citations

Tubulin domains probed by limited proteolysis and subunit-specific antibodies

1985 • 224 citations

Conjugates of ursodeoxycholate protect against cholestasis and hepatocellular necrosis caused by more hydrophobic bile salts

1991 • 221 citations

Bovine brain kinesin is a microtubule-activated ATPase.

1986 • 215 citations

MOTOR PROTEINS OF CYTOPLASMIC MICROTUBULES

1990 • 196 citations

Cloning and expression of a human kinesin heavy chain gene: interaction of the COOH-terminal domain with cytoplasmic microtubules in transfected CV-1 cells

1992 • 193 citations

Hepatic processing of transforming growth factor beta in the rat. Uptake, metabolism, and biliary excretion.

1987 • 184 citations

The distribution, abundance and subcellular localization of kinesin.

1989 • 179 citations

Tauroursodeoxycholic acid stimulates hepatocellular exocytosis and mobilizes extracellular Ca++ mechanisms defective in cholestasis.

1993 • 164 citations

Characterization of the microtubule movement produced by sea urchin egg kinesin.

1987 • 153 citations

Characterization of the microtubule-activated ATPase of brain cytoplasmic dynein (MAP 1C).

1988 • 142 citations

Mechanism of secretion of biliary lipids: Role of a microtubular system in hepatocellular transport of biliary lipids in the rat

1978 • 137 citations

Hepatic Transport and Bile Secretion : Physiology and Pathophysiology

1992 • 136 citations

One motor, many tails: An expanding repertoire of force-generating enzymes

1990 • 134 citations

Purified kinesin promotes vesicle motility and induces active sliding between microtubules in vitro.

1991 • 124 citations

Effects of tauroursodeoxycholic acid on cytosolic Ca2+ signals in isolated rat hepatocytes

1993 • 121 citations

Evidence for a Role of the Microtubular System in the Secretion of Newly Synthesized Albumin and Other Proteins by the Liver

1974 • 117 citations

Transport of sodium, chloride, and taurocholate by cultured rat hepatocytes

1981 • 116 citations

Hepatic Transport and Bile Secretion: Physiology and Pathophysiology

1994 • 111 citations

Correlation between the ATPase and microtubule translocating activities of sea urchin egg kinesin

1987 • 110 citations

Calmodulin binding to and cAMP-dependent phosphorylation of kinesin light chains modulate kinesin ATPase activity

1993 • 106 citations

Isolation of a 45-kDa Fragment from the Kinesin Heavy Chain with Enhanced ATPase and Microtubule-binding Activities

1989 • 96 citations

Preparation of microtubules from rat liver and testis: Cytoplasmic dynein is a major microtubule associated protein

1989 • 93 citations

Copurification of kinesin polypeptides with microtubule‐stimulated Mg‐ATPase activity and kinetic analysis of enzymatic properties

1989 • 90 citations

Taurocholate stimulates transcytotic vesicular pathways labeled by horseradish peroxidase in the isolated perfused rat liver

1990 • 88 citations

Motor proteins for cytoplasmic microtubules

1992 • 87 citations

Morphometric Analysis of Rat Hepatocytes After Total Biliary Obstruction

1976 • 87 citations

Association of kinesin with the Golgi apparatus in rat hepatocytes

1994 • 83 citations

Hepatocyte Handling of Immunoglobulin a in the Rat: The Role of Microtubules

1983 • 79 citations

Tubulovesicular Transcytotic Pathway in Isolated Rat Hepatocyte Couplets in Culture

1988 • 74 citations

Effects of cytochalasin D and colchicine on the uptake, translocation, and biliary secretion of horseradish peroxidase and [14C]sodium taurocholate in the rat

1983 • 66 citations

Ursodeoxycholate mobilizes intracellular Ca2+ and activates phosphorylase a in isolated hepatocytes

1993 • 54 citations

Effect of colchicine on the transfer of IgA across hepatocytes into bile in isolated perfused rat livers

1980 • 50 citations

In vitro effect of bile salts on rat liver plasma membrane, lipid fluidity, and ATPase activity

1981 • 48 citations

Transcytotic vesicular carriers for polymeric iga receptors accumulate in rat hepatocytes after bile duct ligation

1991 • 47 citations

Microtubule motors: many new models off the assembly line

1992 • 44 citations

Demonstration of a Transcellular Vesicle Pathway for Biliary Excretion of Inulin in Rat Liver

1986 • 36 citations

Different effects of free and conjugated bile acids and their keto derivatives on (Na+, K+)-stimulated and Mg2+-ATPase of rat intestinal mucosa

1973 • 32 citations

MECHANISMS UNDERLYING THE PROLONGED DURATION OF ACTION OF MUSCLE RELAXANTS CAUSED BY EXTRAHEPATIC CHOLESTASIS

1981 • 24 citations

The influence of various bile salts and some cholephilic dyes on Na+, K+- and Mg2+-activated ATPase of rat liver in relation to cholestatic effects

1978 • 23 citations

Bile acid-dependent vesicular transport of lysosomal enzymes into bile in the rat

1993 • 23 citations

Bile salt related secretion of acid phosphatase in rat bile

1986 • 13 citations

Hepatic extraction of renin: Quantitation and characterization in the isolated perfused rat liver

1987 • 12 citations

Hepatic processing of recombinant human renin: mechanisms of uptake and degradation

1991 • 10 citations

Vesicle-dependent transport pathways in liver cells

1993 • 5 citations

An improved method for the purification of kinesin from bovine adrenal medulla

1992 • 5 citations