The Aging Gut: Physiology

Testosterone Replacement in Older Hypogonadal Men: A 12-Month Randomized Controlled Trial

1997 • 886 citations

Ghrelin controls hippocampal spine synapse density and memory performance

2006 • 806 citations

Cachexia: pathophysiology and clinical relevance1,2

2006 • 776 citations

Anorexia of aging: physiologic and pathologic

1997 • 751 citations

Oral Care Reduces Pneumonia in Older Patients in Nursing Homes

2002 • 741 citations

Age and disease related changes in intestinal bacterial populations assessed by cell culture, 16S rRNA abundance, and community cellular fatty acid profiles

2001 • 561 citations

Postprandial Hypotension: Epidemiology, Pathophysiology, and Clinical Management

1995 • 384 citations

Anorexia in the elderly

1988 • 359 citations

Catabolism of aging: is it an inflammatory process?

2003 • 298 citations

Effects of ageing on smell and taste

2006 • 292 citations

Studies of Intestinal Microflora

1967 • 289 citations

Evidence for the anorexia of aging: gastrointestinal transit and hunger in healthy elderly vs. young adults

1997 • 286 citations

[Drugs and the liver].

1970 • 278 citations

Anorexia, sarcopenia, and aging

2001 • 275 citations

Malnutrition in subacute care

2002 • 272 citations

Studies of Intestinal Microflora

1968 • 247 citations

Effects of age on concentrations of plasma cholecystokinin, glucagon-like peptide 1, and peptide YY and their relation to appetite and pyloric motility

1999 • 245 citations

The ascent of cholecystokinin (CCK) — From gut to brain

1982 • 241 citations

Liver Function and Phase I Drug Metabolism in the Elderly

2001 • 236 citations

Impaired Efficacy of Cough in Patients With Parkinson Disease

2003 • 223 citations

Invited Review: Aging and energy balance

2003 • 216 citations

Effect of Exogenous Cholecystokinin (CCK)-8 on Food Intake and Plasma CCK, Leptin, and Insulin Concentrations in Older and Young Adults: Evidence for Increased CCK Activity as a Cause of the Anorexia of Aging

2001 • 203 citations

Influence of normal aging on oral-pharyngeal and upper esophageal sphincter function during swallowing

1995 • 202 citations

Presbyesophagus: Esophageal Motility in Nonagenarians*

1964 • 192 citations

Evidence that nitric oxide modulates food intake in mice

1991 • 189 citations

Effects of ageing on gastrointestinal motor function

2004 • 184 citations

Relation between postprandial satiation and antral area in normal subjects

1997 • 184 citations

Cytokine-Related Aging Process

2004 • 181 citations

Physiological gastroesophageal reflux and esophageal motor activity studied with a new system for 24-hour recording and automated analysis

1989 • 163 citations

Capsaicin Troche for Swallowing Dysfunction in Older People

2005 • 160 citations

The anorexia of ageing.

2002 • 156 citations

Changes in Pancreatic Exocrine Secretion with Age: Pancreatic Exocrine Secretion Does Decrease in the Elderly

1991 • 155 citations

Pancreatic fibrosis associated with age and ductal papillary hyperplasia

2005 • 153 citations

Effect of age on gastric acid secretion and serum gastrin concentrations in healthy men and women

1991 • 151 citations

Ghrelin-induced feeding is dependent on nitric oxide

2003 • 148 citations

Neurodegeneration: a key factor in the ageing gut

2004 • 124 citations

Frailty

2006 • 122 citations

Effect of Aging on Anorectal and Pelvic Floor Functions in Females

2006 • 121 citations

Pharyngoglottal Closure Reflex: Characterization in Healthy Young, Elderly and Dysphagic Patients with Predeglutitive Aspiration

2002 • 119 citations

Influence of aging on oral-pharyngeal bolus transit and clearance during swallowing: scintigraphic study

1994 • 116 citations

The Patterns of Motility Are Maintained in the Human Small Intestine Throughout the Process of Aging

1992 • 113 citations

Frailty and the aging male

2005 • 107 citations

Taste Intensity Perception in Aging

1986 • 106 citations

Body composition and age in african-american and caucasian women: Relationship to plasma leptin levels

1997 • 106 citations

Effects of bombesin and gastrin-releasing peptide on memory processing

1988 • 105 citations

Leptin and neuropeptide Y (NPY) modulate nitric oxide synthase: further evidence for a role of nitric oxide in feeding

1999 • 105 citations

Rate of Gastric Emptying is a Determinant of Postprandial Hypotension in Non-Insulin-Dependent Diabetes Mellitus

1998 • 104 citations

Effect of Small Intestinal Nutrient Infusion on Appetite, Gastrointestinal Hormone Release, and Gastric Myoelectrical Activity in Young and Older Men

2001 • 101 citations

IV. Clinical and physiological aspects of gastrointestinal motility and aging

2002 • 101 citations

Correlation Between Serum Alanine Aminotransferase Activity and Age: An Inverted U Curve Pattern

