Maturational Regulation and Regional Induction of Cyclooxygenase-2 in Rat Brain: Implications for Alzheimer's Disease

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2

1995 • 2,308 citations

TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue

1991 • 1,814 citations

Limbic seizure and brain damage produced by kainic acid: Mechanisms and relevance to human temporal lobe epilepsy

1985 • 1,730 citations

Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease

1996 • 1,371 citations

Expression of a mitogen-inducible cyclooxygenase in brain neurons: Regulation by synaptic activity and glucocorticoids

1993 • 1,222 citations

Differentiation of newly born neurons and glia in the dentate gyrus of the adult rat

1993 • 1,215 citations

Clinical trial of indomethacin in Alzheimer's disease

1993 • 996 citations

Adult neurogenesis is regulated by adrenal steroids in the dentate gyrus

1994 • 986 citations

cDNA cloning and functional activity of a glucocorticoid-regulated inflammatory cyclooxygenase.

1992 • 838 citations

An autoradiographic study of the time of origin and the pattern of granule cell migration in the dentate gyrus of the rat

1975 • 725 citations

Widespread patterns of neuronal damage following systemic or intracerebral injections of kainic acid: A histological study

1980 • 700 citations

COX-2, a synaptically induced enzyme, is expressed by excitatory neurons at postsynaptic sites in rat cerebral cortex.

1996 • 597 citations

Inverse association of anti‐inflammatory treatments and Alzheimer's disease

1994 • 567 citations

Delayed onset of Alzheimer's disease with nonsteroidal anti-inflammatory and histamine H2 blocking drugs

1995 • 460 citations

Cloning Two Isoforms of Rat Cyclooxygenase: Differential Regulation of Their Expression

1993 • 457 citations

The mechanism of action of nonsteroidal antiinflammatory drugs.

1991 • 456 citations

Nonsteroidal anti-inflammatory drugs in Alzheimer's disease

1995 • 442 citations

Do nonsteroidal anti-inflammatory drugs decrease the risk for Alzheimer's disease?

1995 • 284 citations

p53 induction is associated with neuronal damage in the central nervous system.

1994 • 262 citations

Induction by lipopolysaccharide of cyclooxygenase-2 mRNA in rat brain; its possible role in the febrile response

1995 • 252 citations

Transcriptional regulation of the rat prostaglandin endoperoxide synthase 2 gene in granulosa cells. Evidence for the role of a cis-acting C/EBP beta promoter element.

1993 • 234 citations

Nonsteroidal antiinflammatory drugs cause apoptosis and induce cyclooxygenases in chicken embryo fibroblasts.

1995 • 210 citations

Cyclooxygenase‐2 Induction in Cerebral Cortex: An Intracellular Response to Synaptic Excitation

1996 • 201 citations

Role of prostaglandin D2 in the hypothermia of rats caused by bacterial lipopolysaccharide.

1982 • 177 citations

EXPRESSION OF CYCLOOXYGENASE-2 IN HUMAN AND AN ANIMAL MODEL OF RHEUMATOID ARTHRITIS

1996 • 160 citations

Sustained Induction of Prostaglandin Endoperoxide Synthase-2 by Seizures in Hippocampus

1996 • 160 citations

Sleep-wake regulation by prostaglandins D2 and E2.

1988 • 157 citations

Platelet-activating factor and retinoic acid synergistically activate the inducible prostaglandin synthase gene.

1994 • 152 citations

Clusterin (SGP‐2): A multifunctional glycoprotein with regional expression in astrocytes and neurons of the adult rat brain

1994 • 149 citations

Complement C1qB and C4 mRNAs responses to lesioning in rat brain

1992 • 139 citations

Induction of cyclooxygenase-2 mRNA and protein following transient focal ischemia in the rat brain

1995 • 123 citations

Cycloheximide prevents kainate-induced neuronal death and c-fos expression in adult rat brain

1993 • 107 citations

Development of excitotoxicity in cultured hippocampal neurons

1989 • 105 citations

Alternative splicing of human prostaglandin G/H synthase mRNA and evidence of differential regulation of the resulting transcripts by transforming growth factor beta 1, interleukin 1 beta, and tumor necrosis factor alpha.

1992 • 97 citations

Indomethacin ameliorates ischemic neuronal damage in the gerbil hippocampal CA1 sector.

1988 • 95 citations

Nonsteroidal antiinflammatory drug use in Alzheimer's disease

1994 • 76 citations

Platelet‐activating factor is a messenger in the electroconvulsive shock‐induced transcriptional activation of c‐fos and zif‐268 in hippocampus

1994 • 65 citations

SUPPRESSIVE EFFECT OF PROSTAGLANDIN (PG)D₂ON PULSATILE LUTEINIZING HORMONE RELEASE IN CONSCIOUS CASTRATED RATS

1982 • 64 citations

Distinct localization of prostaglandin D2, E2, and F2α binding sites in monkey brain

1989 • 45 citations

Expression of prostaglandin endoperoxide synthase in rat brain

1993 • 37 citations

Limbic Seizures Induced by Systemically Applied Kainic Acid: How Much Kainic Acid Reaches the Brain?

1986 • 36 citations

Effect of Temperature and Calcium on the Binding Properties of the AMPA Receptor in Frozen Rat Brain Sections

1992 • 23 citations