Glatiramer acetate improves regulatory T-cell function by expansion of naive CD4+CD25+FOXP3+CD31+ T-cells in patients with multiple sclerosis

New diagnostic criteria for multiple sclerosis: Guidelines for research protocols

1983 • 7,404 citations

Recommended diagnostic criteria for multiple sclerosis: Guidelines from the international panel on the diagnosis of multiple sclerosis

2001 • 6,888 citations

Loss of Functional Suppression by CD4+CD25+ Regulatory T Cells in Patients with Multiple Sclerosis

2004 • 1,835 citations

Reduced suppressive effect of CD4+CD25high regulatory T cells on the T cell immune response against myelin oligodendrocyte glycoprotein in patients with multiple sclerosis

2005 • 439 citations

Only the CD45RA+ subpopulation of CD4+CD25high T cells gives rise to homogeneous regulatory T-cell lines upon in vitro expansion

2006 • 407 citations

A peripheral circulating compartment of natural naive CD4+ Tregs

2005 • 299 citations

Persistence of naive CD45RA+ regulatory T cells in adult life

2005 • 267 citations

Induction of CD4⁺CD25⁺regulatory T cells by copolymer-I through activation of transcription factor Foxp3

2005 • 265 citations

Natural Naive CD4+CD25+CD127low Regulatory T Cell (Treg) Development and Function Are Disturbed in Multiple Sclerosis Patients: Recovery of Memory Treg Homeostasis during Disease Progression

2008 • 250 citations

Prevalence of Newly Generated Naive Regulatory T Cells (Treg) Is Critical for Treg Suppressive Function and Determines Treg Dysfunction in Multiple Sclerosis

2007 • 246 citations

Differential mechanisms of action of interferon-β and glatiramer acetate in MS

2002 • 238 citations

Naive regulatory T cells: a novel subpopulation defined by resistance toward CD95L-mediated cell death

2006 • 170 citations

Interferon Beta–Induced Restoration of Regulatory T-Cell Function in Multiple Sclerosis Is Prompted by an Increase in Newly Generated Naive Regulatory T Cells

2008 • 88 citations

What do we know about the mechanism of action of disease-modifying treatments in MS?

2004 • 79 citations

CD4+CD25+FoxP3+PD1— regulatory T cells in acute and stable relapsing‐remitting multiple sclerosis and their modulation by therapy

2008 • 71 citations

Effect of glatiramer acetate (Copaxone®) on the immunophenotypic and cytokine profile and BDNF production in multiple sclerosis: A longitudinal study

2006 • 53 citations