Trypanosoma cruzi trans-sialidase and cell invasion

A novel cell surface trans-sialidase of trypanosoma cruzi generates a stage-specific epitope required for invasion of mammalian cells

1991 • 420 citations

Human alternative complement pathway: membrane-associated sialic acid regulates the competition between B and beta1 H for cell-bound C3b.

1979 • 339 citations

Human Alternative Complement Pathway: Membrane-Associated Sialic Acid Regulates the Competition between B and β1H for Cell-Bound C3b

1979 • 257 citations

Stage-specific surface antigens expressed during the morphogenesis of vertebrate forms of Trypanosoma cruzi

1987 • 238 citations

A T. cruzi-secreted protein immunologically related to the complement component C9: Evidence for membrane pore-forming activity at low pH

1990 • 211 citations

A novel T. cruzi heparin-binding protein promotes fibroblast adhesion and penetration of engineered bacteria and trypanosomes into mammalian cells

1991 • 202 citations

Incorporation of sialic acid into Trypanosoma cruzi macromolecules. A proposal for a new metabolic route

1985 • 193 citations

A Developmentally Regulated Neuraminidase Activity in Trypanosoma cruzi

1983 • 181 citations

Identification of a Trypanosoma cruzi antigen that is shed during the acute phase of Chagas' disease

1989 • 181 citations

Conserved sequences in bacterial and viral sialidases

1989 • 181 citations

Metacyclic neutralizing effect of monoclonal antibody 10D8 directed to the 35- and 50-kilodalton surface glycoconjugates of Trypanosoma cruzi

1989 • 157 citations

Lectins of Distinct Specificity in Rhodnius prolixus Interact Selectively with Trypanosoma cruzi

1981 • 157 citations

Multiple Trypanosoma cruzi antigens containing tandemly repeated amino acid sequence motifs

1988 • 154 citations

Development and interactions of Trypanosoma cruzi within the insect vector

1991 • 153 citations

Desialylation of lysosomal membrane glycoproteins by Trypanosoma cruzi: a role for the surface neuraminidase in facilitating parasite entry into the host cell cytoplasm.

1992 • 135 citations

Trypanosoma cruzi trans-sialidase and neuraminidase activities can be mediated by the same enzymes.

1992 • 134 citations

The Trypanosoma cruzi neuraminidase contains sequences similar to bacterial neuraminidases, YWTD repeats of the low density lipoprotein receptor, and type III modules of fibronectin.

1991 • 131 citations

Substrate specificity of the Trypanosoma cruzi trans-sialidase

1992 • 127 citations

Identification of the gene(s) coding for the trans-sialidase of Trypanosoma cruzi.

1992 • 115 citations

Cloning of a major surface-antigen gene of Trypanosoma cruzi and identification of a nonapeptide repeat

1986 • 99 citations

The Occurrence ofN-Acetyl- andN-Glycoloylneuraminic Acid inTrypanosoma cruzi

1983 • 98 citations

A superfamily of trypanosoma cruzi surface antigens

1992 • 96 citations

Mammalian cell sialic acid enhances invasion by Trypanosoma cruzi

1993 • 93 citations

Direct sialic acid transfer from a protein donor to glycolipids of trypomastigote forms of Trypanosoma cruzi

1987 • 87 citations

Characterization of a novel trans-sialidase of Trypanosoma brucei procyclic trypomastigotes and identification of procyclin as the main sialic acid acceptor.

1993 • 86 citations

Attachment of Trypanosoma cruzi trypomastigotes to receptors at restricted cell surface domains

1991 • 84 citations

The 35/50 kDa surface antigen of Trypanosoma cruzi metacyclic trypomastigotes, an adhesion molecule involved in host cell invasion

1993 • 83 citations

The complete sequence of a shed acute-phase antigen of Trypanosoma cruzi

1991 • 83 citations

Only some members of a gene family in Trypanosoma cruzi encode proteins that express both trans-sialidase and neuraminidase activities.

1992 • 82 citations

SAPA/ trans ‐sialidase and cruzipain: two antigens from Trypanosoma cruzi contain immunodominant but enzymatically inactive domains

1992 • 76 citations

The major 85-kD surface antigen of the mammalian form of Trypanosoma cruzi is encoded by a large heterogeneous family of simultaneously expressed genes.

1990 • 73 citations

Stage-specific expression and intracellular shedding of the cell surface trans-sialidase of Trypanosoma cruzi

1992 • 62 citations

Monoclonal antibodies against Trypanosoma cruzi neuraminidase reveal enzyme polymorphism, recognize a subset of trypomastigotes, and enhance infection in vitro.

1990 • 60 citations

The biology of Trypanosoma cruzi-macrophage interaction

1989 • 59 citations

Evidence for the participation of the Ssp-3 antigen in the invasion of nonphagocytic mammalian cells by Trypanosoma cruzi.

1992 • 55 citations

An 85-kilodalton surface antigen gene family of Trypanosoma cruzi encodes polypeptides homologous to bacterial neuraminidases

1991 • 54 citations

Nucleotide sequence and transcription of a trypomastigote surface antigen gene of Trypanosoma cruzi

1991 • 50 citations

Purification and characterization of a novel sialidase found in procyclic culture forms of Trypanosoma brucei

1992 • 47 citations

Stage-specific phospholipase C-mediated release of Trypanosoma cruzi neuraminidase

1991 • 42 citations

The effect of fetuin and other sialoglycoproteins on the in vitro penetration of Trypanosoma cruzi trypomastigotes into fibroblastic cells

1987 • 42 citations

High- and low-density lipoproteins enhance infection of Trypanosoma cruzi in vitro

1990 • 41 citations

Synanthropic trends in urban andextraurban taxocenoses of Sarcophaginae (Diptera) in three central european cities

1989 • 35 citations

Mapping of a B-cell epitope present in the neuraminidase of Trypanosoma cruzi

1992 • 20 citations

Immunocytochemical localization of neuraminidase in Trypanosoma cruzi

1990 • 19 citations

Differential expression of Trypanosoma cruzi neuraminidase in intra- and extracellular trypomastigotes

1991 • 18 citations