A Role for IFN‐γ and NK Cells in Immune Responses to T Cell‐Regulated Antigens Types 1 and 2

Characterization of the Murine Antigenic Determinant, Designated L3T4a, Recognized by Monoclonal Antibody GK 1.5: Expression of L3T4a by Functional T Cell Clones Appears to Correlate Primarily with Class II MHC Antigen‐Reactivity

1983 • 1,040 citations

Therapy with monoclonal antibodies by elimination of T-cell subsets in vivo

1984 • 884 citations

Production of a monoclonal antibody to and molecular characterization of B-cell stimulatory factor-1

1985 • 749 citations

A T cell activity that enhances polyclonal IgE production and its inhibition by interferon-gamma.

1986 • 727 citations

Activated B cells express receptors for, and proliferate in response to, pure interleukin 2.

1984 • 361 citations

GENETIC CONTROL OF THE ANTIBODY RESPONSE TO TYPE III PNEUMOCOCCAL POLYSACCHARIDE IN MICE

1972 • 349 citations

Capacity of human large granular lymphocytes (LGL) to produce multiple lymphokines: interleukin 2, interferon, and colony stimulating factor.

1983 • 294 citations

γ-Interferon is one of several direct B cell-maturing lymphokines

1984 • 237 citations

Role of γ-interferon in antibody-producing responses

1984 • 203 citations

X-linked B-lymphocyte immune defect in CBA/N mice. II. Studies of the mechanisms underlying the immune defect.

1975 • 200 citations

Absence of the Lyt-2-,L3T4+ lineage of T cells in mice treated neonatally with anti-I-A correlates with absence of intrathymic I-A-bearing antigen-presenting cell function.

1985 • 191 citations

Identification of a B-cell surface structure involved in antigen-dependent triggering: absence of this structure on B cells from CBA/N mutant mice.

1977 • 178 citations

The Ontogeny of Thymic Independent Antibody Responses in Vitro in Normal Mice and Mice with an X-Linked B Cell Defect

1977 • 171 citations

Interferon-gamma suppresses B cell stimulation factor (BSF-1) induction of class II MHC determinants on B cells.

1986 • 138 citations

T-independent responses in B cell-defective CBA/N mice toBrucella abortus and to trinitrophenyl (TNP) conjugates ofBrucella abortus

1978 • 129 citations

Regulation of Growth and Proliferation in B Cell Subpopulations

1982 • 112 citations

Both interleukin 2 and a second T cell-derived factor in EL-4 supernatant have activity as differentiation factors in IgM synthesis.

1984 • 106 citations

Separable helper factors support B cell proliferation and maturation to Ig secretion.

1982 • 85 citations

B cell helper factors. II. Synergy among three helper factors in the response of T cell- and macrophage-depleted B cells.

1982 • 78 citations

Recombinant interferon-gamma inhibits the B cell proliferative response stimulated by soluble but not by Sepharose-bound anti-immunoglobulin antibody.

1985 • 77 citations

Size-dependent B lymphocyte subpopulations: relationship of cell volume to surface phenotype, cell cycle, proliferative response, and requirements for antibody production to TNP-Ficoll and TNP-BA.

1984 • 74 citations

B cell activation. VII. Independent and synergistic effects of mobilized calcium and diacylglycerol on membrane potential and I-A expression.

1986 • 61 citations

B-lymphocyte responses to trinitrophenyl-conjugated Ficoll: requirement for T lymphocytes and Ia-bearing adherent cells.

1981 • 59 citations

T cell dependence and factor reconstitution of in vitro antibody responses to TNP-B. Abortus and TNP-Ficoll: restoration of depleted responses with chromatographed fractions of a T cell-derived factor.

1983 • 59 citations

A reappraisal of "T-independent" antigens. I. Effect of lymphokines on the response of single adult hapten-specific B lymphocytes.

1984 • 52 citations

Activation of antigen-enriched b cells. I. Purification and response to thymus-independent antigens.

1983 • 50 citations

Giardiasis in mice: studies on the characteristics of chronic infection in C3h/He mice.

1981 • 49 citations

Analysis of B Cell Activation Requirements with TNP-Conjugated Polyacrylamide Beads

1979 • 43 citations

Obligatory role of gamma interferon in T cell-replacing factor-dependent, antigen-specific murine B cell responses.

1985 • 43 citations

Affinity-purified interleukin 2 induces proliferation of large but not small B cells.

1985 • 41 citations

Regulation of the IgM and IgA anti-dextran B1355S response: synergy between IFN-gamma, BCGF II, and IL 2.

1985 • 37 citations

T cell control of the antibody response to the T-independent antigen, DAGG-Ficoll.

1982 • 36 citations

Altered idiotype response to phosphocholine in mice bearing an x-linked immune defect.

1981 • 27 citations

DBA/2Ha Mice as a Model of an X‐Linked Immunodeficiency which is Defective in the Expression of TRF‐Acceptor Site(s) on B Lymphocytes

1982 • 25 citations

Comparison of the calcium requirement for the induction and maintenance of B cell class II molecule expression and for B cell proliferation stimulated by mitogens and purified growth factors.

1987 • 23 citations

Neonatal suppression with anti-Ia antibody. I. Suppression of murine B lymphocyte development.

1982 • 23 citations

Characterization of B cell subpopulations by velocity sedimentation, surface la antigens and immune function

1977 • 22 citations

Regulation of B cell activation by prostaglandins: cell cycle-specific effects on activation by anti-immunoglobulin and 8-mercaptoguanosine.

1986 • 20 citations

Restoration of in vitro responsiveness of xid B cells to TNP-Ficoll by 8-mercaptoguanosine.

1986 • 18 citations

Leu-Leu-OMe sensitivity of human activated killer cells: delineation of a distinct class of cytotoxic T lymphocytes capable of lysing tumor targets.

1986 • 13 citations

Murine immunogenicity of N-substituted phosphatidylethanolamine derivatives in liposomes: response to the hapten phosphocholine.

1980 • 9 citations

T-Cell Replacing Factor Activity of Recombinant-Derived Interleukin-2 Requires Gamma-Interferon

1986 • 2 citations