Mammalian cell sialic acid enhances invasion by Trypanosoma cruzi

The immobilized leukoagglutinin from the seeds of Maackia amurensis binds with high affinity to complex-type Asn-linked oligosaccharides containing terminal sialic acid-linked alpha-2,3 to penultimate galactose residues.

1988 • 449 citations

A novel cell surface trans-sialidase of trypanosoma cruzi generates a stage-specific epitope required for invasion of mammalian cells

1991 • 420 citations

Cell Biology of Trypanosoma cruzi

1984 • 321 citations

Translocation across golgi vesicle membranes: A CHO glycosylation mutant deficient in CMP-sialic acid transport

1984 • 266 citations

Stage-specific surface antigens expressed during the morphogenesis of vertebrate forms of Trypanosoma cruzi

1987 • 238 citations

A novel T. cruzi heparin-binding protein promotes fibroblast adhesion and penetration of engineered bacteria and trypanosomes into mammalian cells

1991 • 202 citations

[MORPHOLOGICAL VARIATIONS OBSERVED IN DIFFERENT STRAINS OF TRYPANOSOMA CRUZI].

1963 • 200 citations

Incorporation of sialic acid into Trypanosoma cruzi macromolecules. A proposal for a new metabolic route

1985 • 193 citations

Complementation between mutants of CHO cells resistant to a variety of plant lectins

1977 • 159 citations

Metacyclic neutralizing effect of monoclonal antibody 10D8 directed to the 35- and 50-kilodalton surface glycoconjugates of Trypanosoma cruzi

1989 • 157 citations

Attachment of Trypanosoma cruzi to mammalian cells requires parasite energy, and invasion can be independent of the target cell cytoskeleton

1991 • 141 citations

Trypanosoma cruzi trans-sialidase and neuraminidase activities can be mediated by the same enzymes.

1992 • 134 citations

The Trypanosoma cruzi neuraminidase contains sequences similar to bacterial neuraminidases, YWTD repeats of the low density lipoprotein receptor, and type III modules of fibronectin.

1991 • 131 citations

Trypanosoma cruzi Infection Inhibited by Peptides Modeled from a Fibronectin Cell Attachment Domain

1986 • 92 citations

Direct sialic acid transfer from a protein donor to glycolipids of trypomastigote forms of Trypanosoma cruzi

1987 • 87 citations

Trypanosoma cruzi: Interaction with Host Cells

1985 • 85 citations

Attachment of Trypanosoma cruzi trypomastigotes to receptors at restricted cell surface domains

1991 • 84 citations

The 35/50 kDa surface antigen of Trypanosoma cruzi metacyclic trypomastigotes, an adhesion molecule involved in host cell invasion

1993 • 83 citations

Only some members of a gene family in Trypanosoma cruzi encode proteins that express both trans-sialidase and neuraminidase activities.

1992 • 82 citations

Differential involvement of cell surface sialic acid residues in wheat germ agglutinin binding to parental and wheat germ agglutinin-resistant Chinese hamster ovary cells.

1980 • 80 citations

Qualitative and quantitative histochemical changes in the caecum and liver of turkeys infected withHistomonas meleagridis

1976 • 60 citations

Monoclonal antibodies against Trypanosoma cruzi neuraminidase reveal enzyme polymorphism, recognize a subset of trypomastigotes, and enhance infection in vitro.

1990 • 60 citations

Evidence for the participation of the Ssp-3 antigen in the invasion of nonphagocytic mammalian cells by Trypanosoma cruzi.

1992 • 55 citations

The N-linked carbohydrate chain of the 85-kilodalton glycoprotein from Trypanosoma cruzi trypomastigotes contains sialyl, fucosyl and galactosyl (α1–3)galactose units

1990 • 51 citations

Trypanosoma Species (American Trypanosomiasis, Chagas' Disease)

2015 • 50 citations

The effect of fetuin and other sialoglycoproteins on the in vitro penetration of Trypanosoma cruzi trypomastigotes into fibroblastic cells

1987 • 42 citations

High- and low-density lipoproteins enhance infection of Trypanosoma cruzi in vitro

1990 • 41 citations

Metacyclic Neutralizing Effect ofMonoclonal Antibody 1OD8 Directed tothe35-and50-Kilodalton Surface Glycoconjugates ofTrypanosoma cruzi

1989 • 3 citations