A gene encoding a transmembrane protein is mutated in patients with diabetes mellitus and optic atrophy (Wolfram syndrome)

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Parametric and nonparametric linkage analysis: a unified multipoint approach.

1996 • 2,905 citations

A genome–wide search for human non–insulin–dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2

1996 • 601 citations

Diabetes Mellitus: Theory and Practice.

1971 • 559 citations

DIABETES MELLITUS AND SIMPLE OPTIC ATROPHY AMONG SIBLINGS: REPORT OF FOUR CASES

1938 • 338 citations

Autosomal recessive Wolfram syndrome associated with an 8.5-kb mtDNA single deletion.

1996 • 84 citations

Heterozygote and mutation detection by direct automated fluorescent DNA sequencing using a mutant Taq DNA polymerase.

1996 • 76 citations

Linkage of Wolfram syndrome to chromosome 4p16.1 and evidence for heterogeneity.

1996 • 71 citations

Otologic findings of DIDMOAD syndrome.

1991 • 29 citations

[Three sisters suffering from Wolfram (DIDMOAD) syndrome].

1987 • 1 citations

Deleted Work

1955 • 0 citations