Polymorphic Analysis of the Human MHC‐Linked Heat Shock Protein 70 (HSP70‐2) and HSP70‐Hom Genes in Insulin‐Dependent Diabetes Mellitus (IDDM)

HLA‐DR typing by PCR amplification with sequence‐specific primers (PCR‐SSP) in 2 hours: An alternative to serological DR typing in clinical practice including donor‐recipient matching in cadaveric transplantation

1992 • 1,846 citations

HLA and Disease Associations

1985 • 893 citations

Association of tumor necrosis factor (TNF) and class II major histocompatibility complex alleles with the secretion of TNF‐a and TNF‐0 by human mononuclear cells: a possible link to insulin‐dependent diabetes mellitus

1993 • 562 citations

Cytotoxicity of Human p I 7 Interleukin-1 for Pancreatic Islets of Langerhans

1986 • 525 citations

Structure and expression of the three MHC-linked HSP70 genes

1990 • 397 citations

Nature of polymorphism in HLA-A, -B, and -C molecules.

1988 • 379 citations

Allelic sequence variation of the HLA-DQ loci: relationship to serology and to insulin-dependent diabetes susceptibility.

1988 • 378 citations

Human major histocompatibility complex contains genes for the major heat shock protein HSP70.

1989 • 336 citations

[1] High-efficiency cloning of full-length cDNA; Construction and screening of cDNA expression libraries for mammalian cells

1987 • 329 citations

Inhibitory Effects of Interleukin 1 on Insulin Secretion, Insulin Biosynthesis, and Oxidative Metabolism of Isolated Rat Pancreatic Islets*

1987 • 278 citations

Complex regulation of heat shock- and glucose-responsive genes in human cells.

1988 • 242 citations

A hypothetical model for the peptide binding domain of hsp70 based on the peptide binding domain of HLA.

1991 • 191 citations

DNA sequence polymorphism at the human tumor necrosis factor (TNF) locus. Numerous TNF/lymphotoxin alleles tagged by two closely linked microsatellites in the upstream region of the lymphotoxin (TNF-beta) gene.

1991 • 186 citations

Identification of multiple HTF-island associated genes in the human major histocompatibility complex class III region.

1989 • 183 citations

Cytokines Cause Functional and Structural Damage to Isolated Islets of Langerhans

1985 • 180 citations

Polymorphic analysis of the three MHC-linked HSP70 genes

1992 • 162 citations

The amino acid at position 57 of the HLA-DQB chain and susceptibility to develop insulin-dependent diabetes mellitus

1989 • 135 citations

Distribution of HLA class II alleles among Norwegian caucasians

1990 • 119 citations

Dose Effect of Cis- and Trans-Encoded HLA-DQαβ Heterodimers in IDDM Susceptibility

1992 • 105 citations

Dose effect of cis- and trans-encoded HLA-DQ alpha beta heterodimers in IDDM susceptibility

1992 • 103 citations

Stress Proteins, Autoimmunity, and Autoimmune Disease

1991 • 102 citations

Heat shock protein induction in rat pancreatic islets by recombinant human interleukin 1?

1991 • 85 citations

Liposomal Delivery of Purified Heat Shock Protein hsp70 Into Rat Pancreatic Islets as Protection Against Interleukin 1β–Induced Impaired β-Cell Function

1991 • 84 citations

Chromosomal location of human genes encoding major heat-shock protein HSP70

1987 • 77 citations

Localization of heat shock protein 70 genes inside the rat major histocompatibility complex close to class III genes

1989 • 61 citations

Conservation of the central MHC genome: PFGE mapping and RFLP analysis of complement, HSP70, and TNF genes in the goat

1990 • 57 citations

Complement C4 and heat shock protein 70 (HSP70) genotypes and type I diabetes mellitus

1990 • 54 citations

Particular HLA-DQ αβ Heterodimer Associated With IDDM Susceptibility in Both DR4-DQw4 Japanese and DR4-DQw8/DRw8-DQw4 Whites

1991 • 47 citations

A Role for Heat Shock Proteins in Antigen Processing and Presentation

1991 • 46 citations

Strong genetic association between HLA-DR3 and a polymorphic variation in the regulatory region of the HSP70-1 gene

1993 • 35 citations

No Independent Association Between HSP70 Gene Polymorphism and IDDM

1992 • 28 citations

Particular HLA-DQ alpha beta heterodimer associated with IDDM susceptibility in both DR4-DQw4 Japanese and DR4-DQw8/DRw8-DQw4 whites

1991 • 20 citations

Linkage of the mouse Hsp84 heat shock protein structural gene to the H-2 complex

1989 • 18 citations

No independent association between HSP70 gene polymorphism and IDDM

1992 • 18 citations

Liposomal delivery of purified heat shock protein hsp70 into rat pancreatic islets as protection against interleukin 1 beta-induced impaired beta-cell function

1991 • 17 citations

An MHC (HLA‐A, ‐B, C2, BF, HLA‐DR, GLO1) haplotype study of 497 Danish normal families with 1970 children including 97 twin pairs

1990 • 14 citations