Expression and Regulation of Adhesion Molecules in Cardiac Cells by Cytokines

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm

1994 • 7,068 citations

Function and Activation of NF-kappaB in the Immune System

1994 • 4,698 citations

Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation

1995 • 4,589 citations

Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor

1987 • 3,057 citations

The stress-activated protein kinase subfamily of c-Jun kinases

1994 • 2,616 citations

Induction by IL 1 and interferon-gamma: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1).

1986 • 2,490 citations

The Regulation of AP-1 Activity by Mitogen-activated Protein Kinases

1995 • 2,441 citations

Pro-inflammatory Cytokines and Environmental Stress Cause p38 Mitogen-activated Protein Kinase Activation by Dual Phosphorylation on Tyrosine and Threonine

1995 • 2,238 citations

VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/Fibronectin binding site

1990 • 1,836 citations

Transcriptional regulation of endothelial cell adhesion molecules: NF‐κB and cytokine‐inducible enhancers

1995 • 1,715 citations

Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes

1989 • 1,715 citations

Overlapping patterns of activation of human endothelial cells by interleukin 1, tumor necrosis factor, and immune interferon.

1986 • 1,439 citations

Endothelial-Leukocyte Adhesion Molecules

1993 • 1,324 citations

Sounding the Alarm: Protein Kinase Cascades Activated by Stress and Inflammation

1996 • 1,099 citations

Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells.

1993 • 1,079 citations

Parallel signal processing among mammalian MAPKs

1995 • 1,015 citations

Inflammatory and immune responses are impaired in mice deficient in intercellular adhesion molecule 1.

1993 • 563 citations

Transcriptional Regulation of the Intercellular Adhesion Molecule-1 Gene by Inflammatory Cytokines in Human Endothelial Cells

1995 • 540 citations

Leukocytosis and resistance to septic shock in intercellular adhesion molecule 1-deficient mice.

1994 • 492 citations

Characterization of the promoter for vascular cell adhesion molecule-1 (VCAM-1).

1992 • 476 citations

Differentiation of rat myocytes in single cell cultures with and without proliferating nonmyocardial cells. Cross-striations, ultrastructure, and chronotropic response to isoproterenol.

1982 • 454 citations

The proteasome pathway is required for cytokine-induced endothelial-leukocyte adhesion molecule expression

1995 • 354 citations

Hypoxia-mediated induction of endothelial cell interleukin-1 alpha. An autocrine mechanism promoting expression of leukocyte adhesion molecules on the vessel surface.

1992 • 341 citations

Molecular determinants of reperfusion-induced leukocyte adhesion and vascular protein leakage.

1994 • 328 citations

Coronary endothelial and cardiac protective effects of a monoclonal antibody to intercellular adhesion molecule-1 in myocardial ischemia and reperfusion.

1992 • 296 citations

Hypoxic Stress Induces Cardiac Myocyte–Derived Interleukin-6

1995 • 291 citations

Inhibition of protein kinase C-alpha expression in human A549 cells by antisense oligonucleotides inhibits induction of intercellular adhesion molecule 1 (ICAM-1) mRNA by phorbol esters.

1994 • 289 citations

H2O2 and Tumor Necrosis Factor-α Activate Intercellular Adhesion Molecule 1 (ICAM-1) Gene Transcription through Distinct cis-Regulatory Elements within the ICAM-1 Promoter

1995 • 284 citations

Hypoxia increases production of interleukin-1 and tumor necrosis factor by human mononuclear cells

1991 • 262 citations

Therapeutic potential of inhibiting leukocyte rolling in ischemia/reperfusion.

1995 • 256 citations

Regional differences in constitutive and induced ICAM-1 expression in vivo

1995 • 254 citations

Regulation of intercellular adhesion molecule-1 (ICAM-1) in ischemic and reperfused canine myocardium.

1993 • 228 citations

Regulatory elements and transcription factors controlling basal and cytokine-induced expression of the gene encoding intercellular adhesion molecule 1.

1994 • 217 citations

Neutrophil adherence to isolated adult canine myocytes. Evidence for a CD18-dependent mechanism.

1990 • 217 citations

Induction and nuclear accumulation of fos and jun proto-oncogenes in hypoxic cardiac myocytes

1993 • 206 citations

Anoxia/reoxygenation-induced neutrophil adherence to cultured endothelial cells

1992 • 204 citations

Elevated cyclic AMP inhibits endothelial cell synthesis and expression of TNF-induced endothelial leukocyte adhesion molecule-1, and vascular cell adhesion molecule-1, but not intercellular adhesion molecule-1.

1993 • 192 citations

Adherence of neutrophils to canine cardiac myocytes in vitro is dependent on intercellular adhesion molecule-1.

1991 • 162 citations

Expression of intercellular adhesion molecule-1 in rat heart with ischemia/reperfusion and limitation of infarct size by treatment with antibodies against cell adhesion molecules.

1993 • 155 citations

A growth factor for cardiac myocytes is produced by cardiac nonmyocytes.

1991 • 151 citations

Hypoxia/reoxygenation stimulates endothelium to promote neutrophil adhesion

1992 • 123 citations

Effect of hypoxia on release of IL-1 and TNF by human alveolar macrophages.

1996 • 103 citations

Increased expression of ICAM-1 during reoxygenation in brain endothelial cells.

1994 • 85 citations

Molecular evidence for induction of intracellular adhesion molecule-1 in the viable border zone associated with ischemia-reperfusion injury of the dog heart.

1994 • 82 citations

Interleukin 1 and tumour necrosis factor activate the mitogen‐activated protein (MAP) kinase kinase in cultured cells

1993 • 73 citations

Chronic Hypoxia Modulates the Interleukin-1β–Stimulated Inducible Nitric Oxide Synthase Pathway in Cardiac Myocytes

1997 • 70 citations

Neutrophil Adherence to Rat Cardiac Myocyte by Proinflammatory Cytokines

1994 • 60 citations

Protection of ischemic/reperfused canine myocardium by CL18/6, a monoclonal antibody to adhesion molecule ICAM-1

1995 • 54 citations

Chronic Hypoxia Differentially Regulates α ₁ -Adrenergic Receptor Subtype mRNAs and Inhibits α ₁ -Adrenergic Receptor–Stimulated Cardiac Hypertrophy and Signaling

1995 • 51 citations

Expression of intercellular adhesion molecule-1 on rat cardiac myocytes by monocyte chemoattractant protein-1

1994 • 49 citations

Activation of protein kinase C is crucial in the regulation of ICAM-1 expression on endothelial cells by interferon-γ

1990 • 46 citations

Hypoxia and glucose independently regulate the beta-adrenergic receptor-adenylate cyclase system in cardiac myocytes.

1991 • 34 citations

Biphasic effect of camp‐elevating agents on ICAM‐1 expression stimulated by retinoic acid and interferonγ

1992 • 24 citations

Protease inhibitors: novel therapeutic application and development

1996 • 21 citations

Induction of mRNAs for ICAM‐1, VCAM‐1, and ELAM‐1 in cultured rat cardiac myocytes and myocardium in vivo

1997 • 17 citations

EXPRESSION OF VASCULAR CELL ADHESION MOLECULE-1 IN MURINE HEARTS WITH ACUTE MYOCARDITIS CAUSED BY COXSACKIEVIRUS B3

1996 • 17 citations