Functional effects of expression of wolframin-antisense transcripts in BRIN-BD11 β-cells

β-Cell Deficit and Increased β-Cell Apoptosis in Humans With Type 2 Diabetes

2003 • 3,886 citations

Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats.

1999 • 1,207 citations

Neurodegeneration and diabetes: UK nationwide study of Wolfram (DIDMOAD) syndrome

1995 • 596 citations

A gene encoding a transmembrane protein is mutated in patients with diabetes mellitus and optic atrophy (Wolfram syndrome)

2000 • 525 citations

Diabetes insipidus, diabetes mellitus, optic atrophy and deafness (DIDMOAD) caused by mutations in a novel gene (wolframin) coding for a predicted transmembrane protein

1998 • 467 citations

Characterization of a Novel Glucose-Responsive Insulin-Secreting Cell Line, BRIN-BD11, Produced by Electrofusion

1996 • 345 citations

DIABETES MELLITUS AND SIMPLE OPTIC ATROPHY AMONG SIBLINGS: REPORT OF FOUR CASES

1938 • 338 citations

WFS1 (Wolfram syndrome 1) gene product: predominant subcellular localization to endoplasmic reticulum in cultured cells and neuronal expression in rat brain

2001 • 331 citations

beta-cell turnover: its assessment and implications.

2001 • 238 citations

Clinical and Molecular Genetic Analysis of 19 Wolfram Syndrome Kindreds Demonstrating a Wide Spectrum of Mutations in WFS1

1999 • 207 citations

A Novel Approach to Increase Human Islet Cell Mass While Preserving β-Cell Function

2002 • 204 citations

WFS1/wolframin mutations, Wolfram syndrome, and associated diseases

2001 • 173 citations

Genetically Programmed Selective Islet β-Cell Loss in Diabetic Subjects With Wolfram's Syndrome

1989 • 89 citations

WFS1 mutations in Spanish patients with diabetes mellitus and deafness

2002 • 36 citations

Expression of α2- and β-adrenoceptor subtypes in human islets of Langerhans

1996 • 33 citations

Mitochondrial diabetes, DIDMOAD and other inherited diabetes syndromes

2001 • 33 citations

Reflexions on a newly discovered diabetogenic gene, wolframin (WFS1)

1999 • 12 citations