Ro 40-7592: inhibition of COMT in rat brain and extracerebral tissues

Neurochemical profile of moclobemide, a short-acting and reversible inhibitor of monoamine oxidase type A.

1989 • 195 citations

Catechol‐O‐methyltransferase‐Inhibiting Pyrocatechol Derivatives: Synthesis and Structure‐Activity Studies

1989 • 114 citations

Ro 40-7592, a novel, very potent, and orally active inhibitor of catechol-O-methyltransferase: a pharmacological study in rats.

1990 • 87 citations

Inhibition of Decarboxylase and Levels of Dopa and 3-O-Methyldopa: A Comparative Study of Benserazide versus Carbidopa in Rodents and of Madopar Standard versus Madopar HBS in Volunteers

1987 • 47 citations

New Therapeutic Strategies in Parkinson’s Disease: Inhibition of MAO-B by Ro 19-6327 and of COMT by Ro 40-7592

1991 • 27 citations

Simple automated high-performance liquid chromatographic column-switching technique for the measurement of dopa and 3-O-methyldopa in plasma

1990 • 23 citations

Levodopa and 3-O-Methyldopa Plasma Levels in Parkinsonian Patients with Stable and Fluctuating Motor Response

1989 • 13 citations

‘On-Off’ Phenomenon: Description, Incidence and Management

1987 • 2 citations