Platelet α-adrenoceptors in heroin addicts during withdrawal and after treatment with clonidine

An Algorithm for Least-Squares Estimation of Nonlinear Parameters

1963 • 29,357 citations

Presynaptic regulation of the release of catecholamines.

1980 • 1,483 citations

Tolerance of locus coeruleus neurones to morphine and suppression of withdrawal response by clonidine

1978 • 794 citations

CLONIDINE BLOCKS ACUTE OPIATE-WITHDRAWAL SYMPTOMS

1978 • 705 citations

Presynaptic Receptors

1981 • 599 citations

THALIDOMIDE AND LIMB DEFORMITIES

1962 • 461 citations

The Human Platelet

1977 • 392 citations

Radioligand Binding Studies of Adrenergic Receptors: New Insights into Molecular and Physiological Regulation

1980 • 313 citations

Effects of clonidine on morphine withdrawal signs in the rat

1975 • 177 citations

Hypersensitivity to noradrenaline in cortex after chronic morphine: relevance to tolerance and dependence

1978 • 128 citations

α2-adrenoreceptors on human platelets: Selective labelling by [3H]clonidine and [3H]yohimbine and competetive inhibition by antidepressant drugs

1981 • 117 citations

The effects of alpha adrenergic agents on human platelet aggregation.

1979 • 112 citations

INTERACTION OF SELECTIVE α‐ADRENOCEPTOR AGONISTS AND ANTAGONISTS WITH HUMAN AND RABBIT BLOOD PLATELETS

1980 • 107 citations

Chronic morphine administration increases the apparent number of α2-adrenergic receptors in rat brain

1981 • 77 citations

New aspects of the pharmacokinetics and pharmacodynamics of clonidine in man

1983 • 72 citations

Alpha 2-adrenergic receptors in neuroblastoma x glioma hybrid cells. Characterization with agonist and antagonist radioligands and relationship to adenylate cyclase.

1982 • 69 citations

Effects of α₂‐adrenoceptor agonists and of related compounds on aggregation of, and on adenylate cyclase activity in, human platelets

1984 • 62 citations

Naltrexone precipitated opiate withdrawal in methadone addicted human subjects: Evidence for noradrenergic hyperactivity

1984 • 60 citations

Platelet alpha2 adrenoreceptors in chronic congestive heart failure

1983 • 48 citations

Brain catecholamine metabolites and behavior in morphine withdrawal

1982 • 42 citations

Alteration in β-adrenergic receptor binding in brain, lung and heart during morphine and alcohol dependence and withdrawal

1981 • 40 citations

In vitro and in vivo down-regulation of human platelet? 2-adrenoceptors by clonidine

1982 • 37 citations

Cardiovascular effects of breathing 95 percent oxygen in children with congenital heart disease

1983 • 30 citations

Chronic opiate treatment does not modify α2-adrenergic receptors in rat cerebral cortex, kidney and in the neurotumor cell line NCB20

1983 • 18 citations

Changes in alpha2 adrenoreceptors in various areas of the rat brain after long-term administration of “mu” and “kappa” opiate agonists

1983 • 16 citations

Excretion of Catecholamine Metabolites During Methadone Maintenance and Withdrawal

1983 • 9 citations

Effect of acute methadone withdrawal on prostaglandin E-stimulated 3H-cyclic adenosine monophosphate accumulation in human platelets

1980 • 9 citations

Morphine dependence and withdrawal without alterations in cerebral β-adrenergic receptor density

1984 • 8 citations

Heroin addicts have increased platelet α2-adrenoceptor densities which correlate with the severity of the abstinence syndrome

1984 • 6 citations