2005 • 100 citations

Pancreas and Aging: A Study Using Ultrasonography

2000 • 97 citations

Effect of Aging on the Adult Extrahepatic Bile Duct

2003 • 93 citations

Evidence for a physiological role for CCK in the regulation of food intake in mice

1989 • 93 citations

Evaluation of the Effect of Age on Functioning Hepatocyte Mass and Liver Blood Flow Using Liver Scintigraphy in Preoperative Estimations for Surgical Patients: Comparison with CT Volumetry

2002 • 90 citations

Reduction of risk of pneumonia associated with use of angiotensin I converting enzyme inhibitors in elderly inpatients

1999 • 89 citations

Acarbose attenuates the hypotensive response to sucrose and slows gastric emptying in the elderly

2005 • 84 citations

Bolus Location at the Initiation of the Pharyngeal Stage of Swallowing in Healthy Older Adults

2005 • 84 citations

LIVER DISEASE IN THE ELDERLY

2001 • 75 citations

Effect of gastrointestinal peptides on ingestion in old and young mice

1988 • 75 citations

Office Management of Weight Loss in Older Persons

2006 • 73 citations

Postprandial hypotension in response to duodenal glucose delivery in healthy older subjects

2002 • 73 citations

Transit Time Changes with Age in the Gastrointestinal Tract of the Rat

1976 • 73 citations

Intraindividual Reproducibility of Postprandial and Orthostatic Blood Pressure Changes in Older Nursing‐Home Patients: Relationship with Chronic Use of Cardiovascular Medications

1996 • 72 citations

Effect of age and bolus variables on the coordination of the glottis and upper esophageal sphincter during swallowing.

1993 • 72 citations

An Overview of Diabetes Mellitus in Older Persons

1999 • 69 citations

Inhibition of feeding by a nitric oxide synthase inhibitor: effects of aging

1996 • 68 citations

The Effect of Aging on the Relationship between the Cytochrome P450 2C19 Genotype and Omeprazole Pharmacokinetics

2005 • 66 citations

Age-related changes in colonic function in rats

1984 • 63 citations

Regional Taste Sensitivity to NaCl: Relationship to Subject Age, Tongue Locus and Area of Stimulation

1995 • 62 citations

Effect of aging on bolus kinematics during the pharyngeal phase of swallowing

2006 • 60 citations

Effects of nitroglycerin on liquid gastric emptying and antropyloroduodenal motility

1998 • 55 citations

Fecal incontinence in the elderly patient

2003 • 53 citations

Age-associated decreases in prostaglandin contents in human gastric mucosa

1992 • 48 citations

Deletion allele of the angiotensin-converting enzyme gene as a risk factor for pneumonia in elderly patients

2002 • 47 citations

Does the Liver Ever Age? Results of Liver Transplantation With Donors Above 80 Years of Age

2005 • 47 citations

Diabetes mellitus in older men

2006 • 45 citations

Orexin-A-induced feeding is dependent on nitric oxide

2005 • 44 citations

Cholecystokinin receptors mediate enhanced memory retention produced by feeding and gastrointestinal peptides

1989 • 43 citations

Effects of drink volume and glucose load on gastric emptying and postprandial blood pressure in healthy older subjects

2005 • 43 citations

Relationship of age and calcitonin gene-related peptide to postprandial hypotension

1996 • 43 citations

Amylin

1992 • 41 citations

Smooth muscle inclusion bodies in slow transit constipation

2001 • 40 citations

Drugs and the liver. Part III: Ageing of the liver and the metabolism of drugs

1992 • 39 citations

Effects of amylin on appetite regulation and memory

1995 • 36 citations

Role of intestinal function in cachexia

2006 • 32 citations

Cleavage of Peptide Bonds by Angiotensin I Converting Enzyme

1987 • 28 citations

Postprandial Hypotension - Novel Insights into Pathophysiology and Therapeutic Implications

2006 • 26 citations

Age-related changes in amylin secretion

1996 • 25 citations

Influence of body mass index, sex and age on serum alanine aminotransferase (ALT) level in healthy blood donors.

1999 • 21 citations

A systematic analysis of polyglucosan bodies in the human gastrointestinal tract in health and disease

2003 • 20 citations

Taste and smell losses with age.

1991 • 20 citations

Role of nitric oxide mechanisms in gastric emptying of, and the blood pressure and glycemic responses to, oral glucose in healthy older subjects

2005 • 19 citations

Aging and Exocrine Pancreatic Function Evaluated by the Recently Standardized Secretin Test.

1991 • 18 citations

Effects of glyceryl trinitrate on the pyloric motor response to intraduodenal triglyceride infusion in humans

1996 • 17 citations

Evaluation of 16s rRNA and cellular fatty acid profiles as markers of human intestinal bacterial growth in the chemostat

2000 • 16 citations

Increase of Serum Pepsinogen I with Age in Females with Normal Gastric Mucosa but not in Males, Possibly Due to Increase in Acid-Pepsin Secreting Area

1991 • 7 citations

Aging and exocrine pancreatic function.

1989 • 3 citations

Deleted Work

1955 • 0 citations