New findings in pharmacological effects induced by antihistamines: from PET studies to knock‐out mice

Quantification of Sleepiness: A New Approach

1973 • 2,454 citations

Histaminergic transmission in the mammalian brain

1991 • 948 citations

International Union of Pharmacology. XIII. Classification of histamine receptors.

1997 • 869 citations

Distribution of the histaminergic neuron system in the central nervous system of rats; a fluorescent immunohistochemical analysis with histidine decar☐ylase as a marker

1984 • 813 citations

Histamine-containing neurons in the rat hypothalamus.

1984 • 719 citations

Distribution, properties, and functional characteristics of three classes of histamine receptor.

1990 • 579 citations

Molecular pharmacological aspects of histamine receptors

1995 • 353 citations

The Pharmacology and Use of H₁-Receptor-Antagonist Drugs

1994 • 326 citations

Impaired locomotor activity and exploratory behavior in mice lacking histamine H ₁ receptors

1996 • 298 citations

PET evaluation of the dopamine system of the human brain.

1996 • 249 citations

Neuropharmacology of the histaminergic neuron system in the brain and its relationship with behavioral disorders

1994 • 245 citations

Broad host range plasmids carrying the Escherichia coli lactose and galactose operons

1992 • 178 citations

Behavioural characterization and amounts of brain monoamines and their metabolites in mice lacking histamine H1 receptors

1998 • 157 citations

Mechanisms of antihistamine-induced sedation in the human brain: H1 receptor activation reduces a background leakage potassium current

1994 • 138 citations

The role of positron emission tomography within the spectrum of medical imaging

1996 • 110 citations

Histamine H₁ receptor occupancy in human brains after single oral doses of histamine H₁ antagonists measured by positron emission tomography

1995 • 108 citations

Antidepressants and seizures: Clinical anecdotes overshadow neuroscience

1996 • 96 citations

Imaging the living human brain: Magnetic resonance imaging and positron emission tomography

1997 • 82 citations

THE EFFECT OF ANTIHISTAMINIC DRUGS ON CONVULSIVE SEIZURES

1949 • 79 citations

Sedative effects of antihistamines: safety, performance, learning, and quality of life

1997 • 76 citations

ANTIHISTAMINES AND SEDATION

1983 • 72 citations

AGE-DEPENDENT DECREASE IN HISTAMINE H1 RECEPTOR IN HUMAN BRAINS REVEALED BY PET

1992 • 65 citations

Histamine H1 receptors in human brain visualized in vivo by [11C]doxepin and positron emission tomography

1992 • 60 citations

Mapping of Histamine H₁ Receptors in the Human Brain Using [¹¹C]Pyrilamine and Positron Emission Tomography

1992 • 57 citations

Characterization of daytime sleepiness and psychomotor performance following H1 receptor antagonists.

1995 • 56 citations

Proconvulsant effect of ketotifen, a histamine H1 antagonist, confirmed by the use of d-chlorpheniramine with monitoring electroencephalography.

1993 • 55 citations

Sedation and Performance Issues in the Treatment of Allergic Conditions

1997 • 55 citations

Targeting disruption of histamine H1 receptors in mice: Behavioral and neurochemical characterization

1998 • 46 citations

ROLE OF THE CENTRAL HISTAMINERGIC NEURONAL SYSTEM IN THE CNS TOXICITY OF THE FIRST GENERATION H1-ANTAGONISTS

1997 • 40 citations

Positron emission tomographic study of central histamine H1-receptor occupancy in human subjects treated with epinastine, a second-generation antihistamine.

1995 • 38 citations

Sedation and performance issues in the treatment of allergic conditions

1997 • 13 citations

Antisense oligodeoxynucleotide directed to histamine H1 receptor decreases brain H1 receptor density with altered circadian rhythms

1998 • 1 citations