Effect of SLCO1B1 genetic polymorphism on the pharmacokinetics of nateglinide

The Rising Global Burden of Diabetes and its Complications: Estimates and Projections to the Year 2010

1997 • 1,777 citations

Bile Salt Transporters: Molecular Characterization, Function, and Regulation

2003 • 946 citations

Polymorphisms of OATP-C (SLC21A6) and OAT3 (SLC22A8) genes: Consequences for pravastatin pharmacokinetics

2003 • 514 citations

The Rising Global Burden of Diabetes and its Complications: Estimates and Projections to the Year 2010

1997 • 496 citations

High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C, SLCO1B1)

2004 • 419 citations

Gemfibrozil and Its Glucuronide Inhibit the Organic Anion Transporting Polypeptide 2 (OATP2/OATP1B1:SLC21A6)-Mediated Hepatic Uptake and CYP2C8-Mediated Metabolism of Cerivastatin: Analysis of the Mechanism of the Clinically Relevant Drug-Drug Interaction between Cerivastatin and Gemfibrozil

2004 • 403 citations

Polymorphic organic anion transporting polypeptide 1B1 is a major determinant of repaglinide pharmacokinetics

2005 • 358 citations

CYP2C9 allelic variants: ethnic distribution and functional significance

2002 • 333 citations

Evidence for inverse effects of OATP-C (SLC21A6) *5 and *1b haplotypes on pravastatin kinetics

2004 • 293 citations

Effects of gemfibrozil, itraconazole, and their combination on the pharmacokinetics and pharmacodynamics of repaglinide: potentially hazardous interaction between gemfibrozil and repaglinide

2003 • 276 citations

Gemfibrozil considerably increases the plasma concentrations of rosiglitazone

2003 • 188 citations

Gemfibrozil Inhibits CYP2C8-Mediated Cerivastatin Metabolism in Human Liver Microsomes

2002 • 186 citations

Clinical Pharmacokinetics of Nateglinide

2004 • 100 citations

Pharmacokinetics and metabolism of nateglinide in humans.

2001 • 87 citations

Meglitinide Analogues in the Treatment of Type 2 Diabetes Mellitus

2000 • 87 citations

Influence of CYP2C9 and CYP2D6 Polymorphisms on the Pharmacokinetics of Nateglinide in Genotyped Healthy Volunteers

2004 • 79 citations

A new hypoglycemic agent, A-4166, inhibits ATP-sensitive potassium channels in rat pancreatic beta-cells

1995 • 52 citations

A novel D-phenylalanine-derivative hypoglycemic agent A-4166 increases cytosolic free Ca2+ in rat pancreatic beta-cells by stimulating Ca2+ influx.

1994 • 48 citations

Effect of gemfibrozil on the pharmacokinetics and pharmacodynamics of racemic warfarin in healthy subjects

2005 • 44 citations

Coadministration of gemfibrozil and itraconazole has only a minor effect on the pharmacokinetics of the CYP2C9 and CYP3A4 substrate nateglinide

2005 • 41 citations

A novel D-phenylalanine-derivative hypoglycemic agent A-4166 increases cytosolic free Ca2+ in rat pancreatic beta-cells by stimulating Ca2+ influx

1994 • 17 citations