Collagen Synthesis by Liver Stellate Cells Is Released from Its Normal Feedback Regulation by Acetaldehyde‐Induced Modification of the Carboxyl‐Terminal Propeptide of Procollagen

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Use of a mixture of proteinase-free collagenases for the specific assay of radioactive collagen in the presence of other proteins

1971 • 1,396 citations

Polypeptides of the tail fibres of bacteriophage T4

1971 • 956 citations

Purified Rat Liver Fat-Storing Cells in Culture Divide and Contain Collagen

1984 • 326 citations

Inhibiting effect of procollagen peptides on collagen biosynthesis in fibroblast cultures.

1979 • 255 citations

Acetaldehyde selectively stimulates collagen production in cultured rat liver fat-storing cells but not in hepatocytes

1990 • 243 citations

Acetaldehyde increases procollagen type I and fibronectin gene transcription in cultured rat fat-storing cells through a protein synthesis–dependent mechanism

1991 • 185 citations

In vitro differentiation of fat-storing cells parallels marked increase of collagen synthesis and secretion

1989 • 175 citations

Immunohistochemical demonstration of acetaldehyde-modified epitopes in human liver after alcohol consumption.

1991 • 155 citations

Detection of a protein-acetaldehyde adduct in the liver of rats fed alcohol chronically.

1988 • 152 citations

Acetaldehyde increases collagen gene transcription in cultured human fibroblasts.

1987 • 143 citations

Acetaldehyde and lactate stimulate collagen synthesis of cultured baboon liver myofibroblasts

1984 • 139 citations

Purification and characterization of a peptide from the carboxy-terminal region of chick tendon procollagen type I

1977 • 130 citations

The role of alcoholism and liver disease in the appearance of serum antibodies against acetaldehyde adducts

1988 • 120 citations

Evidence for pretranslational regulation of collagen synthesis by procollagen propeptides.

1986 • 116 citations

Blood acetaldehyde concentration gradient between hepatic and antecubital venous blood in ethanol-intoxicated alcoholics and controls*

1984 • 95 citations

Acetaldehyde Stimulates Collagen and Noncollagen Protein Production by Human Fibroblasts

1984 • 88 citations

Interchain disulfide bonds at the COOH-terminal end of procollagen synthesized by matrix-free cells from chick embryonic tendon and cartilage

1976 • 77 citations

Acetaldehyde increases procollagen type I and fibronectin gene transcription in cultured rat fat-storing cells through a protein synthesis-dependent mechanism, ,

1991 • 77 citations

Immunoglobulin a antibody to a 200-kilodalton cytosolic acetaldehyde adduct in alcoholic hepatitis

1992 • 60 citations

[4] Preparation and characterization of procollagens and procollagen-collagen intermediates

1982 • 56 citations

Characteristics of alcohol dehydrogenase in fat-storing (Ito) cells of rat liver

1988 • 55 citations

High levels of acetaldehyde in nonalcoholic liver injury after threonine or ethanol administration

1989 • 43 citations

Collagen-acetaldehyde adducts in alcoholic and nonalcoholic liver diseases

1994 • 39 citations

Cellular and subcellular localization of acetaldehyde-protein adducts in liver biopsies from alcoholic patients.

1996 • 35 citations

Effects of ethanol on prostanoid production by liver fat-storing cells.

1993 • 32 citations

Feedback regulation of collagen gene expression: a Trojan horse approach.

1991 • 31 citations

Zonal distribution of protein-acetaldehyde adducts in the liver of rats fed alcohol for long periods

1993 • 29 citations

Acetaldehyde-collagen adducts in CCL4-induced liver injury in rats

1990 • 27 citations

Effects of ethanol on prostanoid production by liver fat-storing cells

1993 • 27 citations

Covalent binding of acetaldehyde to type III collagen

1989 • 27 citations

Acetaldehyde-collagen adducts in N-nitrosodimethylamine-induced liver cirrhosis in rats

1993 • 23 citations

Effects of liver disease on red blood cell acetaldehyde in alcoholics and non-alcoholics.

1991 • 10 citations

Hemodynamic effects of a combination of propranolol and clonidine in patients with postnecrotic cirrhosis

1993 • 6 citations

THE <italic>IN VITRO</italic> BINDING OF ACETALDEHYDE TO COLLAGEN STUDIED BY NEUTRON DIFFRACTION<xref ref-type="fn" rid="fn1"><sup>*</sup></xref>

1994 • 5 citations