Properties of normal and non-inactivating single cardiac Na ⁺ channels

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Inactivation of the sodium channel. I. Sodium current experiments.

1977 • 1,509 citations

Fitting and Statistical Analysis of Single-Channel Records

1983 • 1,098 citations

Sodium and calcium channels in bovine chromaffin cells

1982 • 983 citations

A reinterpretation of mammalian sodium channel gating based on single channel recording

1983 • 675 citations

Conductance properties of single inwardly rectifying potassium channels in ventricular cells from guinea‐pig heart.

1984 • 560 citations

The Principles of the Stochastic Interpretation of Ion-Channel Mechanisms

1995 • 549 citations

The steady state TTX-sensitive (?window?) sodium current in cardiac Purkinje fibres

1979 • 468 citations

Single Na+ channel currents observed in cultured rat muscle cells

1980 • 452 citations

Ionic selectivity, saturation, and block in sodium channels. A four-barrier model.

1975 • 400 citations

Multiple conductance states of single acetylcholine receptor channels in embryonic muscle cells

1981 • 327 citations

Statistical properties of single sodium channels.

1984 • 280 citations

Slow currents through single sodium channels of the adult rat heart.

1985 • 242 citations

Effect of tetrodotoxin on action potentials of the conducting system in the dog heart

1979 • 241 citations

Pacemaker activity and mitosis in cultures of newborn rat heart ventricle cells

1966 • 240 citations

Cardiac Na currents and the inactivating, reopening, and waiting properties of single cardiac Na channels.

1985 • 239 citations

Heart cells in culture: A simple method for increasing the proportion of myoblasts

1971 • 229 citations

The charge carried by single‐channel currents of rat cultured muscle cells in the presence of local anaesthetics.

1983 • 211 citations

Sodium channels in cultured cardiac cells.

1983 • 173 citations

Decreased rate of sodium conductance inactivation in the node of Ranvier induced by a polypeptide toxin from sea anemone

1976 • 171 citations

The Principles of the Stochastic Interpretation of Ion-Channel Mechanisms

1983 • 167 citations

Statistical analysis of single sodium channels. Effects of N-bromoacetamide

1984 • 165 citations

Destruction of the sodium conductance inactivation by a specific protease in perfused nerve fibres from Loligo.

1976 • 155 citations

Removal of sodium channel inactivation in squid giant axons by n-bromoacetamide.

1978 • 149 citations

Sodium current in single heart muscle cells

1979 • 146 citations

Slow inactivation of the sodium current in rabbit cardiac Purkinje fibres

1987 • 140 citations

Modification of single Na+ channels by batrachotoxin.

1982 • 137 citations

The initial inward current in spherical clusters of chick embryonic heart cells.

1980 • 123 citations

Slow inactivation of currents in cardiac Purkinje fibres

1968 • 115 citations

Evidence for two transient sodium currents in the frog node of Ranvier.

1985 • 109 citations

Sodium channels in rabbit cardiac Purkinje fibres

1979 • 100 citations

Voltage and time dependence of excitatory sodium current in cooled sheep Purkinje fibres

1970 • 95 citations

Single Na channels in mouse neuroblastoma cell membrane

1983 • 94 citations

Low intracellular pH and chemical agents slow inactivation gating in sodium channels of muscle

1980 • 93 citations

Modification of single cardiac Na+ channels by DPI 201-106

1986 • 90 citations

Inactivation of the sodium permeability in squid giant nerve fibres

1979 • 88 citations

Sodium currents in voltage clamped nerve fiber of frog under the combined action of batrachotoxin and procaine

1975 • 83 citations

Sodium Conductance Activation without Inactivation in Pronase-perfused Axons

1971 • 79 citations

Kinetics of Channel Gating in Excitable Membranes

1976 • 68 citations

Two Types of Voltage Dependent Na Channels Suggested by Differential Sensitivity of Single Channels to Tetrodotoxin

1984 • 41 citations

Chemical modification of crayfish axons by protein crosslinking aldehydes

1969 • 40 citations

Unitary sodium channels in isolated cardiac myocytes of rabbit.

1983 • 34 citations