Immunobiology of muscle: advances in understanding an immunological microenvironment

THE B7 FAMILY REVISITED

2005 • 2,239 citations

Polymyositis and dermatomyositis

2003 • 1,331 citations

Co-inhibitory molecules of the B7–CD28 family in the control of T-cell immunity

2004 • 1,213 citations

Polymyositis and Dermatomyositis

1994 • 1,102 citations

Monoclonal antibody analysis of mononuclear cells in myopathies. I: Quantitation of subsets according to diagnosis and sites of accumulation and demonstration and counts of muscle fibers invaded by T cells

1984 • 621 citations

Dynamics of Myoblast Transplantation Reveal a Discrete Minority of Precursors with Stem Cell–like Properties as the Myogenic Source

1999 • 501 citations

Development of Approaches to Improve Cell Survival in Myoblast Transfer Therapy

1998 • 464 citations

Unravelling the pathogenesis of myasthenia gravis

2002 • 399 citations

Isolation and characterization of human muscle cells.

1981 • 398 citations

Proteasome and peptidase function in MHC-class-I-mediated antigen presentation

2003 • 387 citations

Major histocompatibility complex class I antigen expression, immunolocalization of interferon subtypes, and T cell-mediated cytotoxicity in myopathies

1989 • 343 citations

Expression of immunoreactive major histocompatibility complex products in human skeletal muscles

1988 • 324 citations

HLA-G1-expressing antigen-presenting cells induce immunosuppressive CD4⁺T cells

2004 • 314 citations

Conditional up-regulation of MHC class I in skeletal muscle leads to self-sustaining autoimmune myositis and myositis-specific autoantibodies

2000 • 302 citations

The immunobiology of muscle

1994 • 255 citations

Differential expression of perforin in muscle-infiltrating T cells in polymyositis and dermatomyositis.

1996 • 246 citations

Matrix metalloproteinases and skeletal muscle: A brief review

2004 • 216 citations

Nonclassical HLA-G molecules are classical peptide presenters

1996 • 201 citations

HLA-G: a shield against inflammatory aggression

2001 • 187 citations

A variety of cytokines and immunologically relevant surface molecules are expressed by normal human skeletal muscle cells under proinflammatory stimuli

1998 • 177 citations

Human myoblasts as antigen presenting cells

1991 • 163 citations

Myogenic stem cells for the therapy of primary myopathies: wishful thinking or therapeutic perspective?

2000 • 157 citations

Cytokines, chemokines, and cell adhesion molecules in inflammatory myopathies

2003 • 156 citations

Monoclonal antibody analysis of mononuclear cells in myopathies. IV: Cell‐mediated cytotoxicity and muscle fiber necrosis

1988 • 147 citations

Human myoblasts as antigen-presenting cells.

1992 • 145 citations

Skeletal Muscle Fibers Express Major Histocompatibility Complex Class II Antigens Independently of Inflammatory Infiltrates in Inflammatory Myopathies

2001 • 144 citations

Increased CD40 Expression on Muscle Cells of Polymyositis and Dermatomyositis: Role of CD40-CD40 Ligand Interaction in IL-6, IL-8, IL-15, and Monocyte Chemoattractant Protein-1 Production

2000 • 140 citations

Expression of matrix metalloproteinases in the muscle of patients with inflammatory myopathies

2000 • 136 citations

T cell receptor repertoire in polymyositis: clonal expansion of autoaggressive CD8+ T cells.

1995 • 134 citations

Cytotoxic mechanisms in inflammatory myopathies. Co-expression of Fas and protective Bcl-2 in muscle fibres and inflammatory cells

1997 • 132 citations

Anatomic localization of immature and mature dendritic cell subsets in dermatomyositis and polymyositis: Interaction with chemokines and Th1 cytokine–producing cells

2004 • 130 citations

Macrophages and dendritic cells in normal and regenerating murine skeletal muscle

1997 • 128 citations

HLA-G and HLA-E: fundamental and pathophysiological aspects

2000 • 119 citations

Muscle fibres and cultured muscle cells express the B7.1/2-related inducible co-stimulatory molecule, ICOSL: implications for the pathogenesis of inflammatory myopathies

2003 • 116 citations

Constitutive and cytokine-induced expression of human leukocyte antigens and cell adhesion molecules by human myotubes.

