Modulation of cardiac sodium channel gating by lysophosphatidylcholine

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

The increase in bilayer fluidity of rat liver plasma membranes achieved by the local anesthetic benzyl alcohol affects the activity of intrinsic membrane enzymes.

1980 • 272 citations

Slow currents through single sodium channels of the adult rat heart.

1985 • 242 citations

Two modes of gating during late Na+ channel currents in frog sartorius muscle.

1986 • 182 citations

Statistical analysis of single sodium channels. Effects of N-bromoacetamide

1984 • 165 citations

Potential arrhythmogenic electrophysiological derangements in canine Purkinje fibers induced by lysophosphoglycerides.

1979 • 159 citations

Electrophysiological effects of amphiphiles on canine purkinje fibers. Implications for dysrhythmia secondary to ischemia.

1981 • 136 citations

The effects of lysophosphatidylcholine, a toxic metabolite of ischemia, on the components of cardiac excitability in sheep Purkinje fibers.

1981 • 120 citations

Oxygen requirements, morphology, cell coat and membrane permeability of calcium-tolerant myocytes from hearts of adult rats

1981 • 107 citations

On the mechanism of lysophosphatidylcholine-induced depolarization of cat ventricular myocardium.

1983 • 104 citations

Modulation of canine myocardial sarcolemmal membrane fluidity by amphiphilic compounds.

1984 • 100 citations

Modal gating behavior of cardiac sodium channels in cell-free membrane patches

1988 • 96 citations

Arrhythmogenic amphiphilic lipids and the myocardial cell membrane

1982 • 85 citations

Effects of lysophosphatidylcholine on resting potassium conductance of isolated guinea pig ventricular cells

1986 • 79 citations

Induction of delayed afterdepolarizations and triggered activity in canine Purkinje fibers by lysophosphoglycerides.

1986 • 76 citations

Properties of normal and non-inactivating single cardiac Na ⁺ channels

1987 • 52 citations

Opentime heterogeneity during bursting of sodium channels in frog skeletal muscle

1986 • 49 citations

Ischemic poison lysophosphatidylcholine modifies heart sodium channels gating inducing long-lasting bursts of openings

1989 • 48 citations

Pathophysiologic concentrations of lysophosphoglycerides quantified by electron microscopic autoradiography.

1984 • 37 citations

Conduction of the impulse in the ischemic myocardium — implications for malignant ventricular arrhythmias

1987 • 35 citations

Single channel sodium current in rat cardiomyocytes: use-dependent block by ethacizin.

1989 • 8 citations