1993 • 110 citations

Expression of the Costimulatory Molecule BB-1, the Ligands CTLA-4 and CD28, and their mRNA in Inflammatory Myopathies

1999 • 110 citations

Clonal tracking of autoaggressive T cells in polymyositis by combining laser microdissection, single-cell PCR, and CDR3-spectratype analysis

2003 • 109 citations

The Inhibition of Apoptosis in Myositis and in Normal Muscle Cells

2000 • 108 citations

Human muscle cells express a B7‐related molecule, B7‐H1, with strong negative immune regulatory potential: a novel mechanism of counterbalancing the immune attack in idiopathic inflammatory myopathies

2003 • 108 citations

Coculture with autologous myotubes of cytotoxic T cells isolated from muscle in inflammatory myopathies

1991 • 101 citations

Muscle fibers in inflammatory myopathies and cultured myoblasts express the nonclassical major histocompatibility antigen HLA-G

2000 • 100 citations

Upregulated inducible co-stimulator (ICOS) and ICOS-ligand in inclusion body myositis muscle: significance for CD8+ T cell cytotoxicity

2004 • 100 citations

Human Muscle Cells Express a Functional Costimulatory Molecule Distinct from B7.1 (CD80) and B7.2 (CD86) In Vitro and in Inflammatory Lesions

1998 • 99 citations

Proteasomal Expression, Induction of Immunoproteasome Subunits, and Local MHC Class I Presentation in Myofibrillar Myopathy and Inclusion Body Myositis

2004 • 97 citations

Expression of specific matrix metalloproteinases in inflammatory myopathies

2001 • 97 citations

The non-classical MHC molecule HLA-G protects human muscle cells from immune-mediated lysis: implications for myoblast transplantation and gene therapy

2002 • 95 citations

Modulation of MHC class II antigen expression in human myoblasts after treatment with IFN‐γ

1991 • 81 citations

Expression of Calcium-Binding Proteins MRP8 and MRP14 in Inflammatory Muscle Diseases

2003 • 79 citations

Immunobiology and the Future of Myoblast Transfer Therapy

2000 • 79 citations

Immunological capabilities of skeletal muscle cells

2001 • 71 citations

Monocyte-derived HLA-G acts as a strong inhibitor of autologous CD4 T cell activation and is upregulated by interferon-β in vitro and in vivo: rationale for the therapy of multiple sclerosis

2004 • 70 citations

Cathepsins Are Upregulated by IFN-γ/STAT1 in Human Muscle Culture: A Possible Active Factor in Dermatomyositis

2001 • 57 citations

Immunotherapeutic gene transfer into muscle

2001 • 56 citations

Expression of human IAP-like protein in skeletal muscle: a possible explanation for the rare incidence of muscle fiber apoptosis in T-cell mediated inflammatory myopathies

2000 • 56 citations

CpG motifs of DNA vaccines induce the expression of chemokines and MHC class II molecules on myocytes

2001 • 47 citations

The BB1 Monoclonal Antibody Recognizes Both Cell Surface CD74 (MHC Class II-Associated Invariant Chain) as Well as B7-1 (CD80), Resolving the Question Regarding a Third CD28/CTLA-4 Counterreceptor

1998 • 45 citations

Antigen processing and presentation in human muscle: cathepsin S is critical for MHC class II expression and upregulated in inflammatory myopathies

2003 • 45 citations

Calpain and Cathepsins in the Skeletal Muscle of Inflammatory Myopathies

1997 • 44 citations

Update on immunopathogenesis in inflammatory myopathies

2001 • 44 citations

Lysis of myotubes by alloreactive cytotoxic T cells and natural killer cells. Relevance to myoblast transplantation.

1990 • 43 citations

Presentation by myoblasts of an epitope from endogenous acetylcholine receptor indicates a potential role in the spreading of the immune response

2001 • 43 citations

Monocyte/macrophage differentiation in dermatomyositis and polymyositis

2004 • 42 citations

An Autoreactive γδ TCR Derived from a Polymyositis Lesion

2002 • 38 citations

Human Fibroblasts Transduced with CD80 or CD86 Efficientlytrans-Costimulate CD4+ and CD8+ T Lymphocytes in HLA-Restricted Reactions: Implications for Immune Augmentation Cancer Therapy and Autoimmunity

1999 • 38 citations

Expression of HLA-DR and its enhancing molecules in muscle fibers in polymyositis

2000 • 36 citations

Induction of primary immune responses by allogeneic human myoblasts: dissection of the cell types required for proliferation, IFNγ secretion and cytotoxicity

1998 • 34 citations

Antigen processing and presentation by a murine myoblast cell line

1995 • 34 citations

Myoblasts fail to stimulate T cells but induce tolerance

1994 • 34 citations

Express and protect yourself: the potential role of HLA-G on muscle cells and in inflammatory myopathies

2003 • 33 citations

Expression of major histocompatibility complex antigens on human myoblasts.

1991 • 28 citations

The immunopathogenic role of complement in human muscle disease

1996 • 28 citations

The expression of co-stimulatory and accessory molecules on cultured human muscle cells is not dependent on stimulus by pro-inflammatory cytokines: relevance for the pathogenesis of inflammatory myopathy

1998 • 22 citations

TGF-β1 and IL-10 modulate IL-1β-induced membrane and soluble ICAM-1 in human myoblasts

2003 • 21 citations

Expression of Selectin Families and Their Ligand Sialyl Lewis X in the Muscles of Inflammatory Myopathies. An Immunohistochemical Study.

1999 • 9 citations